Publications by authors named "Qingduan Wang"

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FNC inhibits non-small cell lung cancer by activating the mitochondrial apoptosis pathway.
Xiang Jing, Shuai Niu, Yi Liang, Huiping Chen, Ning Wang, Qingduan Wang

Genes Genomics· January 2022

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In vitro and in vivo antiviral activity of a fluoronucleoside analog, NCC, against Coxsackie virus B3.
Yafeng Wang, Xiaokai Zhuan, Youmei Peng, Qing Li, Chenzheng Huang, Qingduan Wang

Acta Virol· April 2021

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The Antitumour Effect of Extract on Thyroid Cancer Cells In Vitro and In Vivo.
Fangqin Yu, Lele Zhang, Runsheng Ma, Chenguang Liu, Qingduan Wang

Evid Based Complement Alternat Med· January 2021

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Mechanistic Insight into Antiretroviral Potency of 2'-Deoxy-2'-β-fluoro-4'-azidocytidine (FNC) with a Long-Lasting Effect on HIV-1 Prevention.
Li Sun, Youmei Peng, Wenquan Yu, Yan Zhang, Lan Liang, Qingduan Wang, Jian-Hua Wang

J Med Chem· August 2020

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Novel fluoronucleoside analog NCC inhibits lamivudine-resistant hepatitis B virus in a hepatocyte model.
Jingmin Zhang, Yafeng Wang, Youmei Peng, Chongzhen Qin, Yixian Liu, Qingduan Wang

Braz J Infect Dis· March 2020

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Gingival crevicular fluid levels of SLIT3 are increased in periodontal disease.
Wei Zhong, Youmei Peng, Erli Yue, Bin Huang, Wei Zhang, Qingduan Wang

Oral Dis· January 2020

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Design, synthesis, and biological evaluation of novel 2'-deoxy-2'-fluoro-2'-C-methyl 8-azanebularine derivatives as potent anti-HBV agents.
Wu Yang, Youmei Peng, Jingwen Wang, Chuanjun Song, Wenquan Yu, Qingduan Wang

Bioorg Med Chem Lett· June 2019

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Effects of the antiretroviral drug 2'-deoxy-2'-β-fluoro-4'-azidocytidine (FNC) on P-gp, MRP2 and BCRP expressions and functions.
Yixian Liu, Yafeng Wang, Youmei Peng, Bingjie Liu, Fang Ma, Qingduan Wang

Pharmazie· September 2018

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Synthesis and biological evaluation of a novel β-D-2'-deoxy-2'-α-fluoro-2'-β-C-(fluoromethyl)uridine phosphoramidate prodrug for the treatment of hepatitis C virus infection.
Ertong Li, Yafeng Wang, Wenquan Yu, Zhigang Lv, Youmei Peng, Qingduan Wang

Eur J Med Chem· January 2018

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Cepharanthine hydrochloride reverses P‑glycoprotein-mediated multidrug resistance in human ovarian carcinoma A2780/Taxol cells by inhibiting the PI3K/Akt signaling pathway.
Chen-Zheng Huang, Ya-Feng Wang, Yan Zhang, You-Mei Peng, Yi-Xian Liu, Qing-Duan Wang

Oncol Rep· October 2017

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FNC efficiently inhibits mantle cell lymphoma growth.
Yan Zhang, Rong Zhang, Xixi Ding, Bangan Peng, Ning Wang, Qingduan Wang

PLoS One· August 2017

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Intestinal absorption mechanisms of 2'-deoxy-2'-β-fluoro-4'-azidocytidine, a cytidine analog for AIDS treatment, and its interaction with P-glycoprotein, multidrug resistance-associated protein 2 and breast cancer resistance protein.
Yixian Liu, Bingjie Liu, Yan Zhang, Youmei Peng, Chenzheng Huang, Ning Wang, Qingduan Wang

Eur J Pharm Sci· July 2017

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Discovery of an Orally Active and Liver-Targeted Prodrug of 5-Fluoro-2'-Deoxyuridine for the Treatment of Hepatocellular Carcinoma.
Youmei Peng, Wenquan Yu, Ertong Li, Jinfeng Kang, Yafeng Wang, Qingduan Wang

J Med Chem· April 2016

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Anti-hepatitis B virus activity of α-DDB-FNCG, a novel nucleoside-biphenyldicarboxylate compound in vitro and in vivo.
Qinghua Yang, Xuejie Zhao, Wenquan Yu, Wu He, Xianzhen Fang, Qingduan Wang

J Pharmacol Sci· October 2015

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Design, synthesis, and biological evaluation of new N(4)-Substituted 2'-deoxy-2'-fluoro-4'-azido cytidine derivatives as potent anti-HBV agents.
Zhigang Lv, Wu He, Xianhai Tian, Jinfeng Kang, Yangxue Liu, Qingduan Wang

Eur J Med Chem· August 2015

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Downregulation of MDR1 gene by cepharanthine hydrochloride is related to the activation of c-Jun/JNK in K562/ADR cells.
Li Han, Yafeng Wang, Xiaojuan Guo, Yubing Zhou, Jingmin Zhang, Ning Wang, Qingduan Wang

Biomed Res Int· July 2015

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FNC, a novel nucleoside analogue, blocks invasion of aggressive non-Hodgkin lymphoma cell lines via inhibition of the Wnt/β-catenin signaling pathway.
Yan Zhang, Chen-Ping Wang, Xi-Xi Ding, Ning Wang, Fang Ma, Qing-Duan Wang

Asian Pac J Cancer Prev· June 2015

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Synthesis and biological evaluation of 4-substituted fluoronucleoside analogs for the treatment of hepatitis B virus infection.
Qinghua Yang, Jinfeng Kang, Liyun Zheng, Xue-Jun Wang, Na Wan, Sheng-Qi Wang, Qingduan Wang

J Med Chem· May 2015

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Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice.
Xiao-Lan Qian, Wei Zhang, Ming-Zheng Liu, Yu-Bing Zhou, Jing-Min Zhang, Qing-Duan Wang

Eur J Pharmacol· January 2015

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Quantification of 2'-deoxy-2'-β-fluoro-4'-azidocytidine in rat and dog plasma using liquid chromatography-quadrupole time-of-flight and liquid chromatography-triple quadrupole mass spectrometry: Application to bioavailability and pharmacokinetic studies.
Youmei Peng, Tiefeng Cheng, Lihong Dong, Yuhai Zhang, Xiaojing Chen, Qingduan Wang

J Pharm Biomed Anal· September 2014

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[Expression of CCDC67 mRNA and its role in patients with papillary thyroid carcinoma].
Detao Yin, Jianhui Xu, Yongfei Wang, Hongqiang Li, Yan Zhang, Qingduan Wang

Zhonghua Yi Xue Za Zhi· August 2014

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Novel nucleoside analogue FNC is effective against both wild-type and lamivudine-resistant HBV clinical isolates.
Yubing Zhou, Yan Zhang, Xiaoang Yang, Jing Zhao, Liyun Zheng, Qingduan Wang

Antivir Ther· June 2013

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Anti-hepatitis B virus activity of α-DDB-DU, a novel nucleoside analogue, in vitro and in vivo.
Li-Yun Zheng, Li-Min Zang, Qing-Hua Yang, Wen-Quan Yu, Xian-Zhen Fang, Qing-Duan Wang

Eur J Pharmacol· February 2013

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Anti-hepatitis B virus activities of α-DDB-FNC, a novel nucleoside-biphenyldicarboxylate compound in cells and ducks, and its anti-immunological liver injury effect in mice.
Qinghua Yang, Xuejie Zhao, Limin Zang, Xianzhen Fang, Jing Zhao, Qingduan Wang

Antiviral Res· December 2012

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[Relationship between methylation status of promoter and expression of XAF1 gene in papillary thyroid carcinoma].
De-tao Yin, Guo Chen, Hong-qiang Li, Xiang-yu Zheng, Yong-fei Wang, Qing-duan Wang

Zhonghua Yi Xue Za Zhi· July 2012

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