Publications by authors named "Que T Lambert"

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Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies.
Holly Koblish, Yun-Long Li, Niu Shin, Leslie Hall, Qian Wang, Que T Lambert

PLoS One· December 2018

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Potent Dual BET Bromodomain-Kinase Inhibitors as Value-Added Multitargeted Chemical Probes and Cancer Therapeutics.
Stuart W Ember, Que T Lambert, Norbert Berndt, Steven Gunawan, Muhammad Ayaz

Mol Cancer Ther· June 2017

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The PIM inhibitor AZD1208 synergizes with ruxolitinib to induce apoptosis of ruxolitinib sensitive and resistant JAK2-V617F-driven cells and inhibit colony formation of primary MPN cells.
Lucia Mazzacurati, Que T Lambert, Anuradha Pradhan, Lori N Griner, Dennis Huszar

Oncotarget· November 2015

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Mutations in the transmembrane and juxtamembrane domains enhance IL27R transforming activity.
Que T Lambert, Anuradha Pradhan, J Devon Roll, Gary W Reuther

Biochem J· August 2011

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Transforming JAK1 mutations exhibit differential signalling, FERM domain requirements and growth responses to interferon-γ.
Geoff M Gordon, Que T Lambert, Kenyon G Daniel, Gary W Reuther

Biochem J· December 2010

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Activation of JAK2-V617F by components of heterodimeric cytokine receptors.
Anuradha Pradhan, Que T Lambert, Lori N Griner, Gary W Reuther

J Biol Chem· May 2010

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Activation of Ras proteins by Ras guanine nucleotide releasing protein family members.
Que T Lambert, Gary W Reuther

Methods Enzymol· June 2008

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Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis.
Jiyoung Y Cha, Que T Lambert, Gary W Reuther, Channing J Der

Mol Cancer Res· March 2008

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Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor.
Anuradha Pradhan, Que T Lambert, Gary W Reuther

Proc Natl Acad Sci U S A· November 2007

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RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia.
Gary W Reuther, Que T Lambert, John F Rebhun, Michael A Caligiuri, Lawrence A Quilliam

J Biol Chem· August 2002

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Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism.
John M Lambert, Que T Lambert, Gary W Reuther, Angeliki Malliri, David P Siderovski

Nat Cell Biol· August 2002

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