Publications by authors named "Rachel Mayfield"

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Myocardial transcriptomic and proteomic landscapes across the menopausal continuum in a murine model of chemically induced accelerated ovarian failure.
Marissa A Lopez-Pier, Vito A Marino, Andrea C Vazquez-Loreto, Rinku S Skaria, Danielle K Cannon, Rachel Mayfield

Physiol Genomics· July 2025

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Leiomodin 2 neonatal dilated cardiomyopathy mutation results in altered actin gene signatures and cardiomyocyte dysfunction.
Jessika B Iwanski, Christopher T Pappas, Rachel M Mayfield, Gerrie P Farman, Rebecca Ahrens-Nicklas

NPJ Regen Med· September 2024

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Human disease-causing mutations result in loss of leiomodin 2 through nonsense-mediated mRNA decay.
Christopher T Pappas, Rachel M Mayfield, Ava E Dickerson, Lei Mi-Mi, Carol C Gregorio

PLoS Genet· May 2024

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Lmod2 is necessary for effective skeletal muscle contraction.
Tania M Larrinaga, Gerrie P Farman, Rachel M Mayfield, Michaela Yuen, Rebecca C Ahrens-Nicklas

Sci Adv· March 2024

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A nemaline myopathy-linked mutation inhibits the actin-regulatory functions of tropomodulin and leiomodin.
Lauren E Schultz, Mert Colpan, Garry E Smith, Rachel M Mayfield, Tania M Larrinaga

Proc Natl Acad Sci U S A· November 2023

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EVL is a novel focal adhesion protein involved in the regulation of cytoskeletal dynamics and vascular permeability.
Joseph B Mascarenhas, Amir A Gaber, Tania M Larrinaga, Rachel Mayfield, Stefanie Novak

Pulm Circ· October 2021

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In vivo elongation of thin filaments results in heart failure.
Lei Mi-Mi, Gerrie P Farman, Rachel M Mayfield, Joshua Strom, Miensheng Chu

PLoS One· April 2020

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Disruption of cardiac thin filament assembly arising from a mutation in : A novel mechanism of neonatal dilated cardiomyopathy.
Rebecca C Ahrens-Nicklas, Christopher T Pappas, Gerrie P Farman, Rachel M Mayfield, Tania M Larrinaga

Sci Adv· September 2019

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Cardiac-specific knockout of Lmod2 results in a severe reduction in myofilament force production and rapid cardiac failure.
Christopher T Pappas, Gerrie P Farman, Rachel M Mayfield, John P Konhilas, Carol C Gregorio

J Mol Cell Cardiol· September 2018

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The N-terminal tropomyosin- and actin-binding sites are important for leiomodin 2's function.
Thu Ly, Natalia Moroz, Christopher T Pappas, Stefanie M Novak, Dmitri Tolkatchev, Rachel M Mayfield

Mol Biol Cell· August 2016

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Liver Kinase B1 complex acts as a novel modifier of myofilament function and localizes to the Z-disk in cardiac myocytes.
Samantha M Behunin, Marissa A Lopez-Pier, Rachel M Mayfield, Christiane A Danilo, Yulia Lipovka

Arch Biochem Biophys· July 2016

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Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality.
Christopher T Pappas, Rachel M Mayfield, Christine Henderson, Nima Jamilpour, Cathleen Cover

Proc Natl Acad Sci U S A· November 2015

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