Publications by authors named "Rajeev Samant"

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Ribosome Biogenesis Underpins Tumor Progression: A Comprehensive Signature for Survival and Immunotherapy Response Prediction.
Amr R Elhamamsy, Salma M Aly, Rajeev S Samant, Lalita A Shevde

Cancers (Basel)· August 2025

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Nucleolar proteomics identifies S100A16 as a key nucleolar protein driving breast cancer metastasis.
Brandon J Metge, Mohamed H Elbahoty, Amr R Elhamamsy, Anne E Popple, Bhavya Papineni, Rajeev S Samant

Cell Death Dis· August 2025

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Hypoxic stress incites HIF1α-driven ribosome biogenesis that can be exploited by targeting RNA Polymerase I.
Amr Elhamamsy, Brandon J Metge, Courtney A Swain, Mohamed H Elbahoty, Dominique C Hinshaw, Rajeev S Samant

Nat Commun· August 2025

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Ribosomal RNA Biosynthesis Functionally Programs Tumor-Associated Macrophages to Support Breast Cancer Progression.
Brandon J Metge, Li'an Williams, Courtney A Swain, Dominique C Hinshaw, Amr R Elhamamsy, Rajeev S Samant

Cancer Res· April 2025

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Multiple myeloma: clinical characteristics, current therapies and emerging innovative treatments targeting ribosome biogenesis dynamics.
Mohamed H Elbahoty, Bhavyasree Papineni, Rajeev S Samant

Clin Exp Metastasis· December 2024

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Targeting EMT using low-dose Teniposide by downregulating ZEB2-driven activation of RNA polymerase I in breast cancer.
Brandon J Metge, Heba Allah M Alsheikh, Sarah C Kammerud, Dongquan Chen, Devika Das, Rajeev S Samant

Cell Death Dis· May 2024

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Retraction: Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer.
Erhong Meng, Lalita A Shevde, Rajeev S Samant

Oncotarget· July 2023

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Ribosome biosynthesis and Hedgehog activity are cooperative actionable signaling mechanisms in breast cancer following radiotherapy.
Brandon J Metge, Heba A Alsheikh, Dongquan Chen, Amr R Elhamamsy, Dominique C Hinshaw, Rajeev S Samant

NPJ Precis Oncol· June 2023

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Hedgehog Signaling Regulates Treg to Th17 Conversion Through Metabolic Rewiring in Breast Cancer.
Dominique C Hinshaw, Gloria A Benavides, Brandon J Metge, Courtney A Swain, Sarah C Kammerud, Rajeev S Samant

Cancer Immunol Res· May 2023

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Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8 T cells in a mouse model of mammary carcinoma.
Dominique C Hinshaw, Courtney A Swain, Dongquan Chen, Ann Hanna, Patrick A Molina, Rajeev S Samant

Lab Invest· November 2022

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Ribosome Biogenesis: A Central Player in Cancer Metastasis and Therapeutic Resistance.
Amr R Elhamamsy, Brandon J Metge, Heba A Alsheikh, Lalita A Shevde, Rajeev S Samant

Cancer Res· July 2022

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Quantitative Longitudinal Imaging Reveals that Inhibiting Hedgehog Activity Alleviates the Hypoxic Tumor Landscape.
Tshering D Lama-Sherpa, Shamik Das, Dominique C Hinshaw, Sarah C Kammerud, Patrick N Song, Rajeev S Samant

Mol Cancer Res· January 2022

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Novel role of the dietary flavonoid fisetin in suppressing rRNA biogenesis.
Sarah C Kammerud, Brandon J Metge, Amr R Elhamamsy, Shannon E Weeks, Heba A Alsheikh, Rajeev S Samant

Lab Invest· November 2021

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Hedgehog Signaling Regulates Metabolism and Polarization of Mammary Tumor-Associated Macrophages.
Dominique C Hinshaw, Ann Hanna, Tshering Lama-Sherpa, Brandon Metge, Sarah C Kammerud, Rajeev S Samant

Cancer Res· November 2021

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Normalizing glucose levels reconfigures the mammary tumor immune and metabolic microenvironment and decreases metastatic seeding.
Heba Allah M Alsheikh, Brandon J Metge, Chae-Myeong Ha, Dominique C Hinshaw, Mateus S V Mota, Rajeev S Samant

Cancer Lett· October 2021

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Isolation of Nucleoli for Characterization of Nucleolar Contents to Uncover Clues to Metastatic Progression.
Shannon E Weeks, Rajeev S Samant

Methods Mol Biol· June 2021

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Disruption of STAT5A and NMI signaling axis leads to ISG20-driven metastatic mammary tumors.
Heba Allah M Alsheikh, Brandon J Metge, Hawley C Pruitt, Sarah C Kammerud, Dongquan Chen, Rajeev S Samant

Oncogenesis· June 2021

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Merlin deficiency alters the redox management program in breast cancer.
Mateus Mota, Brandon J Metge, Dominique C Hinshaw, Heba A Alsheikh, Dongquan Chen, Rajeev S Samant

Mol Oncol· April 2021

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Inhibiting β-catenin disables nucleolar functions in triple-negative breast cancer.
Shannon E Weeks, Sarah C Kammerud, Brandon J Metge, Heba A AlSheikh, David A Schneider, Rajeev S Samant

Cell Death Dis· March 2021

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Hypoxia re-programs 2'-O-Me modifications on ribosomal RNA.
Brandon J Metge, Sarah C Kammerud, Hawley C Pruitt, Lalita A Shevde, Rajeev S Samant

iScience· January 2021

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Hedgehog signaling enables repair of ribosomal DNA double-strand breaks.
Tshering D Lama-Sherpa, Victor T G Lin, Brandon J Metge, Shannon E Weeks, Dongquan Chen, Rajeev S Samant

Nucleic Acids Res· October 2020

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The nucleolus: a central response hub for the stressors that drive cancer progression.
Shannon E Weeks, Brandon J Metge, Rajeev S Samant

Cell Mol Life Sci· November 2019

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O-GlcNAcylation of GLI transcription factors in hyperglycemic conditions augments Hedgehog activity.
Shamik Das, Sarah K Bailey, Brandon J Metge, Ann Hanna, Dominique C Hinshaw, Rajeev S Samant

Lab Invest· February 2019

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Phage Ligands for Identification of Mesenchymal-Like Breast Cancer Cells and Cancer-Associated Fibroblasts.
Kelvin M Jones, Balasubramanyam Karanam, Jacqueline Jones-Triche, Maninder Sandey, Henry J Henderson, Rajeev S Samant

Front Oncol· December 2018

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Inhibition of Hedgehog signaling reprograms the dysfunctional immune microenvironment in breast cancer.
Ann Hanna, Brandon J Metge, Sarah K Bailey, Dongquan Chen, Darshan S Chandrashekar, Rajeev S Samant

Oncoimmunology· December 2018

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