Publications by authors named "Rachel Carling"

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Patient centric blood sampling and analysis for diagnostics and laboratory medicine.
Neil Spooner, Daniel Baker, Rachel S Carling, Bradley B Collier, Ping Gong

Bioanalysis· October 2025

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Performance properties of filter-paper used in blood spot collection devices for quantitation of phenylalanine.
Annabel Rodham, Christopher von Ruhland, Rachel Carling, Stuart James Moat

Bioanalysis· October 2025

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Simple steps to achieve harmonisation and standardisation of dried blood spot phenylalanine measurements and facilitate consistent management of patients with phenylketonuria.
Rachel S Carling, Zoe Barclay, Nathan Cantley, Nana Ghansah, Sarah L Hogg

Clin Chem Lab Med· June 2025

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Development of an SI traceable value assigned amino acid matrix-matched material to underpin European external quality assessment.
Emily Whyte, Rachel Carling, Simon Cowen, Patrick Sears, Chris Hopley

Anal Bioanal Chem· May 2025

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Urine organic acid metabolomic profiling by gas chromatography mass spectrometry: Assessment of solvent extract evaporation parameters on the recovery of key diagnostic metabolites.
Rachel S Carling, Karolina Witek, Erin C Emmett, Claire Gallagher, Stuart J Moat

Clin Chim Acta· January 2025

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Targeted ultra performance liquid chromatography tandem mass spectrometry procedures for the diagnosis of inborn errors of metabolism: validation through ERNDIM external quality assessment schemes.
Clara Oliva, Angela Arias, Pedro Ruiz-Sala, Judit Garcia-Villoria, Rachel Carling

Clin Chem Lab Med· September 2024

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Consistency in the Assessment of Dried Blood Spot Specimen Size and Quality in U.K. Newborn Screening Laboratories.
Stuart J Moat, James R Bonham, Christine Cavanagh, Margaret Birch, Caroline Griffith, Rachel S Carling

Int J Neonatal Screen· September 2024

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Hereditary tyrosinaemia type 1 in the absence of succinylacetone: 4-oxo 6-hydroxyhepanoate (4OHHA), a putative diagnostic biomarker.
Preeya Rehsi, Karolina Witek, Erin Emmett, Rachel Carling, Charles Turner

JIMD Rep· July 2024

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A high throughput immuno-affinity mass spectrometry method for detection and quantitation of SARS-CoV-2 nucleoprotein in human saliva and its comparison with RT-PCR, RT-LAMP, and lateral flow rapid antigen test.
Dan Lane, Rebecca Allsopp, Christopher W Holmes, Oliver C Slingsby, Rebekah Jukes-Jones, Rachel Carling

Clin Chem Lab Med· May 2024

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Retrospective Review of Positive Newborn Screening Results for Isovaleric Acidemia and Development of a Strategy to Improve the Efficacy of Newborn Screening in the UK.
Rachel S Carling, Katy Hedgethorne, Anupam Chakrapani, Patricia L Hall, Nick Flynn

Int J Neonatal Screen· March 2024

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Incidental Detection of Classical Galactosemia through Newborn Screening for Phenylketonuria: A 10-Year Retrospective Audit to Determine the Efficacy of This Approach.
Nathan W P Cantley, Robert Barski, Helena Kemp, Sarah L Hogg, Hoi Yee Teresa Wu, Rachel S Carling

Int J Neonatal Screen· December 2023

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Investigation of the relationship between phenylalanine in venous plasma and capillary blood using volumetric blood collection devices.
Rachel S Carling, Zoe Barclay, Nathan Cantley, Erin C Emmett, Sarah L Hogg

JIMD Rep· November 2023

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Cross-sectional audit assessing the quality of dried bloodspot specimens received by UK metabolic biochemistry laboratories for the biochemical monitoring of individuals with Phenylketonuria.
Sarah L Hogg, Rachel S Carling, Nathan Wp Cantley, Gillian Hamilton, Philippa Goddard

Ann Clin Biochem· May 2023

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Current State and Innovations in Newborn Screening: Continuing to Do Good and Avoid Harm.
Giancarlo la Marca, Rachel S Carling, Stuart J Moat, Raquel Yahyaoui, Enzo Ranieri

Int J Neonatal Screen· March 2023

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Operation Moonshot: rapid translation of a SARS-CoV-2 targeted peptide immunoaffinity liquid chromatography-tandem mass spectrometry test from research into routine clinical use.
Jenny Hällqvist, Dan Lane, Andrew Shapanis, Kayleigh Davis, Wendy E Heywood, Rachel S Carling

Clin Chem Lab Med· January 2023

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Automation of tacrolimus measurement on volumetric absorptive microsampling devices by tandem mass spectrometry.
Rachel S Carling, Catharine John, Erin C Emmett, Donna Austin, Colin Hastie

Bioanalysis· December 2022

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Evaluation of volumetric blood collection devices for the measurement of phenylalanine and tyrosine to monitor patients with phenylketonuria.
Rachel S Carling, Erin C Emmett, Stuart J Moat

Clin Chim Acta· October 2022

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Improving Harmonization and Standardization of Expanded Newborn Screening Results by Optimization of the Legacy Flow Injection Analysis Tandem Mass Spectrometry Methods and Application of a Standardized Calibration Approach.
Rachel S Carling, Emily Whyte, Catharine John, Rachelle Garstone, Philippa Goddard

Clin Chem· July 2022

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Processing of positive newborn screening results: a qualitative exploration of current practice in England.
Jane Chudleigh, Holly Chinnery, Pru Holder, Rachel S Carling, Kevin Southern

BMJ Open· December 2020

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Evaluation of a Common Internal Standard Material to Reduce Inter-Laboratory Variation and Ensure the Quality, Safety and Efficacy of Expanded Newborn Screening Results When Using Flow Injection Analysis Tandem Mass Spectrometry with Internal Calibration.
Rachel S Carling, Catharine John, Philippa Goddard, Caroline Griffith, Simon Cowen

Int J Neonatal Screen· November 2020

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A Machine Learning Approach for the Automated Interpretation of Plasma Amino Acid Profiles.
Edmund H Wilkes, Erin Emmett, Luisa Beltran, Gary M Woodward, Rachel S Carling

Clin Chem· September 2020

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Validation of a liquid chromatography tandem mass spectrometry method for the simultaneous determination of hydroxychloroquine and metabolites in human whole blood.
Donna Austin, Catharine John, Beverley J Hunt, Rachel S Carling

Clin Chem Lab Med· September 2020

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Challenging the status quo: A comparison of ion exchange chromatography with liquid chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry methods for the measurement of amino acids in human plasma.
Rachel S Carling, Benjamin Ac McDonald, Donna Austin, Deborah Burden, Joana Correia

Ann Clin Biochem· July 2020

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Use of Dried Blood Spot Specimens to Monitor Patients with Inherited Metabolic Disorders.
Stuart J Moat, Roanna S George, Rachel S Carling

Int J Neonatal Screen· June 2020

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Validation of a rapid, comprehensive and clinically relevant amino acid profile by underivatised liquid chromatography tandem mass spectrometry.
Rachel S Carling, Kate John, Richard Churchus, Charles Turner, R Neil Dalton

Clin Chem Lab Med· April 2020

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