Publications by authors named "Rajesh Mani"

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Spatial transcriptomic analysis of HIV and tuberculosis coinfection in a humanized mouse model reveals unique transcription patterns, immune responses and early morphological alterations.
Sitaramaraju Adduri, Jose Alejandro Bohorquez, Rajesh Mani, Omoyeni Adejare, Diego Rincon

bioRxiv· September 2025

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Novel Protein Adjuvant Activating Innate IFN-γ and IL-18 Expression and Inducing Rejection of Implanted Colorectal Cancer Following Immunotherapy Using This Adjuvant in Mice.
Rajesh Mani, B Mark Evers, Yasuhiro Suzuki

Med Res Arch· June 2025

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Re-inventing traditional aluminum-based adjuvants: Insight into a century of advancements.
Himanshu Gogoi, Rajesh Mani, Rakesh Bhatnagar

Int Rev Immunol· April 2025

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Deficiencies of Inducible Costimulator (ICOS) During Chronic Infection with Upregulate the CD28-Dependent Cytotoxicity of CD8 T Cells and Their Effector Function Against Tissue Cysts of the Parasite.
Rajesh Mani, Kanal E Balu, Yasuhiro Suzuki

Cells· December 2024

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The Absence of CXCL10 Activity Does Not Affect the Capability of CD8 T Cells to Migrate and Eliminate the Tissue Cysts of from the Brains of Chronically Infected Mice.
Rajesh Mani, Yasuhiro Suzuki

Microorganisms· October 2024

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Cord blood platelet rich plasma (PRP) as a potential alternative to autologous PRP for allogenic preparation and regenerative applications.
Rajesh Mani, Purandhi Roopmani, Jayakumar Rajendran, Sradhanjali Maharana, Jyotsnendu Giri

Int J Biol Macromol· March 2024

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A Novel Protozoa Parasite-Derived Protein Adjuvant Is Effective in Immunization with Cancer Cells to Activate the Cancer-Specific Protective Immunity and Inhibit the Cancer Growth in a Murine Model of Colorectal Cancer.
Rajesh Mani, Chloe G Martin, Kanal E Balu, Qingding Wang, Piotr Rychahou

Cells· January 2024

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Immunization with the amino-terminus region of dense granule protein 6 (GRA6) of Toxoplasma gondii activates CD8 cytotoxic T cells capable of removing tissue cysts of the parasite through antigen presentation by human HLA-A2.1.
Rajesh Mani, Corinne Mercier, Marie-France Delauw, Yasuhiro Suzuki

Microbes Infect· December 2023

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Dense granule protein 3 of plays a crucial role in the capability of the tissue cysts of the parasite to persist in the presence of anti-cyst CD8 T cells during the chronic stage of infection.
Rajesh Mani, Mohamed H Abdelaziz, Eri Ochiai, Qila Sa, Barbara A Fox

Front Immunol· November 2023

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Biomaterial-based platforms for modulating immune components against cancer and cancer stem cells.
Nimeet Desai, Uzma Hasan, Jeyashree K, Rajesh Mani, Meenakshi Chauhan

Acta Biomater· April 2023

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Human MHC class I molecule, HLA-A2.1, mediates activation of CD8 T cell IFN-γ production and the T cell-dependent protection against reactivation of cerebral infection.
Rajesh Mani, Mohamed H Abdelaziz, Alexandra Michelon, Yasuhiro Suzuki

Front Immunol· November 2022

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Biomimicking nanofibrous gelatin microspheres recreating the stem cell niche for their ex-vivo expansion and in-vivo like differentiation for injectable stem cell transplantation.
Nandini Sarviya, Suparna Mercy Basu, Rajesh Mani, Meenakshi Chauhan, Peter Kingshott

Biomater Adv· August 2022

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Deficiency in indoleamine-2, 3-dioxygenase induces upregulation of guanylate binding protein 1 and inducible nitric oxide synthase expression in the brain during cerebral infection with Toxoplasma gondii in genetically resistant BALB/c mice but not in genetically susceptible C57BL/6 mice.
Namrata Anand, Jenny Lutshumba, Megan Whitlow, Mohamed H Abdelaziz, Rajesh Mani

Microbes Infect· May 2022

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Co-Administration of Aluminium Hydroxide Nanoparticles and Protective Antigen Domain 4 Encapsulated Non-Ionic Surfactant Vesicles Show Enhanced Immune Response and Superior Protection against Anthrax.
Himanshu Gogoi, Rajesh Mani, Anshu Malik, Parveen Sehrawat, Rakesh Bhatnagar

Vaccines (Basel)· October 2020

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Crystalline and Amorphous Preparation of Aluminum Hydroxide Nanoparticles Enhances Protective Antigen Domain 4 Specific Immunogenicity and Provides Protection Against Anthrax.
Himanshu Gogoi, Rajesh Mani, Soumya Aggarwal, Anshu Malik, Manoj Munde

Int J Nanomedicine· May 2020

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Single-dose Ag85B-ESAT6-loaded poly(lactic--glycolic acid) nanoparticles confer protective immunity against tuberculosis.
Anshu Malik, Manish Gupta, Rajesh Mani, Rakesh Bhatnagar

Int J Nanomedicine· July 2019

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Trimethyl Chitosan Nanoparticles Encapsulated Protective Antigen Protects the Mice Against Anthrax.
Anshu Malik, Manish Gupta, Rajesh Mani, Himanshu Gogoi, Rakesh Bhatnagar

Front Immunol· May 2019

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A niosome formulation modulates the Th1/Th2 bias immune response in mice and also provides protection against anthrax spore challenge.
Himanshu Gogoi, Rajesh Mani, Rakesh Bhatnagar

Int J Nanomedicine· January 2019

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Adjuvant Potential of Poly-α-l-Glutamine from the Cell Wall of Mycobacterium tuberculosis.
Rajesh Mani, Manish Gupta, Anshu Malik, Ravi Tandon, Rajendra Prasad

Infect Immun· October 2018

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Influence of diet and dietary nanoparticles on gut dysbiosis.
Ziyu Jiang, Joe Antony Jacob, Jianyue Li, Xiahui Wu, Guoli Wei, Rajesh Mani

Microb Pathog· May 2018

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