Publications by authors named "Raif Geha"

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S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis.
Mrinmoy Das, Mohammed Alasharee, Brian Woods, Saikat Mukherjee, Shira Kim, Raif S Geha

Immunity· November 2025

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The Mechanisms of Immunoglobulin E Sensitizations in Atopic Dermatitis.
Saikat Mukherjee, Raif S Geha, Mrinmoy Das

Immunol Allergy Clin North Am· November 2025

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Basophils in atopic dermatitis: Immunologic roles and clinical implications.
Mrinmoy Das, Raif S Geha

Ann Allergy Asthma Immunol· November 2025

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Skin levels of toxic shock syndrome toxin-1 predict the severity of atopic dermatitis.
Brian Woods, Samuel H Kilgore, Matthew Nikiciuk, Brittany Ripley, Ellen M Upton, Raif S Geha

J Allergy Clin Immunol· August 2025

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Factors associated with and kinetics of anti-IFN-α autoantibodies in deficiency.
Chen Wang, David Evan Potts, Bijun Sun, Marta Toth, Boglarka Ujhazi, Raif S Geha

J Allergy Clin Immunol Glob· August 2025

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DOCK8 in T cells promotes Th17 and Treg cell functionality to restrain mucosal mast cells and limit susceptibility to oral anaphylaxis.
Erin Janssen, Mrinmoy Das, Jordan Butts, Mohammed Alasharee, Saikat Mukherjee, Raif S Geha

Immunity· July 2025

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Retraction of Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice.
Jianqiang Bao, Carlos J Perez, Jeesun Kim, Huan Zhang, Caitlin J Murphy, Raif S Geha

JCI Insight· June 2025

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Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature.
Marita Bosticardo, Kerry Dobbs, Ottavia M Delmonte, Andrew J Martins, Francesca Pala, Raif S Geha

Sci Immunol· January 2025

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IL-4 acts on skin-derived dendritic cells to promote the T2 response to cutaneous sensitization and the development of allergic skin inflammation.
Juan Manuel Leyva-Castillo, Mrinmoy Das, Maria Strakosha, Alex McGurk, Emilie Artru, Raif S Geha

J Allergy Clin Immunol· December 2024

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Reflections on a half century of mentoring.
Raif S Geha

J Allergy Clin Immunol· October 2024

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Germline mutations in a G protein identify signaling cross-talk in T cells.
Hyoungjun Ham, Huie Jing, Ian T Lamborn, Megan M Kober, Alexey Koval, Raif S Geha

Science· September 2024

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Basophils Play a Protective Role in the Recovery of Skin Barrier Function from Mechanical Injury in Mice.
Maria Strakosha, Daniela Vega-Mendoza, Jennifer Kane, Ashish Jain, Liang Sun, Raif S Geha

J Invest Dermatol· August 2024

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Regulatory T-cell dysfunction and cutaneous exposure to Staphylococcus aureus underlie eczema in DOCK8 deficiency.
Hazel Wilkie, Mrinmoy Das, Tyler Pelovitz, Wayne Bainter, Brian Woods, Raif S Geha

J Allergy Clin Immunol· July 2024

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Basophils are important for development of allergic skin inflammation.
Juan-Manuel Leyva-Castillo, Daniela Vega-Mendoza, Maria Strakosha, Liwen Deng, Samantha Choi, Raif S Geha

J Allergy Clin Immunol· May 2024

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Phosphodiesterase 4 Inhibitors, Basophils, and Atopic Dermatitis.
Mrinmoy Das, Saikat Mukherjee, Raif S Geha

J Invest Dermatol· May 2024

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Clinical, immunological features, treatments, and outcomes of autoimmune hemolytic anemia in patients with RAG deficiency.
Chen Wang, Bijun Sun, Kevin Wu, Jocelyn R Farmer, Boglarka Ujhazi, Raif S Geha

Blood Adv· February 2024

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IL-4 receptor alpha blockade dampens allergic inflammation and upregulates IL-17A expression to promote Saureus clearance in antigen sensitized mouse skin.
Juan-Manuel Leyva-Castillo, Alex McGurk, Maria Strakosha, Daniela Vega-Mendoza, Sophia E M Smith, Raif S Geha

J Allergy Clin Immunol· October 2023

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Ant Venom-Based Ceramide Therapy Is Effective Against Atopic Dermatitis In Vivo.
Juan Manuel Leyva-Castillo, Christina Huang, Paola Baker, John Bacsa, Raif S Geha

J Drugs Dermatol· October 2023

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Multi-modal skin atlas identifies a multicellular immune-stromal community associated with altered cornification and specific T cell expansion in atopic dermatitis.
Evgenij Fiskin, Gökcen Eraslan, Maria B Alora-Palli, Juan Manuel Leyva-Castillo, Sean Kim, Raif Geha

bioRxiv· October 2023

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DOCK8 is essential for neutrophil mediated clearance of cutaneous S. aureus infection.
Hazel Wilkie, Maheshwor Timilshina, Siti Rahmayanti, Mrinmoy Das, Tyler Pelovitz, Raif S Geha

Clin Immunol· September 2023

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The IL-4Rα Q576R polymorphism is associated with increased severity of atopic dermatitis and exaggerates allergic skin inflammation in mice.
Barbara Yang, Hazel Wilkie, Mrinmoy Das, Maheshwor Timilshina, Wayne Bainter, Raif S Geha

J Allergy Clin Immunol· May 2023

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NFKB2 haploinsufficiency identified via screening for IFN-α2 autoantibodies in children and adolescents hospitalized with SARS-CoV-2-related complications.
Aaron Bodansky, Sara E Vazquez, Janet Chou, Tanya Novak, Amer Al-Musa, Raif S Geha

J Allergy Clin Immunol· April 2023

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A homozygous truncating mutation of FGL2 is associated with immune dysregulation.
Erin Janssen, Mohammad F Alosaimi, Anas M Alazami, Abdullah Alsuliman, Ayodele Alaiya, Raif S Geha

J Allergy Clin Immunol· February 2023

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The Middle East and North Africa Diagnosis and Management Guidelines for Inborn Errors of Immunity.
Safa Baris, Hassan Abolhassani, Michel J Massaad, Maryam Al-Nesf, Zahra Chavoshzadeh, Gehad ElGhazali, Raif S Geha

J Allergy Clin Immunol Pract· January 2023

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The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2-associated multisystem inflammatory syndrome in children.
Mehdi Benamar, Qian Chen, Janet Chou, Amélie M Julé, Rafik Boudra, Raif S Geha

J Clin Invest· January 2023

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