Publications by authors named "Prakash Manikwar"

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Spray drying process challenges and considerations for inhaled biologics.
Sadegh Poozesh, Patrick Connaughton, Scott Sides, David Lechuga-Ballesteros, Sajal M Patel, Prakash Manikwar

J Pharm Sci· February 2025

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Rapid Room-Temperature Aerosol Dehydration Versus Spray Drying: A Novel Paradigm in Biopharmaceutical Drying Technologies.
Sadegh Poozesh, Maksim Mezhericher, Zehao Pan, Uzair Chaudhary, Prakash Manikwar

J Pharm Sci· April 2024

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Sensitivity and Uncertainty Analysis of Micro-Flow Imaging for Sub-Visible Particle Measurements Using Artificial Neural Network.
Sadegh Poozesh, Flavio Cannavò, Prakash Manikwar

Pharm Res· March 2023

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Characterization of a Novel Bispecific Antibody With Improved Conformational and Chemical Stability.
Prakash Manikwar, Sri Hari Raju Mulagapati, Srinath Kasturirangan, Khashayar Moez, Godfrey Jonah Rainey

J Pharm Sci· January 2020

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Preformulation Characterization, Stabilization, and Formulation Design for the Acrylodan-Labeled Glucose-Binding Protein SM4-AC.
Neha Sahni, Rajoshi Chaudhuri, John M Hickey, Prakash Manikwar, Ajit D'Souza

J Pharm Sci· May 2017

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Both Reversible Self-Association and Structural Changes Underpin Molecular Viscoelasticity of mAb Solutions.
Prasad S Sarangapani, Justin Weaver, Arun Parupudi, Tabot M D Besong, Gary G Adams, Prakash Manikwar

J Pharm Sci· December 2016

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Mechanism of a decrease in potency for the recombinant influenza A virus hemagglutinin H3 antigen during storage.
John M Hickey, Kathleen M Holtz, Prakash Manikwar, Sangeeta B Joshi, Clifton E McPherson

J Pharm Sci· March 2014

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Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass spectrometry.
Prakash Manikwar, Ranajoy Majumdar, John M Hickey, Santosh V Thakkar, Hardeep S Samra

J Pharm Sci· July 2013

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Analytical lessons learned from selected therapeutic protein drug comparability studies.
Marcia Federici, Anthony Lubiniecki, Prakash Manikwar, David B Volkin

Biologicals· May 2013

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Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody.
Ranajoy Majumdar, Prakash Manikwar, John M Hickey, Hardeep S Samra, Hasige A Sathish

Biochemistry· May 2013

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Vaccinelike and prophylactic treatments of EAE with novel I-domain antigen conjugates (IDAC): targeting multiple antigenic peptides to APC.
Barlas Büyüktimkin, Prakash Manikwar, Paul K Kiptoo, Ahmed H Badawi, John M Stewart

Mol Pharm· January 2013

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Minimizing carry-over in an online pepsin digestion system used for the H/D exchange mass spectrometric analysis of an IgG1 monoclonal antibody.
Ranajoy Majumdar, Prakash Manikwar, John M Hickey, Jayant Arora, C Russell Middaugh

J Am Soc Mass Spectrom· December 2012

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Antigen-specific blocking of CD4-specific immunological synapse formation using BPI and current therapies for autoimmune diseases.
Prakash Manikwar, Paul Kiptoo, Ahmed H Badawi, Barlas Büyüktimkin, Teruna J Siahaan

Med Res Rev· July 2012

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I-domain-antigen conjugate (IDAC) for delivering antigenic peptides to APC: synthesis, characterization, and in vivo EAE suppression.
Prakash Manikwar, Barlas Büyüktimkin, Paul Kiptoo, Ahmed H Badawi, Nadezhda A Galeva

Bioconjug Chem· March 2012

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Utilization of I-domain of LFA-1 to Target Drug and Marker Molecules to Leukocytes.
Prakash Manikwar, Bimo A Tejo, Heather Shinogle, David S Moore, Tahl Zimmerman

Theranostics· July 2011

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Rapid identification of fluorochrome modification sites in proteins by LC ESI-Q-TOF mass spectrometry.
Prakash Manikwar, Tahl Zimmerman, Francisco J Blanco, Todd D Williams, Teruna J Siahaan

Bioconjug Chem· July 2011

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cIBR effectively targets nanoparticles to LFA-1 on acute lymphoblastic T cells.
Chuda Chittasupho, Prakash Manikwar, Jeffrey P Krise, Teruna J Siahaan, Cory Berkland

Mol Pharm· February 2010

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