Publications by authors named "Praphulla Shukla"

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The endothelium at the crossroads of multi-organ pathology: Insights from organ-on-chip models.
Swachhatoa Ghosh, Praphulla C Shukla, Soumen Das

Vascul Pharmacol· December 2025

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Vitamin D attenuates PCSK9-driven phenotypic switch of vascular smooth muscle cells and neointimal hyperplasia via SIRT6 activation.
Sushmitha Duddu, Yash T Katakia, Nivedha Suresh, Rituparna Chakrabarti, Syamantak Majumder, Praphulla Chandra Shukla

Biochim Biophys Acta Mol Basis Dis· December 2025

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Immunological and wound healing properties of keratin and its conformational variants extracted from ethically derived bio-resources.
Krishna Dixit, Linto John, Hema Bora, Anita Hansda, Baisakhee Saha, Praphulla Chandra Shukla

J Mater Chem B· October 2025

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Probing Shear-Induced Endothelial Activation in Vascular Conditions Using On-Chip Models.
Swachhatoa Ghosh, Shreya Mandal, Abhijit Das, Praphulla C Shukla, Soumen Das

ACS Biomater Sci Eng· May 2025

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New epigenome players in the regulation of PCSK9-H3K4me3 and H3K9ac alterations by statin in hypercholesterolemia.
Sushmitha Duddu, Yash T Katakia, Rituparna Chakrabarti, Pooja Sharma, Praphulla Chandra Shukla

J Lipid Res· January 2025

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Natural Killer T cells and the invariant subset promote atherosclerosis: A meta-analysis.
Rituparna Chakrabarti, Sushmitha Duddu, Ashutosh Tiwari, K Tejaswi Naidu, Pooja Sharma, Praphulla Chandra Shukla

Life Sci· May 2023

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Large-scale microRNA functional high-throughput screening identifies miR-515-3p and miR-519e-3p as inducers of human cardiomyocyte proliferation.
Harsha V Renikunta, Katina Lazarow, Yiqi Gong, Praphulla Chandra Shukla, Vanasa Nageswaran

iScience· May 2023

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Exploring the crosstalk between long non-coding RNAs and microRNAs to unravel potential prognostic and therapeutic biomarkers in β-thalassemia.
Motiur Rahaman, Mandrita Mukherjee, Shatarupa Bhattacharya, Budhaditya Mukherjee, Praphulla Chandra Shukla

Mol Biol Rep· July 2022

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Revisiting fetal hemoglobin inducers in beta-hemoglobinopathies: a review of natural products, conventional and combinatorial therapies.
Mandrita Mukherjee, Motiur Rahaman, Suman Kumar Ray, Praphulla Chandra Shukla, Tuphan Kanti Dolai

Mol Biol Rep· March 2022

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Proprotein convertase subtilisin/kexin type 9 (PCSK9): A potential multifaceted player in cancer.
Anindita Bhattacharya, Abhirup Chowdhury, Koel Chaudhury, Praphulla Chandra Shukla

Biochim Biophys Acta Rev Cancer· August 2021

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Inadvertent nucleotide sequence alterations during mutagenesis: highlighting the vulnerabilities in mouse transgenic technology.
Anuran Ghosh, Rituparna Chakrabarti, Praphulla Chandra Shukla

J Genet Eng Biotechnol· February 2021

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Hematopoietic Stem Cell Transcription Factors in Cardiovascular Pathology.
Sushmitha Duddu, Rituparna Chakrabarti, Anuran Ghosh, Praphulla Chandra Shukla

Front Genet· October 2020

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The forkhead transcription factor Foxo3 negatively regulates natural killer cell function and viral clearance in myocarditis.
Madlen Loebel, Luise Holzhauser, Jelka A Hartwig, Praphulla C Shukla, Konstantinos Savvatis

Eur Heart J· March 2018

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Glutathione adducts on sarcoplasmic/endoplasmic reticulum Ca2+ ATPase Cys-674 regulate endothelial cell calcium stores and angiogenic function as well as promote ischemic blood flow recovery.
Melissa D Thompson, Yu Mei, Robert M Weisbrod, Marcy Silver, Praphulla C Shukla

J Biol Chem· July 2014

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BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis.
Krishna K Singh, Praphulla C Shukla, Adrian Quan, Mohammed Al-Omran, Fina Lovren

J Thorac Cardiovasc Surg· October 2013

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Regulating cardiac energy metabolism and bioenergetics by targeting the DNA damage repair protein BRCA1.
Krishna K Singh, Praphulla C Shukla, Bobby Yanagawa, Adrian Quan, Fina Lovren

J Thorac Cardiovasc Surg· September 2013

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MicroRNA-145 targeted therapy reduces atherosclerosis.
Fina Lovren, Yi Pan, Adrian Quan, Krishna K Singh, Praphulla C Shukla

Circulation· September 2012

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miRNA-141 is a novel regulator of BMP-2-mediated calcification in aortic stenosis.
Bobby Yanagawa, Fina Lovren, Yi Pan, Vinay Garg, Adrian Quan, Praphulla C Shukla

J Thorac Cardiovasc Surg· July 2012

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BRCA2 protein deficiency exaggerates doxorubicin-induced cardiomyocyte apoptosis and cardiac failure.
Krishna K Singh, Praphulla C Shukla, Adrian Quan, Jean-François Desjardins, Fina Lovren

J Biol Chem· February 2012

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BRCA1 is an essential regulator of heart function and survival following myocardial infarction.
Praphulla C Shukla, Krishna K Singh, Adrian Quan, Mohammed Al-Omran, Hwee Teoh

Nat Commun· December 2011

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Herceptin, a recombinant humanized anti-ERBB2 monoclonal antibody, induces cardiomyocyte death.
Krishna K Singh, Praphulla C Shukla, Adrian Quan, Fina Lovren, Yi Pan

Biochem Biophys Res Commun· July 2011

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Effects on duration of post-operative ischemia and patterns of blood flow recovery in different conditions of mouse hind limb ischemia.
Husain A Al-Mubarak, Talal M Alamri, Saif A Aljabab, Mohammad Atteya, Adrian Quan, Praphulla C Shukla

Vasc Cell· June 2011

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Adiponectin primes human monocytes into alternative anti-inflammatory M2 macrophages.
Fina Lovren, Yi Pan, Adrian Quan, Paul E Szmitko, Krishna K Singh, Praphulla C Shukla

Am J Physiol Heart Circ Physiol· September 2010

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Adropin is a novel regulator of endothelial function.
Fina Lovren, Yi Pan, Adrian Quan, Krishna K Singh, Praphulla C Shukla

Circulation· September 2010

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Continuous glycoprotein-130-mediated signal transducer and activator of transcription-3 activation promotes inflammation, left ventricular rupture, and adverse outcome in subacute myocardial infarction.
Denise Hilfiker-Kleiner, Praphulla Shukla, Gunnar Klein, Arnd Schaefer, Britta Stapel

Circulation· July 2010

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