Publications by authors named "Pyry Koivula"

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Preclinical characterization and IND-enabling safety studies for PNT001, an antibody that recognizes cis-pT231 tau.
Kelly Foster, Matteo Manca, Kim McClure, Pyry Koivula, John Q Trojanowski

Alzheimers Dement· October 2023

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Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice.
Argyro Thalia Delizannis, Annelies Nonneman, Wangchen Tsering, An De Bondt, Ilse Van den Wyngaert, Pyry Koivula

Acta Neuropathol Commun· September 2021

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Neuronal Activation Stimulates Cytomegalovirus Promoter-Driven Transgene Expression.
Susanne Bäck, Amanda Dossat, Ilmari Parkkinen, Pyry Koivula, Mikko Airavaara

Mol Ther Methods Clin Dev· September 2019

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Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats.
Susanne Bäck, Julie Necarsulmer, Leslie R Whitaker, Lamarque M Coke, Pyry Koivula

Neuron· April 2019

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A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model.
Bin Zhang, Yuemang Yao, Anne-Sophie Cornec, Killian Oukoloff, Michael J James, Pyry Koivula

Mol Neurodegener· November 2018

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Neurons Internalize Functionalized Micron-Sized Silicon Dioxide Microspheres.
Veronica J Wallace, Raffaello Cimbro, F Javier Rubio, Lowella V Fortuno, Julie C Necarsulmer, Pyry P Koivula

Cell Mol Neurobiol· November 2017

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Lateral Hypothalamic GABAergic Neurons Encode Reward Predictions that Are Relayed to the Ventral Tegmental Area to Regulate Learning.
Melissa J Sharpe, Nathan J Marchant, Leslie R Whitaker, Christopher T Richie, Yajun J Zhang, Pyry P Koivula

Curr Biol· July 2017

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Near-infrared fluorescent protein iRFP713 as a reporter protein for optogenetic vectors, a transgenic Cre-reporter rat, and other neuronal studies.
Christopher T Richie, Leslie R Whitaker, Keith W Whitaker, Julie Necarsulmer, Heather A Baldwin, Pyry Koivula

J Neurosci Methods· June 2017

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Step Sequence Is a Critical Gait Parameter of Unilateral 6-OHDA Parkinson's Rat Models.
Heather A Baldwin, Pyry P Koivula, Julie C Necarsulmer, Keith W Whitaker, Brandon K Harvey

Cell Transplant· April 2017

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