Publications by authors named "Pui E Wong"

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An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics.
Fraser J Scott, Abedawn I Khalaf, Federica Giordani, Pui Ee Wong, Sandra Duffy

Eur J Med Chem· June 2016

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Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1.
Abedawn I Khalaf, Judith K Huggan, Colin J Suckling, Colin L Gibson, Kirsten Stewart, Pui Ee Wong

J Med Chem· August 2014

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Counterflow dielectrophoresis for trypanosome enrichment and detection in blood.
Anoop Menachery, Clemens Kremer, Pui E Wong, Allan Carlsson, Steven L Neale

Sci Rep· March 2013

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Synthesis and biological evaluation of CTP synthetase inhibitors as potential agents for the treatment of African trypanosomiasis.
Lucia Tamborini, Andrea Pinto, Terry K Smith, Louise L Major, Maria C Iannuzzi, Pui E Wong

ChemMedChem· September 2012

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Trypanocidal furamidine analogues: influence of pyridine nitrogens on trypanocidal activity, transport kinetics, and resistance patterns.
Christopher P Ward, Pui Ee Wong, Richard J Burchmore, Harry P de Koning, Michael P Barrett

Antimicrob Agents Chemother· May 2011

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Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity.
John Spencer, Rajendra P Rathnam, Alan L Harvey, Carol J Clements, Rachel L Clark, Pui Ee Wong

Bioorg Med Chem· March 2011

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Synthesis and in vitro/in vivo evaluation of the antitrypanosomal activity of 3-bromoacivicin, a potent CTP synthetase inhibitor.
Paola Conti, Andrea Pinto, Pui E Wong, Louise L Major, Lucia Tamborini

ChemMedChem· February 2011

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Polyamine aza-cyclic compounds demonstrate anti-proliferative activity in vitro but fail to control tumour growth in vivo.
Pui Ee Wong, Laurence Tetley, Christine Dufès, Kar Wai Chooi, Katherine Bolton

J Pharm Sci· November 2010

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A molecular mechanism for eflornithine resistance in African trypanosomes.
Isabel M Vincent, Darren Creek, David G Watson, Mohammed A Kamleh, Debra J Woods, Pui Ee Wong

PLoS Pathog· November 2010

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A glucose transporter can mediate ribose uptake: definition of residues that confer substrate specificity in a sugar transporter.
Christina M Naula, Flora J Logan, Pui Ee Wong, Michael P Barrett, Richard J Burchmore

J Biol Chem· September 2010

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Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif.
Nina Klee, Pui Ee Wong, Beatriz Baragaña, Farah El Mazouni, Margaret A Phillips

Bioorg Med Chem Lett· August 2010

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Aryl phosphoramidates of 5-phospho erythronohydroxamic acid, a new class of potent trypanocidal compounds.
Gian Filippo Ruda, Pui Ee Wong, Vincent P Alibu, Suzanne Norval, Kevin D Read

J Med Chem· August 2010

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Multiple genetic mechanisms lead to loss of functional TbAT1 expression in drug-resistant trypanosomes.
Mhairi L Stewart, Richard J S Burchmore, Caroline Clucas, Christiane Hertz-Fowler, Karen Brooks, Pui Ee Wong

Eukaryot Cell· February 2010

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Unsaturated Mannich bases active against multidrug-resistant Trypanosoma brucei brucei strains.
I Nicole Wenzel, Pui E Wong, Louis Maes, Thomas J J Müller, R Luise Krauth-Siegel

ChemMedChem· March 2009

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Targeted delivery of compounds to Trypanosoma brucei using the melamine motif.
Constance Chollet, Alessandro Baliani, Pui Ee Wong, Michael P Barrett, Ian H Gilbert

Bioorg Med Chem· March 2009

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