Publications by authors named "Rachel Ngo"

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Discovery of AMG 193, an MTA-Cooperative PRMT5 Inhibitor for the Treatment of -Deleted Cancers.
Liping H Pettus, Matthew Bourbeau, Nuria A Tamayo, Albert Amegadzie, Diane Beylkin, Rachel Ngo

J Med Chem· April 2025

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From DNA-Encoded Library Screening to : An MTA-Cooperative PRMT5 Inhibitor with Potent Oral In Vivo Efficacy.
Ian Sarvary, Mikkel Vestergaard, Loris Moretti, Jan Andersson, Jorge Peiró Cadahía, Rachel Ngo

J Med Chem· March 2025

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Case study: lessons learned from a community-based early frailty intervention programme in Singapore.
Kamala Priya Jayaprakash, Rachel Ngo, Elianna Lee, Pey Ling Chng, Hengky Lee

Front Public Health· November 2024

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Creating a more strategic small molecule biophysical hit characterization workflow.
Christopher Fotsch, Debaleena Basu, Ryan Case, Qing Chen, Pratibha C Koneru, Rachel Ngo

SLAS Discov· June 2024

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Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor for treating acute myeloid leukemia.
Kathleen Keegan, Cong Li, Zhihong Li, Ji Ma, Mark Ragains, Rachel Ngo

Mol Cancer Ther· April 2014

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Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3.
Zhihong Li, Xianghong Wang, John Eksterowicz, Michael W Gribble, Grace Q Alba, Rachel Ngo

J Med Chem· April 2014

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Development of a time-resolved fluorescence resonance energy transfer assay for cyclin-dependent kinase 4 and identification of its ATP-noncompetitive inhibitors.
Mei-Chu Lo, Rachel Ngo, Kang Dai, Cong Li, Lingming Liang

Anal Biochem· February 2012

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