Publications by authors named "Rachel D Edgar"

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Single-cell atlas of human pediatric liver reveals age-related hepatic gene signatures.
Rachel D Edgar, Diana Nakib, Damra Camat, Sai Chung, Patricia Lumanto

Hepatol Commun· November 2025

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Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn's Disease.
Thomas W Dennison, Rachel D Edgar, Felicity Payne, Komal M Nayak, Alexander D B Ross

Gut· August 2024

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Culture-Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids.
Rachel D Edgar, Francesca Perrone, April R Foster, Felicity Payne, Sophia Lewis

Cell Mol Gastroenterol Hepatol· November 2022

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Impacts of the COVID-19 pandemic on hepatitis C elimination in Canada: Where do we go from here?
Jawairia Atif, Sasha Tejna Persaud Udhesister, Mohamed N Abdelnabi, Simmone D'Souza, Jui-Hsia Hung, Rachel D Edgar

Can Liver J· November 2022

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Immune cell type and DNA methylation vary with reproductive status in women: possible pathways for costs of reproduction.
Calen P Ryan, Meaghan J Jones, Rachel D Edgar, Nanette R Lee, Michael S Kobor

Evol Med Public Health· February 2022

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Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults.
Rym Ben-Othman, Bing Cai, Aaron C Liu, Natallia Varankovich, Daniel He, Rachel D Edgar

Front Immunol· June 2021

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Multi-Omic Data Integration Allows Baseline Immune Signatures to Predict Hepatitis B Vaccine Response in a Small Cohort.
Casey P Shannon, Travis M Blimkie, Rym Ben-Othman, Nicole Gladish, Nelly Amenyogbe, Rachel D Edgar

Front Immunol· June 2021

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Transcription and DNA Methylation Patterns of Blood-Derived CD8 T Cells Are Associated With Age and Inflammatory Bowel Disease But Do Not Predict Prognosis.
Marco Gasparetto, Felicity Payne, Komal Nayak, Judith Kraiczy, Claire Glemas, Rachel D Edgar

Gastroenterology· January 2021

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The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells.
Lisa M McEwen, Kieran J O'Donnell, Megan G McGill, Rachel D Edgar, Meaghan J Jones

Proc Natl Acad Sci U S A· September 2020

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The biological embedding of early-life socioeconomic status and family adversity in children's genome-wide DNA methylation.
Nicole R Bush, Rachel D Edgar, Mina Park, Julia L MacIsaac, Lisa M McEwen

Epigenomics· November 2018

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Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array.
Lisa M McEwen, Meaghan J Jones, David Tse Shen Lin, Rachel D Edgar, Lucas T Husquin

Clin Epigenetics· October 2018

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Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region.
Lisa M McEwen, Alexander M Morin, Rachel D Edgar, Julia L MacIsaac, Meaghan J Jones

Epigenetics Chromatin· January 2018

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An empirically driven data reduction method on the human 450K methylation array to remove tissue specific non-variable CpGs.
Rachel D Edgar, Meaghan J Jones, Wendy P Robinson, Michael S Kobor

Clin Epigenetics· December 2017

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Adjusting for Cell Type Composition in DNA Methylation Data Using a Regression-Based Approach.
Meaghan J Jones, Sumaiya A Islam, Rachel D Edgar, Michael S Kobor

Methods Mol Biol· October 2017

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Maternal prenatal anxiety and child COMT genotype predict working memory and symptoms of ADHD.
Kieran J O'Donnell, Vivette Glover, Jari Lahti, Marius Lahti, Rachel D Edgar

PLoS One· September 2017

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DNA methylation signature of human fetal alcohol spectrum disorder.
Elodie Portales-Casamar, Alexandre A Lussier, Meaghan J Jones, Julia L MacIsaac, Rachel D Edgar

Epigenetics Chromatin· June 2016

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