Publications by authors named "Qiaobing Xu"

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Spatial Conformation of Ionizable Lipids Regulates Endosomal Membrane Disruption.
Yu Zhao, Zhiyuan Qu, Markéta Paloncýová, Zeyu Wang, Benson Weng, Qiaobing Xu

J Am Chem Soc· October 2025

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base editing of Angptl3 via lipid nanoparticles to treat cardiovascular disease.
Jennifer Khirallah, Hanan Bloomer, Douglas Wich, Changfeng Huang, J Noah Workman, Qiaobing Xu

Mol Ther Nucleic Acids· June 2025

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Revolutionizing tissue regeneration: the art of mimicking diverse collagen-based extracellular matrix hierarchies with decellularized tendon via bioskiving.
Na Bai, Yamin Li, Qiaobing Xu, Tao Yang

Int J Biol Macromol· May 2025

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Orchestrated desaturation reprogramming from stearoyl-CoA desaturase to fatty acid desaturase 2 in cancer epithelial-mesenchymal transition and metastasis.
Zhicong Chen, Yanqing Gong, Fukai Chen, Hyeon Jeong Lee, Jinqin Qian, Qiaobing Xu

Cancer Commun (Lond)· March 2025

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Antitumour vaccination via the targeted proteolysis of antigens isolated from tumour lysates.
Yu Zhao, Donghui Song, Zeyu Wang, Qingqing Huang, Fan Huang, Qiaobing Xu

Nat Biomed Eng· February 2025

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Improving adenine base editing precision by enlarging the recognition domain of CRISPR-Cas9.
Shuliang Gao, Benson Weng, Douglas Wich, Liam Power, Mengting Chen, Chutian Xu, Qiaobing Xu

Nat Commun· February 2025

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ZUGC-RNA degradation generates immunosuppressor to evade immune responses in eukaryotes.
Shuliang Gao, Mengting Chen, Douglas Wich, Hanan Bloomer, Zhiyuan Qu, Qiaobing Xu

bioRxiv· January 2025

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Tuning Lipid Nanoparticles for RNA Delivery to Extrahepatic Organs.
Donghui Song, Yu Zhao, Zeyu Wang, Qiaobing Xu

Adv Mater· November 2024

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Rational design of lipid nanoparticles: overcoming physiological barriers for selective intracellular mRNA delivery.
Yu Zhao, Zeyu Morgan Wang, Donghui Song, Mengting Chen, Qiaobing Xu

Curr Opin Chem Biol· August 2024

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New ionizable lipids reduce the lipid-to-mRNA ratio for base editing.
Shuliang Gao, Qiaobing Xu

Natl Sci Rev· August 2024

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A prime editor mouse to model a broad spectrum of somatic mutations in vivo.
Zackery A Ely, Nicolas Mathey-Andrews, Santiago Naranjo, Samuel I Gould, Kim L Mercer, Qiaobing Xu

Nat Biotechnol· March 2024

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Investigating the Cytosolic Delivery of Proteins by Lipid Nanoparticles Using the Chloroalkane Penetration Assay.
Jing Wang, Shiying Zhang, Yamin Li, Qiaobing Xu, Joshua A Kritzer

Biochemistry· February 2024

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Harnessing non-Watson-Crick's base pairing to enhance CRISPR effectors cleavage activities and enable gene editing in mammalian cells.
Shuliang Gao, Huiwen Guan, Hanan Bloomer, Douglas Wich, Donghui Song, Chutian Xu, Qiaobing Xu

Proc Natl Acad Sci U S A· January 2024

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Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants.
Zhongfeng Ye, Srinivasa Reddy Bonam, Lindsay G A McKay, Jessica A Plante, Jordyn Walker, Chutian Xu, Qiaobing Xu

Proc Natl Acad Sci U S A· December 2023

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Nanomechanical action opens endo-lysosomal compartments.
Yu Zhao, Zhongfeng Ye, Donghui Song, Douglas Wich, Shuliang Gao, Qiaobing Xu

Nat Commun· October 2023

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The mRNA Vaccine Revolution: COVID-19 Has Launched the Future of Vaccinology.
Zhongfeng Ye, Joseph Harmon, Wei Ni, Yamin Li, Douglas Wich, Qiaobing Xu

ACS Nano· August 2023

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A high-throughput approach of screening nanoparticles for targeted delivery of mRNA.
Jennifer Khirallah, Qiaobing Xu

Cell Rep Methods· August 2023

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Correction to "Combinatorial Library of Lipidoids for In Vitro DNA Delivery".
Shuo Sun, Ming Wang, Sarah A Knupp, Yadira Soto-Feliciano, Xiao Hu, Qiaobing Xu

Bioconjug Chem· July 2023

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Gemini Amphiphiles: Robust Cytosolic Delivery of Therapeutic Biomacromolecules through Non-Endocytic Translocation Pathways.
Yu Zhao, Douglas Wich, Qiaobing Xu

ACS Cent Sci· July 2023

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Clinical progress in genome-editing technology and in vivo delivery techniques.
Jennifer Khirallah, Maximilan Eimbinder, Yamin Li, Qiaobing Xu

Trends Genet· March 2023

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A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta.
Brandon Carter, Pinghan Huang, Ge Liu, Yuejin Liang, Paulo J C Lin, Qiaobing Xu

Front Immunol· March 2023

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Lipidoid Artificial Compartments for Bidirectional Regulation of Enzyme Activity through Nanomechanical Action.
Yu Zhao, Shuliang Gao, Donghui Song, Zhongfeng Ye, Ruijie Xu, Qiaobing Xu

J Am Chem Soc· January 2023

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Engineering a Nano/Biointerface for Cell and Organ-Selective Drug Delivery.
Donghui Song, Qiaobing Xu

Langmuir· August 2022

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Lipid nanoparticle-mediated lymph node-targeting delivery of mRNA cancer vaccine elicits robust CD8 T cell response.
Jinjin Chen, Zhongfeng Ye, Changfeng Huang, Min Qiu, Donghui Song, Qiaobing Xu

Proc Natl Acad Sci U S A· August 2022

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Tailoring combinatorial lipid nanoparticles for intracellular delivery of nucleic acids, proteins, and drugs.
Yamin Li, Zhongfeng Ye, Hanyi Yang, Qiaobing Xu

Acta Pharm Sin B· June 2022

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