Publications by authors named "Rajesh Abraham Jacob"

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Distinct circulating autoantibodies are associated with COVID-19 hospitalization and SARS-CoV-2 neutralization activity.
Rajesh Abraham Jacob, Hannah O Ajoge, Michael R D'Agostino, Altynay Shigayeva, Arinjay Banerjee

Npj Viruses· September 2025

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ASK1 inhibitors are potential pan-antiviral drugs, which dampen replication of diverse viruses including SARS-CoV2.
Wael L Demian, Rajesh Abraham Jacob, Olga Cormier, Aisha Nazli, Matthew Melki

Antiviral Res· December 2023

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Sensitivity to Neutralizing Antibodies and Resistance to Type I Interferons in SARS-CoV-2 R.1 Lineage Variants, Canada.
Rajesh Abraham Jacob, Ali Zhang, Hannah O Ajoge, Michael R D'Agostino, Kuganya Nirmalarajah

Emerg Infect Dis· July 2023

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Altered microRNA Transcriptome in Cultured Human Airway Cells upon Infection with SARS-CoV-2.
Idrissa Diallo, Rajesh Abraham Jacob, Elodie Vion, Robert A Kozak, Karen Mossman

Viruses· February 2023

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The HIV-1 accessory protein Nef increases surface expression of the checkpoint receptor Tim-3 in infected CD4 T cells.
Rajesh Abraham Jacob, Cassandra R Edgar, Jérémie Prévost, Steven M Trothen, Antony Lurie

J Biol Chem· September 2021

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Efferocytic Defects in Early Atherosclerosis Are Driven by GATA2 Overexpression in Macrophages.
Charles Yin, Angela M Vrieze, Mara Rosoga, James Akingbasote, Emily N Pawlak, Rajesh Abraham Jacob

Front Immunol· June 2021

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Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses.
Arinjay Banerjee, Nader El-Sayes, Patrick Budylowski, Rajesh Abraham Jacob, Daniel Richard

iScience· May 2021

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HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4 T Cells.
Jérémie Prévost, Cassandra R Edgar, Jonathan Richard, Steven M Trothen, Rajesh Abraham Jacob

J Virol· March 2020

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PACS-1 and adaptor protein-1 mediate ACTH trafficking to the regulated secretory pathway.
Brennan S Dirk, Christopher End, Emily N Pawlak, Logan R Van Nynatten, Rajesh Abraham Jacob

Biochem Biophys Res Commun· December 2018

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Identification of Novel Subcellular Localization and Trafficking of HIV-1 Nef Variants from Reference Strains G (F1.93.HH8793) and H (BE.93.VI997).
Logan R Van Nynatten, Aaron L Johnson, Brennan S Dirk, Emily N Pawlak, Rajesh Abraham Jacob

Viruses· September 2018

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Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11.
Thandeka Moyo, June Ereño-Orbea, Rajesh Abraham Jacob, Clara E Pavillet, Samuel Mundia Kariuki

J Virol· July 2018

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The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4 T cells.
Emily N Pawlak, Brennan S Dirk, Rajesh Abraham Jacob, Aaron L Johnson, Jimmy D Dikeakos

Retrovirology· January 2018

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The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4 T cell apoptosis.
Rajesh Abraham Jacob, Aaron L Johnson, Emily N Pawlak, Brennan S Dirk, Logan R Van Nynatten

Virology· September 2017

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Viral bimolecular fluorescence complementation: a novel tool to study intracellular vesicular trafficking pathways.
Brennan S Dirk, Rajesh Abraham Jacob, Aaron L Johnson, Emily N Pawlak, P Craig Cavanagh

PLoS One· April 2016

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Anti-V3/Glycan and Anti-MPER Neutralizing Antibodies, but Not Anti-V2/Glycan Site Antibodies, Are Strongly Associated with Greater Anti-HIV-1 Neutralization Breadth and Potency.
Rajesh Abraham Jacob, Thandeka Moyo, Michael Schomaker, Fatima Abrahams, Berta Grau Pujol

J Virol· May 2015

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Refined identification of neutralization-resistant HIV-1 CRF02_AG viruses.
Rajesh Abraham Jacob, Fatima Abrahams, Marcel Tongo, Michael Schomaker, Paul Roux

J Virol· July 2012

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HIV-1 Tat-specific IgG antibodies in high-responders target a B-cell epitope in the cysteine-rich domain and block extracellular Tat efficiently.
Venkatesh Prasanna Kashi, Rajesh Abraham Jacob, Siddhartha Paul, Kaustuv Nayak, Bhuthiah Satish

Vaccine· November 2009

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