Publications by authors named "Rachel Howarth"

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Food Insecurity Is Highly Prevalent Amongst Patients With Chronic Liver Disease in Northern England: A Cross-Sectional Analysis.
Rachel Howarth, Thomas Crame, Stuart McPherson, Quentin M Anstee, Laura Haigh

J Hum Nutr Diet· December 2025

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Bioengineering of a tumour-stroma 3D-tumouroid co-culture model of hypopharyngeal cancer.
Santu Saha, Rachel Howarth, Sweta Sharma-Saha, Charles Kelly

Biol Open· May 2023

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Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma: the role of cytoplasmic PIN1 upregulation.
Bassier Zadran, Praveen Dhondurao Sudhindar, Daniel Wainwright, Yvonne Bury, Saimir Luli, Rachel Howarth

Br J Cancer· March 2023

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SHOX Whole Gene Duplications Are Overrepresented in SHOX Haploinsufficiency Phenotype Cohorts.
David J Bunyan, James I Hobbs, Philippa J Duncan-Flavell, Rachel J Howarth, Sarah Beal

Cytogenet Genome Res· March 2023

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Simultaneous targeting of glycolysis and oxidative phosphorylation as a therapeutic strategy to treat diffuse large B-cell lymphoma.
Richard A Noble, Huw Thomas, Yan Zhao, Lili Herendi, Rachel Howarth

Br J Cancer· September 2022

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Determining the Potential of DNA Damage Response (DDR) Inhibitors in Cervical Cancer Therapy.
Santu Saha, Stuart Rundle, Ioannis C Kotsopoulos, Jacob Begbie, Rachel Howarth

Cancers (Basel)· September 2022

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Apparent Homozygosity for a gr/gr AZFc Deletion in A 47,XYY Man with Oligozoospermia and Secondary Infertility.
David J Bunyan, Mili Saran, James I Hobbs, David J Anderson, Philippa J Duncan-Flavell, Rachel J Howarth

J Reprod Infertil· January 2022

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HCV Activates Somatic L1 Retrotransposition-A Potential Hepatocarcinogenesis Pathway.
Praveen D Sudhindar, Daniel Wainwright, Santu Saha, Rachel Howarth, Misti McCain

Cancers (Basel)· October 2021

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Integration of computer-aided automated analysis algorithms in the development and validation of immunohistochemistry biomarkers in ovarian cancer.
Lucy Gentles, Rachel Howarth, Won Ji Lee, Sweta Sharma-Saha, Angela Ralte

J Clin Pathol· July 2021

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Modulation of the Acetylcholine Receptor Clustering Pathway Improves Neuromuscular Junction Structure and Muscle Strength in a Mouse Model of Congenital Myasthenic Syndrome.
Sally Spendiff, Rachel Howarth, Grace McMacken, Tracey Davey, Kaitlyn Quinlan

Front Mol Neurosci· December 2020

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Screening of a large Rubinstein-Taybi cohort identified many novel variants and emphasizes the importance of the CREBBP histone acetyltransferase domain.
Esther Cross, Philippa J Duncan-Flavell, Rachel J Howarth, James I Hobbs, Nicholas Simon Thomas

Am J Med Genet A· November 2020

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Screening of a large PAX6 cohort identified many novel variants and emphasises the importance of the paired and homeobox domains.
Esther Cross, Philippa J Duncan-Flavell, Rachel J Howarth, Richard O Crooks, N Simon Thomas

Eur J Med Genet· July 2020

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FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis.
Jack Leslie, Ben Jm Millar, Alicia Del Carpio Pons, Rachel A Burgoyne, Joseph D Frost, Rachel Howarth

JCI Insight· February 2020

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Salbutamol modifies the neuromuscular junction in a mouse model of ColQ myasthenic syndrome.
Grace M McMacken, Sally Spendiff, Roger G Whittaker, Emily O'Connor, Rachel M Howarth

Hum Mol Genet· July 2019

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noise warning devices cause a sustained reduction in ambient noise in adult critical care.
Nicholas Russell Plummer, Anna Herbert, James Edward Blundell, Rachel Howarth, Jacqueline Baldwin

J Intensive Care Soc· May 2019

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The NF-κB1 is a key regulator of acute but not chronic renal injury.
Amy Fearn, Gerhard R Situmorang, Christopher Fox, Fiona Oakley, Rachel Howarth

Cell Death Dis· June 2017

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Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury.
Pasquale Cocchiaro, Christopher Fox, Nicholas W Tregidgo, Rachel Howarth, Katrina M Wood

Sci Rep· June 2016

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Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease.
Christopher Fox, Pasquale Cocchiaro, Fiona Oakley, Rachel Howarth, Krystena Callaghan

Sci Rep· February 2016

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Alcohol directly stimulates epigenetic modifications in hepatic stellate cells.
Agata Page, Pier P Paoli, Stephen J Hill, Rachel Howarth, Raymond Wu

J Hepatol· February 2015

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A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse.
Anna Moles, Lindsay Murphy, Caroline L Wilson, Jayashree Bagchi Chakraborty, Christopher Fox, Rachel Howarth

J Hepatol· April 2014

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Genetic analysis of chromosome 11p13 and the PAX6 gene in a series of 125 cases referred with aniridia.
David O Robinson, Rachel J Howarth, Kathleen A Williamson, Veronica van Heyningen, Sarah J Beal

Am J Med Genet A· March 2008

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Application of dHPLC for mutation detection of the fibrillin-1 gene for the diagnosis of Marfan syndrome in a National Health Service Laboratory.
Rachel Howarth, Catharina Yearwood, John F Harvey

Genet Test· September 2007

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Ocular findings in Gillespie-like syndrome: association with a new PAX6 mutation.
Benjamin H Ticho, Clair Hilchie-Schmidt, Robert T Egel, Elias I Traboulsi, Rachel J Howarth

Ophthalmic Genet· December 2006

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