Publications by authors named "Rachel Codd"

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Directing the chemoenzymatic assembly of desferrioxamine B as a single product using -butoxycarbonyl-protected substrates.
Todd E Markham, Athavan Sresutharsan, Callum A Rosser, Rachel Codd

Org Biomol Chem· July 2025

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The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response.
Ruby Pandher, Chengyuan Xue, Laura D Gamble, Giorgio Milazzo, Simone Di Giacomo, Rachel Codd

Proc Natl Acad Sci U S A· June 2025

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Copper supplementation mitigates Parkinson-like wild-type SOD1 pathology and nigrostriatal degeneration in a novel mouse model.
Benjamin D Rowlands, Benjamin G Trist, Connor Karozis, Greta Schaffer, David Mor, Rachel Codd

Acta Neuropathol Commun· June 2025

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Carboxamide-Bearing Panobinostat Analogues Designed To Interact with E103-D104 at the Cavity Opening of Class I HDAC Isoforms.
Callum A Rosser, Samuel V Feeney, Lukas Roth, David E Hibbs, Michael P Gotsbacher, Rachel Codd

ACS Med Chem Lett· February 2025

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An elastic siderophore synthetase and rubbery substrates assemble multimeric linear and macrocyclic hydroxamic acid metal chelators.
Kate P Nolan, Callum A Rosser, James L Wood, Josep Font, Athavan Sresutharsan, Rachel Codd

Chem Sci· January 2025

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The production of siderophore analogues using precursor-directed biosynthesis.
Tomas Richardson-Sanchez, Thomas J Telfer, Cho Z Soe, Kate P Nolan, Michael P Gotsbacher, Rachel Codd

Methods Enzymol· August 2024

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A first-in-class dual-chelator theranostic agent designed for use with imaging-therapy radiometal pairs of different elements.
James L Wood, Saikat Ghosh, Zachary H Houston, Nicholas L Fletcher, James Humphries, Rachel Codd

Chem Sci· July 2024

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A Mild and Modular Approach to the Total Synthesis of Desferrioxamine B.
Todd E Markham, Rachel Codd

J Org Chem· April 2024

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Reduction-cleavable desferrioxamine B pulldown system enriches Ni(ii)-superoxide dismutase from a proteome.
Jenny Ni, James L Wood, Melanie Y White, Norbert Lihi, Todd E Markham, Rachel Codd

RSC Chem Biol· November 2023

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A first-in-human study of [Ga]Ga-CDI: a positron emitting radiopharmaceutical for imaging tumour cell death.
Ivan Ho Shon, Thomas Hennessy, Jennifer Guille, Michael P Gotsbacher, Angelina J Lay, Rachel Codd

Eur J Nucl Med Mol Imaging· October 2022

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Adding a diazo-transfer reagent to culture to generate secondary metabolite probes for click chemistry.
Michael P Gotsbacher, Rachel Codd

Methods Enzymol· April 2022

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Acetyl-CoA-Mediated Post-Biosynthetic Modification of Desferrioxamine B Generates - and N--Acetylated Isomers Controlled by a pH Switch.
Kate P Nolan, Josep Font, Athavan Sresutharsan, Michael P Gotsbacher, Christopher J M Brown, Rachel Codd

ACS Chem Biol· February 2022

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Directing macrocyclic architecture using iron(III)-, gallium(III)-, or zirconium(IV)-assisted ring closure of linear dimeric endo-hydroxamic acid ligands.
Christopher J M Brown, Rachel Codd

J Inorg Biochem· March 2021

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Immobilized Metal Affinity Chromatography as a Drug Discovery Platform for Metalloenzyme Inhibitors.
Lukas Roth, Michael P Gotsbacher, Rachel Codd

J Med Chem· October 2020

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Azido-Desferrioxamine Siderophores as Functional Click-Chemistry Probes Generated in Culture upon Adding a Diazo-Transfer Reagent.
Michael P Gotsbacher, Rachel Codd

Chembiochem· May 2020

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Preparation of a Dithiol-Reactive Probe for PET Imaging of Cell Death.
Ivan Ho Shon, Michael P Gotsbacher, Jennifer Guille, Divesh Kumar, Rachel Codd

Methods Mol Biol· November 2019

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-Hydroxamic Acid Monomers for the Assembly of a Suite of Non-native Dimeric Macrocyclic Siderophores Using Metal-Templated Synthesis.
Christopher J M Brown, Michael P Gotsbacher, Jason P Holland, Rachel Codd

Inorg Chem· October 2019

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Exploring hydroxamic acid inhibitors of HDAC1 and HDAC2 using small molecule tools and molecular or homology modelling.
Lydia Daniel, Michael P Gotsbacher, Tomas Richardson-Sanchez, William Tieu, Rachel Codd

Bioorg Med Chem Lett· September 2019

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Analogues of desferrioxamine B (DFOB) with new properties and new functions generated using precursor-directed biosynthesis.
Thomas J Telfer, Tomas Richardson-Sanchez, Michael P Gotsbacher, Kate P Nolan, William Tieu, Rachel Codd

Biometals· June 2019

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The chemical biology and coordination chemistry of putrebactin, avaroferrin, bisucaberin, and alcaligin.
Rachel Codd, Cho Zin Soe, Amalie A H Pakchung, Athavan Sresutharsan, Christopher J M Brown

J Biol Inorg Chem· October 2018

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Fluorinated Analogues of Desferrioxamine B from Precursor-Directed Biosynthesis Provide New Insight into the Capacity of DesBCD.
Thomas J Telfer, Rachel Codd

ACS Chem Biol· September 2018

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Engineering a cleavable disulfide bond into a natural product siderophore using precursor-directed biosynthesis.
Tomas Richardson-Sanchez, Rachel Codd

Chem Commun (Camb)· August 2018

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Advances in the Chemical Biology of Desferrioxamine B.
Rachel Codd, Tomas Richardson-Sanchez, Thomas J Telfer, Michael P Gotsbacher

ACS Chem Biol· January 2018

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Dimeric and trimeric homo- and heteroleptic hydroxamic acid macrocycles formed using mixed-ligand Fe(III)-based metal-templated synthesis.
Athavan Sresutharsan, William Tieu, Tomas Richardson-Sanchez, Cho Zin Soe, Rachel Codd

J Inorg Biochem· December 2017

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Exploiting the biosynthetic machinery of Streptomyces pilosus to engineer a water-soluble zirconium(iv) chelator.
Tomas Richardson-Sanchez, William Tieu, Michael P Gotsbacher, Thomas J Telfer, Rachel Codd

Org Biomol Chem· July 2017

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