Publications by authors named "Rajesh Narwal"

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Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo.
Darren J Schofield, Lorraine Irving, Laura Calo, Anna Bogstedt, Gareth Rees, Rajesh Narwal

Neurobiol Dis· December 2019

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Detecting bliss synergy in in vivo combination studies with a tumor kinetic model.
Wei Zhao, Paolo Vicini, Steven Novick, Judith Anderton, Gareth Davies, Rajesh Narwal

Pharm Stat· November 2019

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Prognostic Significance of Liver Metastasis in Durvalumab-Treated Lung Cancer Patients.
Sriram Sridhar, Luis Paz-Ares, Hao Liu, Kui Shen, Chris Morehouse, Rajesh Narwal

Clin Lung Cancer· November 2019

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Clinical Activity, Tolerability, and Long-Term Follow-Up of Durvalumab in Patients With Advanced NSCLC.
Scott J Antonia, Ani Balmanoukian, Julie Brahmer, Sai-Hong I Ou, Matthew D Hellmann, Rajesh Narwal

J Thorac Oncol· October 2019

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Exposure-Response Analysis of Overall Survival for Tremelimumab in Unresectable Malignant Mesothelioma: The Confounding Effect of Disease Status.
Paul Baverel, Lorin Roskos, Manasa Tatipalli, Nancy Lee, Paul Stockman, Rajesh Narwal

Clin Transl Sci· September 2019

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A QSP Model for Predicting Clinical Responses to Monotherapy, Combination and Sequential Therapy Following CTLA-4, PD-1, and PD-L1 Checkpoint Blockade.
Oleg Milberg, Chang Gong, Mohammad Jafarnejad, Imke H Bartelink, Bing Wang, Rajesh Narwal

Sci Rep· August 2019

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A Computational Model of Neoadjuvant PD-1 Inhibition in Non-Small Cell Lung Cancer.
Mohammad Jafarnejad, Chang Gong, Edward Gabrielson, Imke H Bartelink, Paolo Vicini, Rajesh Narwal

AAPS J· June 2019

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simulation of a clinical trial with anti-CTLA-4 and anti-PD-L1 immunotherapies in metastatic breast cancer using a systems pharmacology model.
Hanwen Wang, Oleg Milberg, Imke H Bartelink, Paolo Vicini, Bing Wang, Rajesh Narwal

R Soc Open Sci· May 2019

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MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer.
Yoshimi Endo Greer, Samuel F Gilbert, Brunilde Gril, Rajesh Narwal, Danielle L Peacock Brooks

Breast Cancer Res· February 2019

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Nullifying phosphatidic acid effect and controlling phospholipase D associated browning in litchi pericarp through combinatorial application of hexanal and inositol.
Bharat Bhushan, Satish Kumar, Manoj Kumar Mahawar, Kirti Jalgaonkar, Ajinath Shridhar Dukare, Rajesh Kumari Narwal

Sci Rep· February 2019

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Population Modeling of Tumor Kinetics and Overall Survival to Identify Prognostic and Predictive Biomarkers of Efficacy for Durvalumab in Patients With Urothelial Carcinoma.
Yanan Zheng, Rajesh Narwal, ChaoYu Jin, Paul G Baverel, Xiaoping Jin

Clin Pharmacol Ther· April 2018

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Population Pharmacokinetics of Durvalumab in Cancer Patients and Association With Longitudinal Biomarkers of Disease Status.
Paul G Baverel, Vincent F S Dubois, Chao Yu Jin, Yanan Zheng, Xuyang Song, Rajesh Narwal

Clin Pharmacol Ther· April 2018

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Sustainable Development Goals: Leveraging the Global Agenda for Driving Health Policy Reforms and Achieving Universal Health Coverage in India.
Rajeev Gera, Rajesh Narwal, Manish Jain, Gunjan Taneja, Sachin Gupta

Indian J Community Med· January 2018

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A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition.
Chang Gong, Oleg Milberg, Bing Wang, Paolo Vicini, Rajesh Narwal

J R Soc Interface· September 2017

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Phase II study of MEDI-575, an anti-platelet-derived growth factor-α antibody, in patients with recurrent glioblastoma.
Surasak Phuphanich, Jeffrey Raizer, Marc Chamberlain, Paola Canelos, Rajesh Narwal

J Neurooncol· January 2017

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Inactivation thermodynamics and iso-kinetic profiling for evaluating operational suitability of milk clotting enzyme immobilized in composite polymer matrix.
Rajesh Kumari Narwal, Bharat Bhushan, Ajay Pal, Sarla Popli Malhotra, Satish Kumar

Int J Biol Macromol· October 2016

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Has the Rate of Reduction in Infant Mortality Increased in India Since the Launch of National Rural Health Mission? Analysis of Time Trends 2000-2009 with Projection to 2015.
Rajesh Narwal, Lu Gram

Int J MCH AIDS· September 2016

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Development of Immunoassays for the Quantitative Assessment of Amyloid-β in the Presence of Therapeutic Antibody: Application to Pre-Clinical Studies.
Anna Bogstedt, Maria Groves, Keith Tan, Rajesh Narwal, Mary McFarlane

J Alzheimers Dis· June 2016

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Safety and antitumour activity of durvalumab plus tremelimumab in non-small cell lung cancer: a multicentre, phase 1b study.
Scott Antonia, Sarah B Goldberg, Ani Balmanoukian, Jamie E Chaft, Rachel E Sanborn, Rajesh Narwal

Lancet Oncol· March 2016

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Combinatorial approaches for controlling pericarp browning in Litchi (Litchi chinensis) fruit.
Bharat Bhushan, Ajay Pal, Rajesh Narwal, Vijay Singh Meena, Pritam Chand Sharma

J Food Sci Technol· September 2015

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A phase I dose-escalation study of MEDI-575, a PDGFRα monoclonal antibody, in adults with advanced solid tumors.
Carlos R Becerra, Paul Conkling, Nicholas Vogelzang, Hilary Wu, Shengyan Hong, Rajesh Narwal

Cancer Chemother Pharmacol· November 2014

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Sustained peripheral depletion of amyloid-β with a novel form of neprilysin does not affect central levels of amyloid-β.
Simon J Henderson, Christin Andersson, Rajesh Narwal, Juliette Janson, Tom J Goldschmidt

Brain· February 2014

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Preterm birth-associated neurodevelopmental impairment estimates at regional and global levels for 2010.
Hannah Blencowe, Anne C C Lee, Simon Cousens, Adil Bahalim, Rajesh Narwal

Pediatr Res· December 2013

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Population pharmacokinetics of sifalimumab, an investigational anti-interferon-α monoclonal antibody, in systemic lupus erythematosus.
Rajesh Narwal, Lorin K Roskos, Gabriel J Robbie

Clin Pharmacokinet· November 2013

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National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications.
Hannah Blencowe, Simon Cousens, Mikkel Z Oestergaard, Doris Chou, Ann-Beth Moller, Rajesh Narwal

Lancet· June 2012

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