Publications by authors named "Rachel R Chen"

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Comparative genomics and transcriptomics analysis-guided metabolic engineering of Propionibacterium acidipropionici for improved propionic acid production.
Ningzi Guan, Bin Du, Jianghua Li, Hyun-Dong Shin, Rachel R Chen, Guocheng Du, Jian Chen

Biotechnol Bioeng· February 2018

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Improved production of propionic acid in Propionibacterium jensenii via combinational overexpression of glycerol dehydrogenase and malate dehydrogenase from Klebsiella pneumoniae.
Long Liu, Xin Zhuge, Hyun-Dong Shin, Rachel R Chen, Jianghua Li, Guocheng Du, Jian Chen

Appl Environ Microbiol· April 2015

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Recent advances in discovery, heterologous expression, and molecular engineering of cyclodextrin glycosyltransferase for versatile applications.
Ruizhi Han, Jianghua Li, Hyun-Dong Shin, Rachel R Chen, Guocheng Du, Jian Chen

Biotechnol Adv· November 2014

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Understanding of how Propionibacterium acidipropionici respond to propionic acid stress at the level of proteomics.
Ningzi Guan, Hyun-dong Shin, Rachel R Chen, Jianghua Li, Long Liu, Guocheng Du, Jian Chen

Sci Rep· November 2014

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Fusion of self-assembling amphipathic oligopeptides with cyclodextrin glycosyltransferase improves 2-O-D-glucopyranosyl-L-ascorbic acid synthesis with soluble starch as the glycosyl donor.
Ruizhi Han, Jianghua Li, Hyun-dong Shin, Rachel R Chen, Long Liu, Guocheng Du, Jian Chen

Appl Environ Microbiol· August 2014

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Modular pathway engineering of Bacillus subtilis for improved N-acetylglucosamine production.
Yanfeng Liu, Yanqiu Zhu, Jianghua Li, Hyun-dong Shin, Rachel R Chen, Guocheng Du, Jian Chen

Metab Eng· May 2014

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In silico rational design and systems engineering of disulfide bridges in the catalytic domain of an alkaline α-amylase from Alkalimonas amylolytica to improve thermostability.
Long Liu, Zhuangmei Deng, Haiquan Yang, Jianghua Li, Hyun-dong Shin, Rachel R Chen, Guocheng Du, Jian Chen

Appl Environ Microbiol· February 2014

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Comparative analysis of heterologous expression, biochemical characterization optimal production of an alkaline α-amylase from alkaliphilic Alkalimonas amylolytica in Escherichia coli and Pichia pastoris.
Haiquan Yang, Long Liu, Hyun-dong Shin, Rachel R Chen, Jianghua Li, Guocheng Du, Jian Chen

Biotechnol Prog· January 2014

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How to achieve high-level expression of microbial enzymes: strategies and perspectives.
Long Liu, Haiquan Yang, Hyun-dong Shin, Rachel R Chen, Jianghua Li, Guocheng Du, Jian Chen

Bioengineered· January 2014

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Bioconversion of l-glutamic acid to α-ketoglutaric acid by an immobilized whole-cell biocatalyst expressing l-amino acid deaminase from Proteus mirabilis.
Gazi Sakir Hossain, Jianghua Li, Hyun-dong Shin, Rachel R Chen, Guocheng Du, Jian Chen

J Biotechnol· January 2014

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Iterative saturation mutagenesis of -6 subsite residues in cyclodextrin glycosyltransferase from Paenibacillus macerans to improve maltodextrin specificity for 2-O-D-glucopyranosyl-L-ascorbic acid synthesis.
Ruizhi Han, Long Liu, Hyun-Dong Shin, Rachel R Chen, Jianghua Li, Guocheng Du, Jian Chen

Appl Environ Microbiol· December 2013

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Integrating terminal truncation and oligopeptide fusion for a novel protein engineering strategy to improve specific activity and catalytic efficiency: alkaline α-amylase as a case study.
Haiquan Yang, Long Liu, Hyun-dong Shin, Rachel R Chen, Jianghua Li, Guocheng Du, Jian Chen

Appl Environ Microbiol· October 2013

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Pathway engineering of Bacillus subtilis for microbial production of N-acetylglucosamine.
Yanfeng Liu, Long Liu, Hyun-dong Shin, Rachel R Chen, Jianghua Li, Guocheng Du, Jian Chen

Metab Eng· September 2013

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Biosynthesis of homoeriodictyol from eriodictyol by flavone 3'-O-methyltransferase from recombinant Yarrowia lioplytica: Heterologous expression, biochemical characterization, and optimal transformation.
Qingtao Liu, Long Liu, Jingwen Zhou, Hyun-Dong Shin, Rachel R Chen, Guocheng Du, Jian Chen

J Biotechnol· September 2013

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Development of a Propionibacterium-Escherichia coli shuttle vector for metabolic engineering of Propionibacterium jensenii, an efficient producer of propionic acid.
Xin Zhuge, Long Liu, Hyun-dong Shin, Rachel R Chen, Jianghua Li, Guocheng Du, Jian Chen

Appl Environ Microbiol· August 2013

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Systems-level understanding of how Propionibacterium acidipropionici respond to propionic acid stress at the microenvironment levels: mechanism and application.
Ningzi Guan, Long Liu, Hyun-Dong Shin, Rachel R Chen, Juan Zhang, Guocheng Du, Jian Chen

J Biotechnol· August 2013

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Site-saturation engineering of lysine 47 in cyclodextrin glycosyltransferase from Paenibacillus macerans to enhance substrate specificity towards maltodextrin for enzymatic synthesis of 2-O-D-glucopyranosyl-L-ascorbic acid (AA-2G).
Ruizhi Han, Long Liu, Hyun-dong Shin, Rachel R Chen, Guocheng Du, Jian Chen

Appl Microbiol Biotechnol· July 2013

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Improving maltodextrin specificity for enzymatic synthesis of 2-O-d-glucopyranosyl-l-ascorbic acid by site-saturation engineering of subsite-3 in cyclodextrin glycosyltransferase from Paenibacillus macerans.
Long Liu, Qiaoyan Xu, Ruizhi Han, Hyun-dong Shin, Rachel R Chen, Guocheng Du, Jian Chen

J Biotechnol· July 2013

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Developing Bacillus spp. as a cell factory for production of microbial enzymes and industrially important biochemicals in the context of systems and synthetic biology.
Long Liu, Yanfeng Liu, Hyun-Dong Shin, Rachel R Chen, Nam Sun Wang, Guocheng Du, Jian Chen

Appl Microbiol Biotechnol· July 2013

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Impact of expression of EMP enzymes on glucose metabolism in Zymomonas mobilis.
Rachel Ruizhen Chen, Manoj Agrawal, Zichao Mao

Appl Biochem Biotechnol· June 2013

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Fusion of an oligopeptide to the N terminus of an alkaline α-amylase from Alkalimonas amylolytica simultaneously improves the enzyme's catalytic efficiency, thermal stability, and resistance to oxidation.
Haiquan Yang, Xinyao Lu, Long Liu, Jianghua Li, Hyun-dong Shin, Rachel R Chen, Guocheng Du, Jian Chen

Appl Environ Microbiol· May 2013

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Carbohydrate-binding module-cyclodextrin glycosyltransferase fusion enables efficient synthesis of 2-O-d-glucopyranosyl-l-ascorbic acid with soluble starch as the glycosyl donor.
Ruizhi Han, Jianghua Li, Hyun-Dong Shin, Rachel R Chen, Guocheng Du, Jian Chen

Appl Environ Microbiol· May 2013

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Structure-based engineering of histidine residues in the catalytic domain of α-amylase from Bacillus subtilis for improved protein stability and catalytic efficiency under acidic conditions.
Haiquan Yang, Long Liu, Hyun-dong Shin, Rachel R Chen, Jianghua Li, Guocheng Du, Jian Chen

J Biotechnol· March 2013

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Systems engineering of tyrosine 195, tyrosine 260, and glutamine 265 in cyclodextrin glycosyltransferase from Paenibacillus macerans to enhance maltodextrin specificity for 2-O-(D)-glucopyranosyl-(L)-ascorbic acid synthesis.
Ruizhi Han, Long Liu, Hyun-Dong Shin, Rachel R Chen, Jianghua Li, Guocheng Du, Jian Chen

Appl Environ Microbiol· January 2013

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High-yield production of meso-2,3-butanediol from cellodextrin by engineered E. coli biocatalysts.
Hyun-Dong Shin, San-Hwal Yoon, Jianrong Wu, Charles Rutter, Seon-Won Kim, Rachel R Chen

Bioresour Technol· August 2012

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