Publications by authors named "Rachelle Gent"

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C11-hydroxy and C11-oxo C and C Steroids: Pre-Receptor Regulation and Interaction with Androgen and Progesterone Steroid Receptors.
Rachelle Gent, Desmaré Van Rooyen, Stephen L Atkin, Amanda C Swart

Int J Mol Sci· December 2023

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Ultra-performance convergence chromatography tandem mass spectrometry analysis of adrenal and gonadal steroid hormones in southern white rhinoceros(Ceratotherium simum simum) faeces and serum.
Rachelle Gent, Inge D Barbier, Stephen L Atkin, Annie E Newell-Fugate, Amanda C Swart

J Chromatogr B Analyt Technol Biomed Life Sci· January 2023

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11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro.
Rachelle Gent, Therina du Toit, Amanda C Swart

J Steroid Biochem Mol Biol· July 2019

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The 11β-hydroxysteroid dehydrogenase isoforms: pivotal catalytic activities yield potent C11-oxy C steroids with 11βHSD2 favouring 11-ketotestosterone, 11-ketoandrostenedione and 11-ketoprogesterone biosynthesis.
Rachelle Gent, Therina du Toit, Liezl M Bloem, Amanda C Swart

J Steroid Biochem Mol Biol· May 2019

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The in vitro metabolism of 11β-hydroxyprogesterone and 11-ketoprogesterone to 11-ketodihydrotestosterone in the backdoor pathway.
Desmaré van Rooyen, Rachelle Gent, Lise Barnard, Amanda C Swart

J Steroid Biochem Mol Biol· April 2018

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Adrenal C11-oxy C steroids contribute to the C11-oxy C steroid pool via the backdoor pathway in the biosynthesis and metabolism of 21-deoxycortisol and 21-deoxycortisone.
Lise Barnard, Rachelle Gent, Desmaré van Rooyen, Amanda C Swart

J Steroid Biochem Mol Biol· November 2017

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