Publications by authors named "Rajkumar Savai"

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Plasma proteomic profiling and molecular clustering reveal immune-defined prognostic subtypes in lung adenocarcinoma.
Ujjwal Neogi, Anoop T Ambikan, Kati Turkowski, Marc A Schneider, Vanessa M Beutgen, Rajkumar Savai

Int J Cancer· February 2026

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Treatment of NSCLC after chemoimmunotherapy - are we making headway?
Martin Reck, Nikolaj Frost, Solange Peters, Bernard A Fox, Roberto Ferrara, Rajkumar Savai

Nat Rev Clin Oncol· November 2025

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Deficiency of Smooth Muscle ADAR1 Exacerbates Vascular Remodeling and Pulmonary Hypertension.
Yunhye Kim, Giovanni Maroli, Chen-Shan Chen Woodcock, Hyunbum Kim, Yu Liu, Rajkumar Savai

Circ Res· October 2025

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Living human lung slices for ex vivo modelling of lung cancer.
Siavash Mansouri, Annika Karger, Clemens Ruppert, Marc A Schneider, Andreas Weigert, Rajkumar Savai

JCI Insight· September 2025

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Macrophage fatty acid metabolism under chronic hypoxia shapes γδ T cell recruitment via CCL22.
Vanesa M Guerrero Ruiz, Aya Khabaza, Rebekka Bauer, Blerina Aliraj, Siavash Mansouri, Rajkumar Savai

iScience· August 2025

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Neoadjuvant anti-programmed death-1 immunotherapy by pembrolizumab in resectable non-small cell lung cancer: results of the NEOMUN trial.
Martin E Eichhorn, Benedikt Niedermaier, Pornpimol Charoentong, Laura V Klotz, Philip Baum, Rajkumar Savai

J Immunother Cancer· August 2025

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Echocardiographic Measure of Right Ventricular-Pulmonary Arterial Coupling Predicts Survival in Lung Cancer.
Zvonimir A Rako, Michael Cekay, Athiththan Yogeswaran, Selin Yildiz, Philipp F Arndt, Rajkumar Savai

Ann Am Thorac Soc· July 2025

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Lung tumor immunity: redirecting macrophages through infection-induced inflammation.
Öznur Aktay-Cetin, Soni Savai Pullamsetti, Susanne Herold, Rajkumar Savai

Trends Immunol· June 2025

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Transcriptomic profiling of granuloma in patients with cardiac sarcoidosis.
Praveen Gajawada, Stefan Günther, Andreas Rolf, Jamal Nabhanizadeh, Rajkumar Savai

Theranostics· June 2025

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Cell type-specific efferocytosis determines functional plasticity of alveolar macrophages.
Julian Better, Mohammad Estiri, Michael Wetstein, Learta Pervizaj-Oruqaj, Christina Malainou, Rajkumar Savai

Sci Immunol· May 2025

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RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α.
Hao Liu, Yongqin Tang, Anshu Singh, Joaquim Vong, Julio Cordero, Rajkumar Savai

Nat Commun· May 2025

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Host Plasma Microenvironment in Immunometabolically Impaired HIV Infection Leads to Dysregulated Monocyte Function and Synaptic Transmission Ex Vivo.
Flora Mikaeloff, Marco Gelpi, Alejandra Escós, Tianqi Wang, Soham Gupta, Rajkumar Savai

Adv Sci (Weinh)· April 2025

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Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.
Julianne S Funk, Maria Klimovich, Daniel Drangenstein, Ole Pielhoop, Pascal Hunold, Rajkumar Savai

Nat Genet· January 2025

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Decoding lysosome communication.
Soni Savai Pullamsetti, Rajkumar Savai

Science· January 2025

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Imperative role of adaptor proteins in macrophage toll-like receptor signaling pathways.
Aurelia Rughetti, Shreya Bharti, Rajkumar Savai, Spyridoula Barmpoutsi, Andreas Weigert

Future Sci OA· December 2024

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Impact of T Cell Ratios on Survival in Pleural Mesothelioma: Insights from Tumor Microenvironment Analysis.
Laura V Klotz, Andreas Weigert, Florian Eichhorn, Michael Allgäuer, Thomas Muley, Rajkumar Savai

Cancers (Basel)· October 2024

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Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non-Small Cell Lung Cancer. An Official American Thoracic Society Research Statement.
Seyed Javad Moghaddam, Rajkumar Savai, Ramin Salehi-Rad, Shreoshi Sengupta, Michael N Kammer

Am J Respir Crit Care Med· September 2024

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RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions.
Lisa M Weiss, Timothy Warwick, Simonida Zehr, Stefan Günther, Sebastian Wolf, Rajkumar Savai

Commun Biol· September 2024

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KRAS and TP53 co-mutation predicts benefit of immune checkpoint blockade in lung adenocarcinoma.
Jan Budczies, Eva Romanovsky, Martina Kirchner, Olaf Neumann, Miriam Blasi, Rajkumar Savai

Br J Cancer· August 2024

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Non-invasive surrogate markers of pulmonary hypertension are associated with poor survival in patients with cancer.
Michael Cekay, Philipp F Arndt, Johanna K Franken, Jochen Wilhelm, Soni Savai Pullamsetti, Rajkumar Savai

BMJ Open Respir Res· August 2024

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CRISPR/Cas-Mediated Knockdown of PD-L1 and KRAS in Lung Cancer Cells.
Summer A Abounar, Nefertiti A El-Nikhely, Kati Turkowski, Rajkumar Savai, Hesham Saeed

Int J Mol Sci· August 2024

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Endothelin and the tumor microenvironment: a finger in every pie.
Philipp F Arndt, Kati Turkowski, Michael J Cekay, Bastian Eul, Friedrich Grimminger, Rajkumar Savai

Clin Sci (Lond)· June 2024

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SIRT7 promotes lung cancer progression by destabilizing the tumor suppressor ARF.
Poonam Kumari, Shahriar Tarighi, Eva Fuchshuber, Luhan Li, Irene Fernández-Duran, Rajkumar Savai

Proc Natl Acad Sci U S A· June 2024

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Sanglifehrin A mitigates multiorgan fibrosis by targeting the collagen chaperone cyclophilin B.
Hope A Flaxman, Maria-Anna Chrysovergi, Hongwei Han, Farah Kabir, Rachael T Lister, Rajkumar Savai

JCI Insight· June 2024

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Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension.
Fatemeh Khassafi, Prakash Chelladurai, Chanil Valasarajan, Sreenath Reddy Nayakanti, Sandra Martineau, Rajkumar Savai, Soni Savai Pullamsetti

Nat Cardiovasc Res· October 2023

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