Publications by authors named "Rainer Nikolay"

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Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes.
Abin Biswas, Omar Muñoz, Kyoohyun Kim, Carsten Hoege, Benjamin M Lorton, Rainer Nikolay

Nat Commun· August 2025

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The proline-rich antimicrobial peptide Api137 disrupts large ribosomal subunit assembly and induces misfolding.
Simon Malte Lauer, Jakob Gasse, Andor Krizsan, Maren Reepmeyer, Thiemo Sprink, Rainer Nikolay

Nat Commun· January 2025

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Critical steps in the assembly process of the bacterial 50S ribosomal subunit.
Amal Seffouh, Rainer Nikolay, Joaquin Ortega

Nucleic Acids Res· May 2024

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Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88.
Simon M Lauer, Maren Reepmeyer, Ole Berendes, Dorota Klepacki, Jakob Gasse, Rainer Nikolay

Nat Commun· May 2024

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Decoding a ribosome uncertainty.
Olivier Duss, Rainer Nikolay, Matthew L Kraushar

Trends Genet· September 2023

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Cryo-EM captures early ribosome assembly in action.
Bo Qin, Simon M Lauer, Annika Balke, Carlos H Vieira-Vieira, Jörg Bürger, Rainer Nikolay

Nat Commun· February 2023

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Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Rainer Nikolay, Tarek Hilal, Sabine Schmidt, Bo Qin, David Schwefel

Mol Cell· March 2021

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Multifaceted Stoichiometry Control of Bacterial Operons Revealed by Deep Proteome Quantification.
Jing Zhao, Hong Zhang, Bo Qin, Rainer Nikolay, Qing-Yu He

Front Genet· May 2019

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Translatomics: The Global View of Translation.
Jing Zhao, Bo Qin, Rainer Nikolay, Christian M T Spahn, Gong Zhang

Int J Mol Sci· January 2019

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Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Rainer Nikolay, Tarek Hilal, Bo Qin, Thorsten Mielke, Jörg Bürger

Mol Cell· June 2018

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Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation.
Stefanie Ginster, Maureen Bardet, Adeline Unterreiner, Claire Malinverni, Florian Renner, Rainer Nikolay

PLoS One· August 2017

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Ribosome Assembly as Antimicrobial Target.
Rainer Nikolay, Sabine Schmidt, Renate Schlömer, Elke Deuerling, Knud H Nierhaus

Antibiotics (Basel)· May 2016

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Fluorescence-based monitoring of ribosome assembly landscapes.
Rainer Nikolay, Renate Schloemer, Silke Mueller, Elke Deuerling

BMC Mol Biol· February 2015

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Validation of a fluorescence-based screening concept to identify ribosome assembly defects in Escherichia coli.
Rainer Nikolay, Renate Schloemer, Sabine Schmidt, Silke Mueller, Anja Heubach

Nucleic Acids Res· July 2014

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Structural determinants of MALT1 protease activity.
Christian Wiesmann, Lukas Leder, Jutta Blank, Anna Bernardi, Samu Melkko, Rainer Nikolay

J Mol Biol· May 2012

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CHIP participates in protein triage decisions by preferentially ubiquitinating Hsp70-bound substrates.
Marta Stankiewicz, Rainer Nikolay, Vladimir Rybin, Matthias P Mayer

FEBS J· August 2010

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Insights into the conformational dynamics of the E3 ubiquitin ligase CHIP in complex with chaperones and E2 enzymes.
Christian Graf, Marta Stankiewicz, Rainer Nikolay, Matthias P Mayer

Biochemistry· March 2010

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A conserved cysteine motif essential for ceramide kinase function.
Emilie Lidome, Christine Graf, Markus Jaritz, Andrea Schanzer, Philipp Rovina, Rainer Nikolay

Biochimie· October 2008

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The Drosophila mitotic inhibitor Frühstart specifically binds to the hydrophobic patch of cyclins.
Pawel Gawliński, Rainer Nikolay, Catherine Goursot, Steffen Lawo, Bhagirath Chaurasia

EMBO Rep· May 2007

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A conserved motif is prerequisite for the interaction of NAC with ribosomal protein L23 and nascent chains.
Renee D Wegrzyn, Diana Hofmann, Frieder Merz, Rainer Nikolay, Thomas Rauch

J Biol Chem· February 2006

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Dimerization of the human E3 ligase CHIP via a coiled-coil domain is essential for its activity.
Rainer Nikolay, Thomas Wiederkehr, Wolfgang Rist, Günter Kramer, Matthias P Mayer

J Biol Chem· January 2004

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Aha, another regulator for hsp90 chaperones.
Matthias P Mayer, Rainer Nikolay, Bernd Bukau

Mol Cell· December 2002

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