Publications by authors named "Rajesh Krishnan"

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Desymmetrization of -Anhydride Enabled Enantioselective Synthesis of (-)-7-(Bromomethylene)-3-amidobicyclo[2.2.1]heptane-2-carboxamide, a Scaffold for Divergent Drug Discovery Synthesis.
Jianqing Li, Subramaniam Krishnananthan, Daniel Smith, Chetan Padmakar Darne, Ning Li, Rajesh Krishnan

J Org Chem· December 2025

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Siglec-F neutrophils promote the resolution of acute lung injury through ALOX15 induction.
Luciana P Tavares, Thayse R Brüggemann, R Elaine Cagnina, Robert Nshimiyimana, Ana B Villaseñor-Altamirano, Rajesh K Krishnan

Sci Immunol· December 2025

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SARS-CoV-2 spike antibody and T cell response in MS patients on high efficacy therapies post vaccine.
Shrishti Saxena, Alena Zhirova, Rajesh Krishnan, Brian Healy, Eunnindy Sanon, Niveditha Gopalakrishnan

J Neuroimmunol· October 2025

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Type I interferon limits central nervous system autoimmunity by modulating the microRNA-21-FOXO1 axis in pathogenic T helper 17 cells.
Johnna Francis Varghese, Mai Fujiwara, Amrendra K Ajay, Lucien P Garo, Alkeiver Cannon, Rajesh Krishnan

Sci Transl Med· September 2025

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Nasal anti-CD3 monoclonal antibody ameliorates traumatic brain injury, enhances microglial phagocytosis and reduces neuroinflammation via IL-10-dependent T-microglia crosstalk.
Saef Izzy, Taha Yahya, Omar Albastaki, Hadi Abou-El-Hassan, Michael Aronchik, Rajesh Krishnan

Nat Neurosci· March 2025

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Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy.
Wesley Brandao, Nimansha Jain, Zhuoran Yin, Kilian L Kleemann, Madison Carpenter, Rajesh Krishnan

Sci Transl Med· January 2025

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Comparison of a SARS-CoV-2 mRNA booster immunization containing additional antigens to a spike-based mRNA vaccine against Omicron BA.5 infection in hACE2 mice.
Jacklyn R Hurst, Maedeh Naghibosadat, Patrick Budowski, Jun Liu, Philip Samaan, Rajesh Krishnan

PLoS One· December 2024

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Transcription factor TCF1 binds to RORγt and orchestrates a regulatory network that determines homeostatic Th17 cell state.
Davide Mangani, Ayshwarya Subramanian, Linglin Huang, Hanning Cheng, S Harsha Krovi, Rajesh K Krishnan

Immunity· November 2024

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Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease.
Neta Rosenzweig, Kilian L Kleemann, Thomas Rust, Madison Carpenter, Madeline Grucci, Rajesh K Krishnan

Nat Med· October 2024

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BACH2 regulates diversification of regulatory and proinflammatory chromatin states in T17 cells.
Pratiksha I Thakore, Alexandra Schnell, Linglin Huang, Maryann Zhao, Yu Hou, Rajesh Kumar Krishnan

Nat Immunol· August 2024

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Pan-cancer mapping of single CD8 T cell profiles reveals a TCF1:CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity.
Katherine Tooley, Livnat Jerby, Giulia Escobar, S Harsha Krovi, Davide Mangani, Rajesh K Krishnan

Cell Rep Med· July 2024

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Bacteroidota inhibit microglia clearance of amyloid-beta and promote plaque deposition in Alzheimer's disease mouse models.
Caroline Wasén, Leah C Beauchamp, Julia Vincentini, Shuqi Li, Danielle S LeServe, Rajesh K Krishnan

Nat Commun· May 2024

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Human regulatory memory B cells defined by expression of TIM-1 and TIGIT are dysfunctional in multiple sclerosis.
Johnna F Varghese, Belinda J Kaskow, Felipe von Glehn, Junning Case, Zhenhua Li, Rajesh Krishnan

Front Immunol· May 2024

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APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints.
Zhuoran Yin, Neta Rosenzweig, Kilian L Kleemann, Xiaoming Zhang, Wesley Brandão, Rajesh K Krishnan

Nat Immunol· November 2023

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Mapping Processes in the Emergency Department Using the Functional Resonance Analysis Method.
Nathan Anderson, Rajesh G Krishnan, Maneesh Kumar, Tim Ayres, David Slater

Ann Emerg Med· September 2023

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Tumor immunogenicity dictates reliance on TCF1 in CD8 T cells for response to immunotherapy.
Giulia Escobar, Katherine Tooley, Joan Pagès Oliveras, Linglin Huang, Hanning Cheng, Rajesh K Krishnan

Cancer Cell· September 2023

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Vγ1 and Vγ4 gamma-delta T cells play opposing roles in the immunopathology of traumatic brain injury in males.
Hadi Abou-El-Hassan, Rafael M Rezende, Saef Izzy, Galina Gabriely, Taha Yahya, Rajesh Krishnan

Nat Commun· July 2023

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Preserved T cell but attenuated antibody response in MS patients on fingolimod and ocrelizumab following 2nd and 3rd SARS-CoV-2 mRNA vaccine.
Sarah Conway, Shrishti Saxena, Clare Baecher-Allan, Rajesh Krishnan, Maria Houtchens

Mult Scler J Exp Transl Clin· April 2023

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microRNA-92a promotes CNS autoimmunity by modulating the regulatory and inflammatory T cell balance.
Mai Fujiwara, Radhika Raheja, Lucien P Garo, Amrendra K Ajay, Ryoko Kadowaki-Saga, Rajesh Krishnan

J Clin Invest· May 2022

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Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells.
Galina Gabriely, Duanduan Ma, Shafiuddin Siddiqui, Linqing Sun, Nathaniel P Skillin, Rajesh Krishnan

iScience· November 2021

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When is biopsy-proven TIN not simply TIN? Questions.
Nicholas Ware, Neil J Sebire, W K Chong, Rajesh Krishnan, Stephen D Marks

Pediatr Nephrol· June 2017

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When is biopsy-proven TIN not simply TIN? Answers.
Nicholas Ware, Neil J Sebire, W K Chong, Rajesh Krishnan, Stephen D Marks

Pediatr Nephrol· June 2017

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Subdiaphragmatic Renal Ectopia: Case Report and Review of the Literature.
Eleftherios Zolotas, Rajesh G Krishnan

Case Rep Nephrol· September 2016

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Positive trends in paediatric renal biopsy service provision in the UK: a national survey and re-audit of paediatric renal biopsy practice.
Asheeta Gupta, Joanna Campion-Smith, Wesley Hayes, Jane E Deal, Rodney D Gilbert, Rajesh G Krishnan

Pediatr Nephrol· April 2016

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Hydrophilic polyurethane matrix promotes chondrogenesis of mesenchymal stem cells.
Sandeep M Nalluri, G Rajesh Krishnan, Calvin Cheah, Ayesha Arzumand, Yuan Yuan

Mater Sci Eng C Mater Biol Appl· September 2015

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