Publications by authors named "Rachel Heath"

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Critically appraising the cass report: methodological flaws and unsupported claims.
Chris Noone, Alex Southgate, Alex Ashman, Éle Quinn, David Comer, Duncan Shrewsbury, Florence Ashley, Jo Hartland, Joanna Paschedag, John Gilmore

May 2025

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An engineered aldolase enables the biocatalytic synthesis of 2'-functionalized nucleoside analogues.
Matthew Willmott, William Finnigan, William R Birmingham, Sasha R Derrington, Rachel S Heath

Nat Synth· November 2024

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Bifunctional Imine Reductase Cascades for the Synthesis of Saturated -Heterocycles.
Jeremy I Ramsden, Bruna Zucoloto da Costa, Rachel S Heath, James R Marshall, Sasha R Derrington

ACS Catal· October 2024

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RetroBioCat Database: A Platform for Collaborative Curation and Automated Meta-Analysis of Biocatalysis Data.
William Finnigan, Max Lubberink, Lorna J Hepworth, Joan Citoler, Ashley P Mattey, Rachel S Heath

ACS Catal· September 2023

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Structure-Based Design of Small Imine Reductase Panels for Target Substrates.
Yuqi Yu, Arnau Rué Casamajo, William Finnigan, Christian Schnepel, Rhys Barker, Rachel S Heath

ACS Catal· September 2023

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Mind your language: how medical parlance can undermine the therapeutic relationship.
Stuart N Cohen, Rachel J Heath

Clin Exp Dermatol· July 2023

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Synthesis of Stereoenriched Piperidines via Chemo-Enzymatic Dearomatization of Activated Pyridines.
Vanessa Harawa, Thomas W Thorpe, James R Marshall, Jack J Sangster, Amelia K Gilio, Rachel S Heath

J Am Chem Soc· November 2022

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Deracemisation and stereoinversion by a nanoconfined bidirectional enzyme cascade: dual control by electrochemistry and selective metal ion activation.
Beichen Cheng, Rachel S Heath, Nicholas J Turner, Fraser A Armstrong, Clare F Megarity

Chem Commun (Camb)· October 2022

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A Nanoconfined Four-Enzyme Cascade Simultaneously Driven by Electrical and Chemical Energy, with Built-in Rapid, Confocal Recycling of NADP(H) and ATP.
Clare F Megarity, Thomas R I Weald, Rachel S Heath, Nicholas J Turner, Fraser A Armstrong

ACS Catal· August 2022

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An Engineered Cholesterol Oxidase Catalyses Enantioselective Oxidation of Non-steroidal Secondary Alcohols.
Rachel S Heath, Jack J Sangster, Nicholas J Turner

Chembiochem· April 2022

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Multifunctional biocatalyst for conjugate reduction and reductive amination.
Thomas W Thorpe, James R Marshall, Vanessa Harawa, Rebecca E Ruscoe, Anibal Cuetos, Rachel S Heath

Nature· April 2022

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The beauty of biocatalysis: sustainable synthesis of ingredients in cosmetics.
Rachel S Heath, Rebecca E Ruscoe, Nicholas J Turner

Nat Prod Rep· February 2022

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Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination.
James R Marshall, Peiyuan Yao, Sarah L Montgomery, James D Finnigan, Thomas W Thorpe, Rachel S Heath

Nat Chem· February 2021

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Natural heterogeneous catalysis with immobilised oxidase biocatalysts.
Ashley P Mattey, Jack J Sangster, Jeremy I Ramsden, Christopher Baldwin, William R Birmingham, Rachel S Heath

RSC Adv· May 2020

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Characterization of imine reductases in reductive amination for the exploration of structure-activity relationships.
Sarah L Montgomery, Ahir Pushpanath, Rachel S Heath, James R Marshall, Ulrike Klemstein

Sci Adv· May 2020

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Imine Reductases, Reductive Aminases, and Amine Oxidases for the Synthesis of Chiral Amines: Discovery, Characterization, and Synthetic Applications.
Sebastian C Cosgrove, Agata Brzezniak, Scott P France, Jeremy I Ramsden, Juan Mangas-Sanchez, Rachel S Heath

Methods Enzymol· June 2019

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Electrocatalytic Volleyball: Rapid Nanoconfined Nicotinamide Cycling for Organic Synthesis in Electrode Pores.
Clare F Megarity, Bhavin Siritanaratkul, Rachel S Heath, Lei Wan, Giorgio Morello

Angew Chem Int Ed Engl· April 2019

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An Engineered Alcohol Oxidase for the Oxidation of Primary Alcohols.
Rachel S Heath, William R Birmingham, Matthew P Thompson, Andreas Taglieber, Laurent Daviet

Chembiochem· January 2019

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Biocatalytic N-Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades.
Jeremy I Ramsden, Rachel S Heath, Sasha R Derrington, Sarah L Montgomery, Juan Mangas-Sanchez

J Am Chem Soc· January 2019

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Biocatalytic approaches to a key building block for the anti-thrombotic agent ticagrelor.
Katharina G Hugentobler, Humera Sharif, Marcello Rasparini, Rachel S Heath, Nicholas J Turner

Org Biomol Chem· September 2016

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Detecting Nonlinearity and Edge-of-Chaos Phenomena in Ordinal Data.
Rachel Heath

Nonlinear Dynamics Psychol Life Sci· July 2015

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Immobilised whole-cell recombinant monoamine oxidase biocatalysis.
Petra Zajkoska, Michal Rosenberg, Rachel Heath, Kirk J Malone, Radek Stloukal

Appl Microbiol Biotechnol· February 2015

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What happens after prothrombin complex concentrate administration?
Sarah Horton, Rachel Heath, Anthony Houghton, Vanessa Martlew, Jecko Thachil

Eur J Intern Med· April 2013

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A very elevated D-dimer level may potentially be useful.
Rachel Heath, Sarah Horton, Vanessa Martlew, Jecko Thachil

Eur J Intern Med· March 2013

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Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion.
Deema Hussein, Wiyada Punjaruk, Lisa C D Storer, Lucy Shaw, Ramadhan Othman, Rachel Heath

Neuro Oncol· January 2011

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