Publications by authors named "Prasanthi Geda"

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The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.
Christina K Baumgartner, Hakimeh Ebrahimi-Nik, Arvin Iracheta-Vellve, Keith M Hamel, Kira E Olander, Prasanthi Geda

Nature· October 2023

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Discovery of : an Efficient Inhibitor of the HDM2-p53 Protein-Protein Interaction.
Michael H Reutershan, Michelle R Machacek, Michael D Altman, Stephane Bogen, Mingmei Cai, Prasanthi Geda

J Med Chem· November 2021

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SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors.
Wensheng Yu, Yongqi Deng, Brett Hopkins, Xianhai Huang, David Sloman, Prasanthi Geda

Bioorg Med Chem Lett· September 2021

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Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 Inhibitors.
Brett Hopkins, Hongjun Zhang, Indu Bharathan, Derun Li, Qinglin Pu, Prasanthi Geda

ACS Med Chem Lett· September 2021

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Carbamate and -Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors.
Derun Li, Yongqi Deng, Abdelghani Achab, Indu Bharathan, Brett Andrew Hopkins, Prasanthi Geda

ACS Med Chem Lett· March 2021

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Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors.
Qinglin Pu, Hongjun Zhang, Liangqin Guo, Mangeng Cheng, Amy C Doty, Prasanthi Geda

ACS Med Chem Lett· August 2020

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Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase-1 (IDO1).
Catherine White, Meredeth A McGowan, Hua Zhou, Nunzio Sciammetta, Xavier Fradera, Prasanthi Geda

ACS Med Chem Lett· April 2020

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Characterizing Pharmacokinetic-Pharmacodynamic Relationships and Efficacy of PI3K Inhibitors in Respiratory Models of TH2 and TH1 Inflammation.
Robbie L McLeod, Malgorzata A Gil, Dapeng Chen, Antonio Cabal, Jason Katz, Prasanthi Geda

J Pharmacol Exp Ther· May 2019

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Development of Anti-CD74 Antibody-Drug Conjugates to Target Glucocorticoids to Immune Cells.
Philip E Brandish, Anthony Palmieri, Svetlana Antonenko, Maribel Beaumont, Lia Benso, Prasanthi Geda

Bioconjug Chem· July 2018

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Discovery of Pyrophosphate Diesters as Tunable, Soluble, and Bioorthogonal Linkers for Site-Specific Antibody-Drug Conjugates.
Jeffrey C Kern, Mark Cancilla, Deborah Dooney, Kristen Kwasnjuk, Rena Zhang, Prasanthi Geda

J Am Chem Soc· February 2016

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Conditional nuclear import and export of yeast proteins using a chemical inducer of dimerization.
Srikanth Patury, Prasanthi Geda, Craig J Dobry, Anuj Kumar, Jason E Gestwicki

Cell Biochem Biophys· July 2009

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A small molecule-directed approach to control protein localization and function.
Prasanthi Geda, Srikanth Patury, Jun Ma, Nike Bharucha, Craig J Dobry

Yeast· August 2008

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