Publications by authors named "Radhakrishnan Suresh"

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Anticancer efficacy of 3-(4-isopropyl) benzylidene-8-ethoxy, 6-methyl, chroman-4-one (SBL-060), a novel, dual, estrogen receptor-Akt kinase inhibitor in acute myeloid leukemia cells.
Mesfer Al Shahrani, Prasanna Rajagopalan, Mohammad Abohassan, Mohammad Alshahrani, Yasser Alraey, Suresh Radhakrishnan

Oncol Res· June 2023

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Computational analysis and in vitro evaluation of TMF 104, for its antioxidant, antimicrobial, and anticancer efficacies.
Ahmed Saif, Mesfer Al Shahrani, Mohammed Alshehri, Mohammad Abohassan, Mohammed A Alshehri, Suresh Radhakrishnan

Biotechnol Appl Biochem· February 2023

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FNF-12, a novel benzylidene-chromanone derivative, attenuates inflammatory response in in vitro and in vivo asthma models mediated by M2-related Th2 cytokines via MAPK and NF-kB signaling.
Mohammad Abohassan, Mesfer Al Shahrani, Mohammad Y Alshahrani, Naseem Begum, Suresh Radhakrishnan

Pharmacol Rep· February 2022

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Neurological Disorders Seen During Second Wave of SARS-CoV-2 Pandemic from Two Tertiary Care Centers in Central and Southern Kerala.
Minu George, Neena Baby, Ameen Azad, Aswathy Rajan, Suresh Kumar Radhakrishnan

Ann Indian Acad Neurol· December 2021

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Structure activity evaluation and computational analysis identify potent, novel 3-benzylidene chroman-4-one analogs with anti-fungal, anti-oxidant, and anti-cancer activities.
Gaffar Sarwar Zaman, Hossam Kamli, Suresh Radhakrishnan, Irfan Ahmad, Hassan Otifi

Drug Dev Ind Pharm· September 2021

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Computational and in vitro characterization of ICY-5: A potential candidate promoting mitochondrial apoptosis via the c-MET and STAT3 pathways.
Mesfer Al Shahrani, Meenakshisundaram Balasubramaniam, Mohammad Y Alshahrani, Ahmed Saif, Ayed A Dera, Suresh Radhakrishnan

J Cell Physiol· January 2021

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Biallelic loss-of-function variants in TBC1D2B cause a neurodevelopmental disorder with seizures and gingival overgrowth.
Frederike L Harms, Padmini Parthasarathy, Dennis Zorndt, Malik Alawi, Sigrid Fuchs, Suresh K Radhakrishnan

Hum Mutat· September 2020

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Biological evaluation of 2-arylidene-4, 7-dimethyl indan-1-one (FXY-1): a novel Akt inhibitor with potent activity in lung cancer.
Prasanna Rajagopalan, Khalid A Alahmari, Ashraf A Elbessoumy, Meenakshisundaram Balasubramaniam, Radhakrishnan Suresh

Cancer Chemother Pharmacol· February 2016

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Efficacy of oncolytic mutants targeting pRb and p53 pathways is synergistically enhanced when combined with cytotoxic drugs in prostate cancer cells and tumor xenografts.
Suresh Radhakrishnan, Enrique Miranda, Maria Ekblad, Alan Holford, Maria Tome Pizarro

Hum Gene Ther· October 2010

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Retraction for Radhakrishnan et al., B7-DC cross-linking restores antigen uptake and augments antigen-presenting cell function by matured dendritic cells.
Suresh Radhakrishnan, Esteban Celis, Larry R Pease

Proc Natl Acad Sci U S A· May 2010

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Cross-linking the B7 family molecule B7-DC directly activates immune functions of dendritic cells.
Loc T. Nguyen, Suresh Radhakrishnan, Bogoljub Ciric, Koji Tamada, Tahiro Shin

J Exp Med· April 2010

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Retraction: Indirect recruitment of a CD40 signaling pathway in dendritic cells by B7-DC cross-linking antibody modulates T cell functions.
Suresh Radhakrishnan, Rosalyn Cabrera, Kristina M. Bruns, Virginia P. Van Keulen, Michael J. Hansen

PLoS One· March 2010

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Indirect recruitment of a CD40 signaling pathway in dendritic cells by B7-DC cross-linking antibody modulates T cell functions.
Suresh Radhakrishnan, Rosalyn Cabrera, Kristina M Bruns, Virginia P Van Keulen, Michael J Hansen

PLoS One· July 2009

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Asthma-related environmental fungus, Alternaria, activates dendritic cells and produces potent Th2 adjuvant activity.
Takao Kobayashi, Koji Iijima, Suresh Radhakrishnan, Vinay Mehta, Robert Vassallo

J Immunol· February 2009

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TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells.
Suresh Radhakrishnan, Laura N Arneson, Jadee L Upshaw, Charles L Howe, Sara J Felts

J Immunol· December 2008

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Reprogrammed FoxP3+ T regulatory cells become IL-17+ antigen-specific autoimmune effectors in vitro and in vivo.
Suresh Radhakrishnan, Rosalyn Cabrera, Erin L Schenk, Pilar Nava-Parada, Michael P Bell

J Immunol· September 2008

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T-bet expression by dendritic cells is required for the repolarization of allergic airway inflammation.
Karin L Heckman, Suresh Radhakrishnan, Tobias Peikert, Koji Iijima, Hugh C McGregor

Eur J Immunol· September 2008

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Fast-tracked CTL: rapid induction of potent anti-tumor killer T cells in situ.
Karin L Heckman, Erin L Schenk, Suresh Radhakrishnan, Kevin D Pavelko, Michael J Hansen

Eur J Immunol· July 2007

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Induction of a Th1 response from Th2-polarized T cells by activated dendritic cells: dependence on TCR:peptide-MHC interaction, ICAM-1, IL-12, and IFN-gamma.
Suresh Radhakrishnan, Karla R Wiehagen, Vesna Pulko, Virginia Van Keulen, William A Faubion

J Immunol· March 2007

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B7-DC/PD-L2 cross-linking induces NF-kappaB-dependent protection of dendritic cells from cell death.
Suresh Radhakrishnan, Loc T Nguyen, Bogoljub Ciric, Virginia P Van Keulen, Larry R Pease

J Immunol· February 2007

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An infectious cause for prostate cancer.
Suresh Radhakrishnan, Angela Lee, Tim Oliver, Frank Chinegwundoh

BJU Int· February 2007

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Induction of a gene expression program in dendritic cells with a cross-linking IgM antibody to the co-stimulatory molecule B7-DC.
Frank A Blocki, Suresh Radhakrishnan, Virginia P Van Keulen, Karin L Heckman, Bogoljub Ciric

FASEB J· November 2006

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Botox in urology.
Ali Thwaini, Iqbal Shergill, Suresh Radhakrishnan, Frank Chinegwundoh, Hadeel Thwaini

Int Urogynecol J Pelvic Floor Dysfunct· September 2006

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Nurse-led flexible cystoscopy: experience from one UK centre.
Suresh Radhakrishnan, Trevor J Dorkin, Prakash Johnson, Praveen Menezes, Damian Greene

BJU Int· August 2006

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STAT4- and STAT6-signaling molecules in a murine model of multiple sclerosis.
Moses Rodriguez, Laurie Zoecklein, Jeffrey D Gamez, Kevin D Pavelko, Louisa M Papke, Suresh Radhakrishnan

FASEB J· February 2006

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