Publications by authors named "Radhakrishnan Mahadevan"

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Establishing a quantitative link between crystal violet absorbance and biomass in biofilms.
Sheida Stephens, Radhakrishnan Mahadevan, D Grant Allen

MethodsX· December 2025

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Improving a photosynthetic bioprocess with a ubiquitous additive: Using clay powder in the cultivation of .
Sheida Stephens, Mona Abo-Hashesh, Radhakrishnan Mahadevan, D Grant Allen

Biotechnol Rep (Amst)· December 2025

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Modeling reveals a metabolic basis of competition among strains during tandem chloroform and dichloromethane metabolism.
Olivia Bulka, Elizabeth A Edwards, Radhakrishnan Mahadevan

mSystems· October 2025

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Model-Based Optimization of a qCRISPRi Circuit for Dynamic Control of Metabolic Pathways.
Sai Akhil Golla, Mona Abo-Hashesh, Dev Gupta, Yilan Liu, Radhakrishnan Mahadevan

ACS Synth Biol· October 2025

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Cell Geometry and Membrane Protein Crowding Constrain Growth Rate, Overflow Metabolism, Respiration, and Maintenance Energy.
Ross P Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, William R Harcombe, Radhakrishnan Mahadevan

bioRxiv· August 2025

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CPI-Pred: A deep learning framework for predicting functional parameters of compound-protein interactions.
Zhiqing Xu, Rana Ahmed Barghout, Jinghao Wu, Dhruv Garg, Yun S Song, Radhakrishnan Mahadevan

bioRxiv· January 2025

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Computation-guided transcription factor biosensor specificity engineering for adipic acid detection.
Chester Pham, Peter J Stogios, Alexei Savchenko, Radhakrishnan Mahadevan

Comput Struct Biotechnol J· December 2024

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Pangenomic insights into evolution and acquisition of functional genes for bioremediation.
Olivia Bulka, Radhakrishnan Mahadevan, Elizabeth A Edwards

Microb Genom· November 2024

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DyMMM-LEAPS: An ML-based framework for modulating evenness and stability in synthetic microbial communities.
Ruhi Choudhary, Radhakrishnan Mahadevan

Biophys J· September 2024

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Functional and structural characterization of an IclR family transcription factor for the development of dicarboxylic acid biosensors.
Chester Pham, Mohamed A Nasr, Tatiana Skarina, Rosa Di Leo, David H Kwan, Radhakrishnan Mahadevan

FEBS J· August 2024

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Ni(II)-binding affinity of CcNikZ-II and its homologs: the role of the HH-prong and variable loop revealed by structural and mutational studies.
Patrick Diep, Peter J Stogios, Elena Evdokimova, Alexei Savchenko, Radhakrishnan Mahadevan

FEBS J· July 2024

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Design and Characterization of a Generalist Biosensor for Indole Derivatives.
Chester Pham, Peter J Stogios, Alexei Savchenko, Radhakrishnan Mahadevan

ACS Synth Biol· July 2024

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FOCUS on NOD2: Advancing IBD Drug Discovery with a User-Informed Machine Learning Framework.
Ruhi Choudhary, Radhakrishnan Mahadevan

ACS Med Chem Lett· July 2024

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From cassette to : a key genomic neighborhood in a chloroform and dichloromethane-transforming microbial consortium.
Olivia Bulka, Katherine Picott, Radhakrishnan Mahadevan, Elizabeth A Edwards

Appl Environ Microbiol· June 2024

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Evaluating the feasibility of medium-chain oleochemical synthesis using microbial chain elongation.
Ethan Agena, Ian M Gois, Connor M Bowers, Radhakrishnan Mahadevan, Matthew J Scarborough

J Ind Microbiol Biotechnol· January 2024

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Advances in generative modeling methods and datasets to design novel enzymes for renewable chemicals and fuels.
Rana A Barghout, Zhiqing Xu, Siddharth Betala, Radhakrishnan Mahadevan

Curr Opin Biotechnol· December 2023

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A Multifunctional ? Tandem Chloroform and Dichloromethane Degradation in a Mixed Microbial Culture.
Olivia Bulka, Jennifer Webb, Sandra Dworatzek, Radhakrishnan Mahadevan, Elizabeth A Edwards

Environ Sci Technol· December 2023

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Quantifying metal-binding specificity of CcNikZ-II from Clostridium carboxidivorans in the presence of competing metal ions.
Patrick Diep, Brayden Kell, Alexander Yakunin, Andreas Hilfinger, Radhakrishnan Mahadevan

Anal Biochem· September 2023

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Engineering Escherichia coli to produce aromatic chemicals from ethylene glycol.
Smaranika Panda, Jie Fu J Zhou, Michelle Feigis, Emma Harrison, Xiaoqiang Ma, Radhakrishnan Mahadevan

Metab Eng· September 2023

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Genetic Engineering of Using CRISPR Systems To Mitigate Toxic Release in Biomining.
Jinjin Chen, Yilan Liu, Radhakrishnan Mahadevan

Environ Sci Technol· August 2023

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Engineered nickel bioaccumulation in by NikABCDE transporter and metallothionein overexpression.
Patrick Diep, Heping Leo Shen, Julian A Wiesner, Nadia Mykytczuk, Vladimiros Papangelakis, Radhakrishnan Mahadevan

Eng Life Sci· July 2023

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Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics.
Meenakshi Venkatesan, Michael Fruci, Lou Ann Verellen, Tatiana Skarina, Nathalie Mesa, Radhakrishnan Mahadevan

Nat Commun· July 2023

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A Universal Strategy to Promote Secretion of G+/G- Bacterial Extracellular Vesicles and Its Application in Host Innate Immune Responses.
Yilan Liu, Jinjin Chen, Kaushik Raj, Lauren Baerg, Nayanan Nathan, Radhakrishnan Mahadevan

ACS Synth Biol· January 2023

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Recent progress in microbial fuel cells using substrates from diverse sources.
Jayesh M Sonawane, Radhakrishnan Mahadevan, Ashok Pandey, Jesse Greener

Heliyon· December 2022

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Genome-Scale Metabolic Modeling Reveals Sequential Dysregulation of Glutathione Metabolism in Livers from Patients with Alcoholic Hepatitis.
Alexandra Manchel, Radhakrishnan Mahadevan, Ramon Bataller, Jan B Hoek, Rajanikanth Vadigepalli

Metabolites· November 2022

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