Publications by authors named "Raffael Schaffrath"

Claim this Profile
E
Evolutionary conservation of ubiquitin-like protein urmylation as revealed by URM1 gene shuffle from archaea to yeast.
Katharina Zupfer, Lars Kaduhr, Larissa Bessler, Mark Helm, Raffael Schaffrath

Commun Biol· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Autophosphorylation of conserved yeast and human casein kinase 1 isozymes regulates Elongator-dependent tRNA modifications.
Maria Friederike Landrock, Rościsław Krutyhołowa, Pauline Böhnert, Jarosław Mazur, Małgorzata Honc, Raffael Schaffrath

Nucleic Acids Res· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Diphthamide synthesis is linked to the eEF2-client chaperone machinery.
Lars Kaduhr, Klaus Mayer, Raffael Schaffrath, Johannes Buchner, Ulrich Brinkmann

FEBS Lett· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
tRNA binding to Kti12 is crucial for wobble uridine modification by Elongator.
David Scherf, Alexander Hammermeister, Pauline Böhnert, Alicia Burkard, Mark Helm, Raffael Schaffrath

Nucleic Acids Res· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Diphthamide formation in Arabidopsis requires DPH1-interacting DPH2 for light and oxidative stress resistance.
Hongliang Zhang, Nadežda Janina, Koray Ütkür, Thirishika Manivannan, Lei Zhang, Raffael Schaffrath

Plant Physiol· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fluoropyrimidines trigger decay of hypomodified tRNA in yeast.
Katharina Görlitz, Larissa Bessler, Mark Helm, Raffael Schaffrath, Roland Klassen

Nucleic Acids Res· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cryo-EM structures of the human Elongator complex at work.
Nour-El-Hana Abbassi, Marcin Jaciuk, David Scherf, Pauline Böhnert, Alexander Rau, Raffael Schaffrath

Nat Commun· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional Integrity of Radical SAM Enzyme Dph1•Dph2 Requires Non-Canonical Cofactor Motifs with Tandem Cysteines.
Koray Ütkür, Klaus Mayer, Shihui Liu, Ulrich Brinkmann, Raffael Schaffrath

Biomolecules· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evolutionary Conservation in Protein-Protein Interactions and Structures of the Elongator Sub-Complex ELP456 from and Yeast.
Sang Eun Jun, Kiu-Hyung Cho, Raffael Schaffrath, Gyung-Tae Kim

Int J Mol Sci· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Diphthamide - a conserved modification of eEF2 with clinical relevance.
Raffael Schaffrath, Ulrich Brinkmann

Trends Mol Med· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Science around the world.
Pedro Antas, Abigail Cleveland, Paolo Contessotto, Raffael Schaffrath

Trends Mol Med· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Lipidome remodeling in response to nutrient replenishment requires the tRNA modifier Deg1/Pus3 in yeast.
Gabriel Soares Matos, Leonie Vogt, Rosangela Silva Santos, Aurélien Devillars, Marcos Yukio Yoshinaga, Raffael Schaffrath

Mol Microbiol· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications.
Mark Helm, Markus T Bohnsack, Thomas Carell, Alexander Dalpke, Karl-Dieter Entian, Raffael Schaffrath

ACS Chem Biol· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Gene Mutations Identify a Candidate SAM Pocket in Radical Enzyme Dph1•Dph2 for Diphthamide Synthesis on EF2.
Koray Ütkür, Sarina Schmidt, Klaus Mayer, Roland Klassen, Ulrich Brinkmann, Raffael Schaffrath

Biomolecules· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Y
Yeast gene (alias ) operates in the initiation step of diphthamide synthesis on elongation factor 2.
Meike Arend, Koray Ütkür, Harmen Hawer, Klaus Mayer, Namit Ranjan, Raffael Schaffrath

Microb Cell· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DPH1 and DPH2 variants that confer susceptibility to diphthamide deficiency syndrome in human cells and yeast models.
Koray Ütkür, Klaus Mayer, Maliha Khan, Thirishika Manivannan, Raffael Schaffrath

Dis Model Mech· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cryo-EM structure of the fully assembled Elongator complex.
Marcin Jaciuk, David Scherf, Karol Kaszuba, Monika Gaik, Alexander Rau, Raffael Schaffrath

Nucleic Acids Res· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation.
Keerthiraju E Ravichandran, Lars Kaduhr, Bozena Skupien-Rabian, Ekaterina Shvetsova, Mikołaj Sokołowski, Raffael Schaffrath

EMBO J· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel DPH5-related diphthamide-deficiency syndrome causing embryonic lethality or profound neurodevelopmental disorder.
Suma P Shankar, Kristin Grimsrud, Louise Lanoue, Alena Egense, Brandon Willis, Raffael Schaffrath

Genet Med· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
AtELP4 a subunit of the Elongator complex in , mediates cell proliferation and dorsoventral polarity during leaf morphogenesis.
Sang Eun Jun, Kiu-Hyung Cho, Muhammad Aamir Manzoor, Tae Young Hwang, Youn Soo Kim, Raffael Schaffrath

Front Plant Sci· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel DPH5-related diphthamide-deficiency syndrome causing embryonic lethality or profound neurodevelopmental disorder.
Suma P Shankar, Kristin Grimsrud, Louise Lanoue, Alena Egense, Brandon Willis, Raffael Schaffrath

Genet Med· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis.
Hongliang Zhang, Julia Quintana, Koray Ütkür, Lorenz Adrian, Harmen Hawer, Raffael Schaffrath

Nat Commun· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identifying Interaction Partners of Yeast Protein Disulfide Isomerases Using a Small Thiol-Reactive Cross-Linker: Implications for Secretory Pathway Proteostasis.
Benjamin J Freije, Wilson M Freije, To Uyen Do, Grace E Adkins, Alexander Bruch, Raffael Schaffrath

Chem Res Toxicol· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Urm1, not quite a ubiquitin-like modifier?
Lars Kaduhr, Cindy Brachmann, Keerthiraju Ethiraju Ravichandran, James D West, Sebastian Glatt, Raffael Schaffrath

Microb Cell· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Role of in Phenotypic Variation of Strains Lacking -Dependent Pseudouridylation.
Bahar Khonsari, Roland Klassen, Raffael Schaffrath

Int J Mol Sci· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis