Publications by authors named "Pyry Toivanen"

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Low dose Adenoviral Vammin gene transfer induces myocardial angiogenesis and increases left ventricular ejection fraction in ischemic porcine heart.
Niko Järveläinen, Paavo J Halonen, Jussi Nurro, Antti Kuivanen, Juho Pajula, Pyry Toivanen

Sci Rep· December 2024

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Antiangiogenic AAV2 gene therapy with a truncated form of soluble VEGFR-2 reduces the growth of choroidal neovascularization in mice after intravitreal injection.
Jooseppi Puranen, Sanna Koponen, Tiina Nieminen, Iiris Kanerva, Emmi Kokki, Pyry Toivanen

Exp Eye Res· November 2022

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Novel Designed Proteolytically Resistant VEGF-B186R127S Promotes Angiogenesis in Mouse Heart by Recruiting Endothelial Progenitor Cells.
Rahul Mallick, Erika Gurzeler, Pyry I Toivanen, Tiina Nieminen, Seppo Ylä-Herttuala

Front Bioeng Biotechnol· August 2022

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Adenoviral VEGF-B186R127S gene transfer induces angiogenesis and improves perfusion in ischemic heart.
Henna Korpela, Olli-Pekka Hätinen, Tiina Nieminen, Rahul Mallick, Pyry Toivanen

iScience· December 2021

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Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function.
Suvi Jauhiainen, Johanna P Laakkonen, Kirsi Ketola, Pyry I Toivanen, Tiina Nieminen

Front Physiol· March 2019

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Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up.
Juha Hartikainen, Iiro Hassinen, Antti Hedman, Antti Kivelä, Antti Saraste, Pyry Toivanen

Eur Heart J· September 2017

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Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling.
Pyry I Toivanen, Tiina Nieminen, Johanna P Laakkonen, Tommi Heikura, Minna U Kaikkonen

Sci Rep· July 2017

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Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8.
Johanna P Laakkonen, Jari P Lappalainen, Thomas L Theelen, Pyry I Toivanen, Tiina Nieminen

Angiogenesis· February 2017

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Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle via reduced eNOS activity.
Tiina Nieminen, Pyry I Toivanen, Johanna P Laakkonen, Tommi Heikura, Minna U Kaikkonen

Cardiovasc Res· July 2015

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The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features.
Tiina Nieminen, Pyry I Toivanen, Nina Rintanen, Tommi Heikura, Suvi Jauhiainen

Biochim Biophys Acta· January 2014

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Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer.
Laura Tuppurainen, Hanna Sallinen, Emmi Kokki, Jonna Koponen, Maarit Anttila, Pyry Toivanen

Hum Gene Ther Clin Dev· March 2013

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Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects.
Suvi Jauhiainen, Sanna-Kaisa Häkkinen, Pyry I Toivanen, Suvi E Heinonen, Henna-Kaisa Jyrkkänen

Arterioscler Thromb Vasc Biol· July 2011

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A laboratory-scale device for the straightforward production of uniform, small sized cell microcapsules with long-term cell viability.
Leena-Stiina Kontturi, Marjo Yliperttula, Pyry Toivanen, Antti Määttä, Ann-Marie Määttä

J Control Release· June 2011

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Structural determinants of vascular endothelial growth factor-D receptor binding and specificity.
Veli-Matti Leppänen, Michael Jeltsch, Andrey Anisimov, Denis Tvorogov, Kukka Aho, Pyry Toivanen

Blood· February 2011

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Novel vascular endothelial growth factor D variants with increased biological activity.
Pyry I Toivanen, Tiina Nieminen, Lenita Viitanen, Annamari Alitalo, Miia Roschier

J Biol Chem· June 2009

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A 96-well format for a high-throughput baculovirus generation, fast titering and recombinant protein production in insect and mammalian cells.
Hanna-Riikka Kärkkäinen, Hanna P Lesch, Antti I Määttä, Pyry I Toivanen, Anssi J Mähönen

BMC Res Notes· April 2009

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Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice.
Hanna Sallinen, Maarit Anttila, Johanna Narvainen, Jonna Koponen, Kirsi Hamalainen, Pyry Toivanen

Mol Ther· February 2009

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A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo.
Olli H Laitinen, Kari J Airenne, Vesa P Hytönen, Erik Peltomaa, Anssi J Mähönen, Pyry I Toivanen

Nucleic Acids Res· February 2005

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