Publications by authors named "Radu Minea"

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Potent Therapeutic Activity of NEO212 in Preclinical Models of Human and Canine Leukaemia and Lymphoma.
Thomas C Chen, Steve Swenson, Thu Zan Thein, Radu O Minea, Axel H Schönthal

Vet Comp Oncol· September 2025

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NEO212, temozolomide conjugated to NEO100, exerts superior therapeutic activity over temozolomide in preclinical chemoradiation models of glioblastoma.
Radu O Minea, Thu Zan Thein, Zhuoyue Yang, Mihaela Campan, Pamela M Ward

Neurooncol Adv· June 2024

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Activation of Epstein-Barr Virus' Lytic Cycle in Nasopharyngeal Carcinoma Cells by NEO212, a Conjugate of Perillyl Alcohol and Temozolomide.
Hannah Hartman-Houstman, Steve Swenson, Radu O Minea, Uttam K Sinha, Ming-Fu Chiang

Cancers (Basel)· February 2024

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Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate.
Mengting Ou, Hee-Yeon Cho, Jie Fu, Thu Zan Thein, Weijun Wang, Radu O Minea

Autophagy· December 2023

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Enhanced brain entry of checkpoint-inhibitory therapeutic antibodies facilitated by intraarterial NEO100 in mouse models of brain-localized malignancies.
Weijun Wang, Haiping He, Shan Zeng, Hee-Yeon Cho, Radu O Minea

J Neurosurg· September 2023

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NEO212, a Perillyl Alcohol-Temozolomide Conjugate, Triggers Macrophage Differentiation of Acute Myeloid Leukemia Cells and Blocks Their Tumorigenicity.
Thomas C Chen, Radu O Minea, Steve Swenson, Zhuoyue Yang, Thu Zan Thein

Cancers (Basel)· December 2022

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Potentially Curative Therapeutic Activity of NEO212, a Perillyl Alcohol-Temozolomide Conjugate, in Preclinical Cytarabine-Resistant Models of Acute Myeloid Leukemia.
Axel H Schönthal, Steve Swenson, Radu O Minea, Hye Na Kim, Heeyeon Cho

Cancers (Basel)· July 2021

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Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas.
Radu O Minea, Tuan Cao Duc, Stephen D Swenson, Hee-Yeon Cho, Mickey Huang

PLoS One· October 2020

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Cytotoxic impact of a perillyl alcohol-temozolomide conjugate, NEO212, on cutaneous T-cell lymphoma .
Catalina Silva-Hirschberg, Hannah Hartman, Samantha Stack, Steve Swenson, Radu O Minea

Ther Adv Med Oncol· December 2019

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A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice.
Steve Swenson, Radu O Minea, Cao Duc Tuan, Thu-Zan Thein, Thomas C Chen

Molecules· November 2018

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Rare Stochastic Expression of O6-Methylguanine- DNA Methyltransferase (MGMT) in MGMT-Negative Melanoma Cells Determines Immediate Emergence of Drug-Resistant Populations upon Treatment with Temozolomide In Vitro and In Vivo.
Thomas C Chen, Nymph Chan, Radu O Minea, Hannah Hartman, Florence M Hofman

Cancers (Basel)· September 2018

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Multimeric disintegrin protein polymer fusions that target tumor vasculature.
Siti M Janib, Joshua A Gustafson, Radu O Minea, Stephen D Swenson, Shuanglong Liu

Biomacromolecules· July 2014

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Development of a chimeric recombinant disintegrin as a cost-effective anti-cancer agent with promising translational potential.
Radu Minea, Corey Helchowski, Barbara Rubino, Kyle Brodmann, Stephen Swenson

Toxicon· March 2012

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Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities.
Radu O Minea, Corey M Helchowski, Samuel J Zidovetzki, Fritz K Costa, Stephen D Swenson

PLoS One· June 2010

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The use of pepsin in receptor internalization assays.
Corey M Helchowski, Radu O Minea, Stephen D Swenson, Francis S Markland

Biochem Biophys Res Commun· October 2009

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Development of a novel recombinant disintegrin, contortrostatin, as an effective anti-tumor and anti-angiogenic agent.
Radu Minea, Stephen Swenson, Fritz Costa, Thomas C Chen, Francis S Markland

Pathophysiol Haemost Thromb· July 2006

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Intravenous liposomal delivery of the snake venom disintegrin contortrostatin limits breast cancer progression.
Stephen Swenson, Fritz Costa, Radu Minea, Russell P Sherwin, William Ernst

Mol Cancer Ther· April 2004

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