Publications by authors named "Rajesh Ghai"

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Structural basis for the inhibition of βFXIIa by garadacimab.
Ieva Drulyte, Rajesh Ghai, Saw Yen Ow, Eugene A Kapp, Adam J Quek

Structure· October 2024

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Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Michael D Healy, Kerrie E McNally, Rebeka Butkovič, Molly Chilton, Kohji Kato, Rajesh Ghai

Cell· May 2023

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Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins.
Michael D Healy, Joanna Sacharz, Kerrie E McNally, Calum McConville, Vikas A Tillu, Rajesh Ghai

Structure· December 2022

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De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Kai-En Chen, Qian Guo, Timothy A Hill, Yi Cui, Amy K Kendall, Rajesh Ghai

Sci Adv· December 2021

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Structural insights into the architecture and membrane interactions of the conserved COMMD proteins.
Michael D Healy, Manuela K Hospenthal, Ryan J Hall, Mintu Chandra, Molly Chilton, Rajesh Ghai

Elife· August 2018

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Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.
Kerrie E McNally, Rebecca Faulkner, Florian Steinberg, Matthew Gallon, Rajesh Ghai

Nat Cell Biol· October 2017

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ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P ) and regulate its level at the plasma membrane.
Rajesh Ghai, Ximing Du, Huan Wang, Jiangqing Dong, Charles Ferguson

Nat Commun· October 2017

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A role for novel lipid interactions in the dynamic recruitment of SNX27 to the T-cell immune synapse.
María Tello-Lafoz, Rajesh Ghai, Brett Collins, Isabel Mérida

Bioarchitecture· May 2016

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Phosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells.
Rajesh Ghai, Maria Tello-Lafoz, Suzanne J Norwood, Zhe Yang, Thomas Clairfeuille

J Cell Sci· February 2015

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The recognition of membrane-bound PtdIns3P by PX domains.
ZhiGuang Jia, Rajesh Ghai, Brett M Collins, Alan E Mark

Proteins· October 2014

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Structural basis for different phosphoinositide specificities of the PX domains of sorting nexins regulating G-protein signaling.
Caroline Mas, Suzanne J Norwood, Andrea Bugarcic, Genevieve Kinna, Natalya Leneva, Rajesh Ghai

J Biol Chem· October 2014

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A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
Matthew Gallon, Thomas Clairfeuille, Florian Steinberg, Caroline Mas, Rajesh Ghai

Proc Natl Acad Sci U S A· September 2014

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Measuring interactions of FERM domain-containing sorting Nexin proteins with endosomal lipids and cargo molecules.
Rajesh Ghai, Mehdi Mobli, Brett M Collins

Methods Enzymol· July 2014

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Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Rajesh Ghai, Andrea Bugarcic, Huadong Liu, Suzanne J Norwood, Sune Skeldal

Proc Natl Acad Sci U S A· February 2013

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Applications of isothermal titration calorimetry in pure and applied research--survey of the literature from 2010.
Rajesh Ghai, Robert J Falconer, Brett M Collins

J Mol Recognit· January 2012

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VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins.
James D Swarbrick, Daniel J Shaw, Sandeep Chhabra, Rajesh Ghai, Eugene Valkov

PLoS One· September 2011

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PX-FERM proteins: A link between endosomal trafficking and signaling?
Rajesh Ghai, Brett M Collins

Small GTPases· September 2011

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Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases.
Rajesh Ghai, Mehdi Mobli, Suzanne J Norwood, Andrea Bugarcic, Rohan D Teasdale

Proc Natl Acad Sci U S A· May 2011

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