Publications by authors named "Rachel Piddock"

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Biallelic TET2 mutations confer sensitivity to 5'-azacitidine in acute myeloid leukemia.
Friedrich Stölzel, Sarah E Fordham, Devi Nandana, Wei-Yu Lin, Helen Blair, Rachel Piddock

JCI Insight· January 2023

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Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia.
Wei-Yu Lin, Sarah E Fordham, Nicola Sunter, Claire Elstob, Thahira Rahman, Rachel Piddock

Nat Commun· January 2021

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CD38-Driven Mitochondrial Trafficking Promotes Bioenergetic Plasticity in Multiple Myeloma.
Christopher R Marlein, Rachel E Piddock, Jayna J Mistry, Lyubov Zaitseva, Charlotte Hellmich

Cancer Res· May 2019

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Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment.
Amina M Abdul-Aziz, Yu Sun, Charlotte Hellmich, Christopher R Marlein, Jayna Mistry, Rachel E Piddock

Blood· January 2019

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PGC-1α driven mitochondrial biogenesis in stromal cells underpins mitochondrial trafficking to leukemic blasts.
Christopher R Marlein, Lyubov Zaitseva, Rachel E Piddock, Livia Raso-Barnett, Michael A Scott

Leukemia· September 2018

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HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia.
Amina M Abdul-Aziz, Manar S Shafat, Yu Sun, Christopher R Marlein, Rachel E Piddock

Oncogene· May 2018

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Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC.
Rachel E Piddock, Christopher R Marlein, Amina Abdul-Aziz, Manar S Shafat, Martin J Auger

J Hematol Oncol· May 2018

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NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts.
Christopher R Marlein, Lyubov Zaitseva, Rachel E Piddock, Stephen D Robinson, Dylan R Edwards

Blood· October 2017

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Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment.
Manar S Shafat, Thomas Oellerich, Sebastian Mohr, Stephen D Robinson, Dylan R Edwards, Rachel E Piddock

Blood· March 2017

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The Role of PI3K Isoforms in Regulating Bone Marrow Microenvironment Signaling Focusing on Acute Myeloid Leukemia and Multiple Myeloma.
Rachel E Piddock, Kristian M Bowles, Stuart A Rushworth

Cancers (Basel)· March 2017

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Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection.
Genevra Pillinger, Niamh V Loughran, Rachel E Piddock, Manar S Shafat, Lyubov Zaitseva

Oncotarget· June 2016

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Activity of Bruton's tyrosine-kinase inhibitor ibrutinib in patients with CD117-positive acute myeloid leukaemia: a mechanistic study using patient-derived blast cells.
Stuart A Rushworth, Genevra Pillinger, Amina Abdul-Aziz, Rachel Piddock, Manar S Shafat

Lancet Haematol· May 2015

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