Publications by authors named "Qi-Long Lu"

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Ribitol treatment rescues dystroglycanopathy mice with common L276I mutation.
Bo Wu, Pei Juan Lu, Morgan Drains, Sapana Shah, Anthony Blaeser, Qi Long Lu

PLoS One· August 2025

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In Vivo Evaluation of Dystrophin Exon Skipping in mdx Mice.
Bo Wu, Qi Long Lu

Methods Mol Biol· July 2025

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Improved efficacy of FKRP AAV gene therapy by combination with ribitol treatment for LGMD2I.
Marcela P Cataldi, Charles H Vannoy, Anthony Blaeser, Jason D Tucker, Victoria Leroy, Qi Long Lu

Mol Ther· December 2023

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Ribitol dose-dependently enhances matriglycan expression and improves muscle function with prolonged life span in limb girdle muscular dystrophy 2I mouse model.
Bo Wu, Morgan Drains, Sapana N Shah, Pei Juan Lu, Victoria Leroy, Qi Long Lu

PLoS One· December 2022

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Ribitol alters multiple metabolic pathways of central carbon metabolism with enhanced glycolysis: A metabolomics and transcriptomics profiling of breast cancer.
Jason Driver Tucker, Ravi Doddapaneni, Pei Juan Lu, Qi Long Lu

PLoS One· December 2022

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Revertant Phenomenon in DMD and LGMD2I and Its Therapeutic Implications: A Review of Study Under Mentorship of Terrence Partridge.
Qi Long Lu

J Neuromuscul Dis· December 2021

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Effects of Chronic, Maximal Phosphorodiamidate Morpholino Oligomer (PMO) Dosing on Muscle Function and Dystrophin Restoration in a Mouse Model of Duchenne Muscular Dystrophy.
Margaret E Benny Klimek, Maria Candida Vila, Katie Edwards, Jessica Boehler, James Novak, Qi Long Lu

J Neuromuscul Dis· December 2021

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A universal gene correction approach for FKRP-associated dystroglycanopathies to enable autologous cell therapy.
Neha R Dhoke, Hyunkee Kim, Sridhar Selvaraj, Karim Azzag, Haowen Zhou, Qi Long Lu

Cell Rep· July 2021

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ISPD Overexpression Enhances Ribitol-Induced Glycosylation of α-Dystroglycan in Dystrophic FKRP Mutant Mice.
Marcela P Cataldi, Anthony Blaeser, Peijuan Lu, Victoria Leroy, Qi Long Lu

Mol Ther Methods Clin Dev· June 2020

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Efficient engraftment of pluripotent stem cell-derived myogenic progenitors in a novel immunodeficient mouse model of limb girdle muscular dystrophy 2I.
Karim Azzag, Carolina Ortiz-Cordero, Nelio A J Oliveira, Alessandro Magli, Sridhar Selvaraj, Qi Long Lu

Skelet Muscle· April 2020

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Metabolomics Analysis of Skeletal Muscles from FKRP-Deficient Mice Indicates Improvement After Gene Replacement Therapy.
Charles Harvey Vannoy, Victoria Leroy, Katarzyna Broniowska, Qi Long Lu

Sci Rep· July 2019

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In Vivo Evaluation of Dystrophin Exon Skipping in mdx Mice.
Bo Wu, Mingxing Wang, Sapana Shah, Qi Long Lu

Methods Mol Biol· April 2019

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Dose-Dependent Effects of FKRP Gene-Replacement Therapy on Functional Rescue and Longevity in Dystrophic Mice.
Charles Harvey Vannoy, Victoria Leroy, Qi Long Lu

Mol Ther Methods Clin Dev· December 2018

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Ribitol restores functionally glycosylated α-dystroglycan and improves muscle function in dystrophic FKRP-mutant mice.
Marcela P Cataldi, Peijuan Lu, Anthony Blaeser, Qi Long Lu

Nat Commun· August 2018

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Skeletal, cardiac, and respiratory muscle function and histopathology in the P448Lneo- mouse model of FKRP-deficient muscular dystrophy.
Qing Yu, Melissa Morales, Ning Li, Alexander G Fritz, Ren Ruobing, Qi-Long Lu

Skelet Muscle· April 2018

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Distinct expression of functionally glycosylated alpha-dystroglycan in muscle and non-muscle tissues of FKRP mutant mice.
Anthony Blaeser, Hiroyuki Awano, Pei Lu, Qi-Long Lu

PLoS One· February 2018

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Progressive Dystrophic Pathology in Diaphragm and Impairment of Cardiac Function in FKRP P448L Mutant Mice.
Anthony Blaeser, Hiroyuki Awano, Bo Wu, Qi-Long Lu

PLoS One· June 2017

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Efficacy of Gene Therapy Is Dependent on Disease Progression in Dystrophic Mice with Mutations in the FKRP Gene.
Charles Harvey Vannoy, Will Xiao, Peijuan Lu, Xiao Xiao, Qi Long Lu

Mol Ther Methods Clin Dev· June 2017

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Glucocorticoid Steroid and Alendronate Treatment Alleviates Dystrophic Phenotype with Enhanced Functional Glycosylation of α-Dystroglycan in Mouse Model of Limb-Girdle Muscular Dystrophy with FKRPP448L Mutation.
Bo Wu, Sapana N Shah, Peijuan Lu, Stephanie M Richardson, Lauren E Bollinger, Taylor M Luckie, Qi Long Lu

Am J Pathol· June 2016

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Elusive sources of variability of dystrophin rescue by exon skipping.
Maria Candida Vila, Margaret Benny Klimek, James S Novak, Sree Rayavarapu, Kitipong Uaesoontrachoon, Qi Long Lu

Skelet Muscle· December 2015

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Adeno-associated virus-mediated overexpression of LARGE rescues α-dystroglycan function in dystrophic mice with mutations in the fukutin-related protein.
Charles H Vannoy, Lei Xu, Elizabeth Keramaris, Pei Lu, Xiao Xiao, Qi Long Lu

Hum Gene Ther Methods· June 2014

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Evaluation of Tris[2-(acryloyloxy)ethyl]isocyanurate cross-linked polyethylenimine as antisense morpholino oligomer delivery vehicle in cell culture and dystrophic mdx mice.
Mingxing Wang, Bo Wu, Jay D Tucker, Peijuan Lu, Caryn Cloer, Qi Long Lu

Hum Gene Ther· May 2014

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What Can We Learn From Clinical Trials of Exon Skipping for DMD?
Qi-Long Lu, Sebahattin Cirak, Terence Partridge

Mol Ther Nucleic Acids· March 2014

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Adeno-associated virus 9 mediated FKRP gene therapy restores functional glycosylation of α-dystroglycan and improves muscle functions.
Lei Xu, Pei Juan Lu, Chi-Hsien Wang, Elizabeth Keramaris, Chunping Qiao, Qi Long Lu

Mol Ther· October 2013

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Mouse models of fukutin-related protein mutations show a wide range of disease phenotypes.
Anthony Blaeser, Elizabeth Keramaris, Yiumo M Chan, Susan Sparks, Dale Cowley, Qi Long Lu

Hum Genet· August 2013

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