Publications by authors named "Rajesh Viswanathan"

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Total synthesis of (-)-griseocazine D2 and D3.
Subhasish Pradhan, Rajesh Viswanathan

Org Biomol Chem· May 2025

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Development of Natural-Product-Inspired ABCB1 Inhibitors Through Regioselective Tryptophan C3-Benzylation.
Dona Mariya Vincent, Habib Mostafa, Anza Suneer, Sabhashina Radha Krishnan, Mingmin Ong, Rajesh Viswanathan

Chemistry· November 2024

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Exploring bat-inspired cyclic tryptophan diketopiperazines as ABCB1 Inhibitors.
Javier Yu Peng Koh, Yoko Itahana, Alexander Krah, Habib Mostafa, Mingmin Ong, Rajesh Viswanathan

Commun Chem· July 2024

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Unveiling an indole alkaloid diketopiperazine biosynthetic pathway that features a unique stereoisomerase and multifunctional methyltransferase.
Garrett Deletti, Sajan D Green, Caleb Weber, Kristen N Patterson, Swapnil S Joshi, Rajesh Viswanathan

Nat Commun· May 2023

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Trehalose helps the hunt for glassy water.
Rajesh Viswanathan

J Biosci· October 2022

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Biomimetic Total Synthesis of (+)-Nocardioazine B and Analogs.
Tushar M Khopade, Kalyani Ajayan, Dona Mariya Vincent, Amy L Lane, Rajesh Viswanathan

J Org Chem· September 2022

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Biocatalysts from cyanobacterial hapalindole pathway afford antivirulent isonitriles against MRSA.
Brittney M Bunn, Mizhi Xu, Chase M Webb, Rajesh Viswanathan

J Biosci· December 2021

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Bioinspired Brønsted Acid-Promoted Regioselective Tryptophan Isoprenylations.
Tushar M Khopade, Kalyani Ajayan, Swapnil S Joshi, Amy L Lane, Rajesh Viswanathan

ACS Omega· April 2021

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Structure-Guided Synthesis and Mechanistic Studies Reveal Sweetspots on Naphthyl Salicyl Hydrazone Scaffold as Non-Nucleosidic Competitive, Reversible Inhibitors of Human Ribonucleotide Reductase.
Sarah E Huff, Faiz Ahmad Mohammed, Mu Yang, Prashansa Agrawal, John Pink, Rajesh Viswanathan

J Med Chem· February 2018

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Phylogenetic sequence analysis and functional studies reveal compensatory amino acid substitutions in loop 2 of human ribonucleotide reductase.
Andrew J Knappenberger, Sneha Grandhi, Reena Sheth, Md Faiz Ahmad, Rajesh Viswanathan

J Biol Chem· October 2017

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Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule.
Md Faiz Ahmad, Intekhab Alam, Sarah E Huff, John Pink, Sheryl A Flanagan, Rajesh Viswanathan

Proc Natl Acad Sci U S A· August 2017

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Nucleoside Analogue Triphosphates Allosterically Regulate Human Ribonucleotide Reductase and Identify Chemical Determinants That Drive Substrate Specificity.
Andrew J Knappenberger, Md Faiz Ahmad, Rajesh Viswanathan, Chris G Dealwis, Michael E Harris

Biochemistry· October 2016

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Two Distinct Cyclodipeptide Synthases from a Marine Actinomycete Catalyze Biosynthesis of the Same Diketopiperazine Natural Product.
Elle D James, Bryan Knuckley, Norah Alqahtani, Suheel Porwal, Jisun Ban, Rajesh Viswanathan

ACS Synth Biol· July 2016

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Identification of Non-nucleoside Human Ribonucleotide Reductase Modulators.
Md Faiz Ahmad, Sarah E Huff, John Pink, Intekhab Alam, Andrew Zhang, Rajesh Viswanathan

J Med Chem· December 2015

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Correction: Synergism between genome sequencing, tandem mass spectrometry and bio-inspired synthesis reveals insights into nocardioazine B biogenesis.
Norah Alqahtani, Suheel K Porwal, Elle D James, Dana M Bis, Jonathan A Karty, Rajesh Viswanathan

Org Biomol Chem· September 2015

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Genome mining for natural product biosynthetic gene clusters in the Subsection V cyanobacteria.
Melinda L Micallef, Paul M D'Agostino, Deepti Sharma, Rajesh Viswanathan, Michelle C Moffitt

BMC Genomics· September 2015

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Synergism between genome sequencing, tandem mass spectrometry and bio-inspired synthesis reveals insights into nocardioazine B biogenesis.
Norah Alqahtani, Suheel K Porwal, Elle D James, Dana M Bis, Jonathan A Karty, Rajesh Viswanathan

Org Biomol Chem· July 2015

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Synthetic, potentiometric and spectroscopic studies of chelation between Fe(III) and 2,5-DHBA supports salicylate-mode of siderophore binding interactions.
Suheel K Porwal, Emilia Furia, Michael E Harris, Rajesh Viswanathan, L Devireddy

J Inorg Biochem· April 2015

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Characterization of the nocardiopsin biosynthetic gene cluster reveals similarities to and differences from the rapamycin and FK-506 pathways.
Dana M Bis, Yang H Ban, Elle D James, Norah Alqahtani, Rajesh Viswanathan

Chembiochem· April 2015

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Novel quorum-quenching agents promote methicillin-resistant Staphylococcus aureus (MRSA) wound healing and sensitize MRSA to β-lactam antibiotics.
David Kuo, Guanping Yu, Wyatt Hoch, Dean Gabay, Lisa Long, Rajesh Viswanathan

Antimicrob Agents Chemother· March 2015

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Regioselective cope rearrangement and prenyl transfers on indole scaffold mimicking fungal and bacterial dimethylallyltryptophan synthases.
Karthikeyan Thandavamurthy, Deepti Sharma, Suheel K Porwal, Dale Ray, Rajesh Viswanathan

J Org Chem· November 2014

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Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution of indole-isonitrile biosynthesis from cyanobacteria.
Melinda L Micallef, Deepti Sharma, Brittney M Bunn, Lena Gerwick, Rajesh Viswanathan

BMC Microbiol· August 2014

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Regulation of mammalian siderophore 2,5-DHBA in the innate immune response to infection.
Zhuoming Liu, Scott Reba, Wei-Dong Chen, Suheel Kumar Porwal, W Henry Boom, Rajesh Viswanathan

J Exp Med· June 2014

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Combinatorial synthesis and in vitro evaluation of a biaryl hydroxyketone library as antivirulence agents against MRSA.
Guanping Yu, David Kuo, Menachem Shoham, Rajesh Viswanathan

ACS Comb Sci· February 2014

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Synthesis of a suite of bioorthogonal glutathione S-transferase substrates and their enzymatic incorporation for protein immobilization.
Alden E Voelker, Rajesh Viswanathan

J Org Chem· October 2013

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