Publications by authors named "Rajkumar Vutukuri"

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Deletion of ABIN1-LIR motifs impairs hepatic lipid homeostasis and mitophagy via AMPK-TFEB axis in mice.
Lisa Sophie Huber, Rosetta Merline, Jinyang Zeng-Brouwers, Rajkumar Vutukuri, Nico Kraus

Am J Physiol Cell Physiol· November 2025

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Elevated Sphingosine Levels Suppress Profibrotic TGF-β Signaling via the PKC/miR-21/SMAD7 Axis in Sphingosine Kinase 2-Deficient Renal Fibroblasts and Unilateral Ureteral Obstruction-Induced Kidney Fibrosis.
Anke Oftring, Viktoria Wagner, Dominique Thomas, Lisa Sophie Huber, Gerd Geisslinger, Rajkumar Vutukuri

FASEB J· June 2025

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Correction: Yamarthi et al. Ink Mitigates Dehydroepiandrosterone-Induced Insulin Resistance in Mouse Model of Polycystic Ovarian Syndrome. 2024, , 408-419.
Prathyusha Yamarthi, Rama Satyasri Kotipalli, Samatasai Patnaik, Kv Veena, Muralidharan Kathirvel, Rajkumar Vutukuri

Pathophysiology· January 2025

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Targeting the Neuro-vascular Presynaptic Signalling in STROKE: Evidence and Therapeutic Implications.
Shimantika Maikap, Alexandra Lucaciu, Aheli Chakraborty, Roxane Isabelle Kestner, Rajkumar Vutukuri

Ann Neurosci· January 2025

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Atypical sphingosine-1-phosphate metabolites-biological implications of alkyl chain length.
Melanie Glueck, Alexandra Lucaciu, Julien Subburayalu, Roxane Isabelle Kestner, Waltraud Pfeilschifter, Rajkumar Vutukuri

Pflugers Arch· December 2024

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Ink Mitigates Dehydroepiandrosterone-Induced Insulin Resistance in Mouse Model of Polycystic Ovarian Syndrome.
Prathyusha Yamarthi, Rama Satyasri Kotipalli, Samatasai Patnaik, Kv Veena, Muralidharan Kathirvel, Rajkumar Vutukuri

Pathophysiology· August 2024

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BI-3231, an enzymatic inhibitor of HSD17B13, reduces lipotoxic effects induced by palmitic acid in murine and human hepatocytes.
Lucia Alcober-Boquet, Nico Kraus, Lisa Sophie Huber, Rajkumar Vutukuri, Dominik C Fuhrmann

Am J Physiol Cell Physiol· March 2024

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Reciprocal abrogation of PKM isoforms: contradictory outcomes and differing impact of splicing signal on CRISPR/Cas9 mediates gene editing in keratinocytes.
Simon P Nold, Khrystyna Sych, Gergely Imre, Dominik C Fuhrmann, Josef Pfeilschifter, Rajkumar Vutukuri

FEBS J· May 2023

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Expression of PKM2 in wound keratinocytes is coupled to angiogenesis during skin repair in vivo and in HaCaT keratinocytes in vitro.
Khrystyna Sych, Simon P Nold, Josef Pfeilschifter, Rajkumar Vutukuri, Jana Meisterknecht

J Mol Med (Berl)· February 2023

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The atypical sphingosine 1-phosphate variant, d16:1 S1P, mediates CTGF induction via S1P2 activation in renal cell carcinoma.
Melanie Glueck, Alexander Koch, Robert Brunkhorst, Nerea Ferreiros Bouzas, Sandra Trautmann, Rajkumar Vutukuri

FEBS J· September 2022

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Behind the Wall-Compartment-Specific Neovascularisation during Post-Stroke Recovery in Mice.
Anja Kolbinger, Roxane Isabelle Kestner, Lara Jencio, Tim J Schäufele, Rajkumar Vutukuri

Cells· May 2022

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Endothelial Sphingosine-1-Phosphate Receptor 4 Regulates Blood-Brain Barrier Permeability and Promotes a Homeostatic Endothelial Phenotype.
Lena Hansen, Niklas Lohfink, Rajkumar Vutukuri, Roxane-Isabelle Kestner, Sandra Trautmann

J Neurosci· March 2022

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A Sphingosine 1-Phosphate Gradient Is Linked to the Cerebral Recruitment of T Helper and Regulatory T Helper Cells during Acute Ischemic Stroke.
Alexandra Lucaciu, Hannah Kuhn, Sandra Trautmann, Nerea Ferreirós, Helmuth Steinmetz, Rajkumar Vutukuri

Int J Mol Sci· August 2020

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Gene Expression Dynamics at the Neurovascular Unit During Early Regeneration After Cerebral Ischemia/Reperfusion Injury in Mice.
Roxane-Isabelle Kestner, Franziska Mayser, Rajkumar Vutukuri, Lena Hansen, Stefan Günther

Front Neurosci· April 2020

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S1P d20:1, an endogenous modulator of S1P d18:1/S1P -dependent signaling.
Rajkumar Vutukuri, Alexander Koch, Sandra Trautmann, Yannick Schreiber, Dominique Thomas

FASEB J· March 2020

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Beta adrenoceptor blockade ameliorates impaired glucose tolerance and alterations of the cerebral ceramide metabolism in an experimental model of ischemic stroke.
Sebastian Luger, Annette Schwebler, Rajkumar Vutukuri, Nerea Ferreiros Bouzas, Sandra Labocha

Ther Adv Neurol Disord· April 2018

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Sphingosine Kinase 2 Modulates Retinal Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy.
Jeanette Eresch, Martin Stumpf, Alexander Koch, Rajkumar Vutukuri, Nerea Ferreirós

Invest Ophthalmol Vis Sci· February 2018

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Alteration of sphingolipid metabolism as a putative mechanism underlying LPS-induced BBB disruption.
Rajkumar Vutukuri, Robert Brunkhorst, Roxane-Isabelle Kestner, Lena Hansen, Nerea Ferreiros Bouzas

J Neurochem· January 2018

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Reliability of infarct volumetry: Its relevance and the improvement by a software-assisted approach.
Felix Friedländer, Ferdinand Bohmann, Max Brunkhorst, Ju-Hee Chae, Kavi Devraj, Rajkumar Vutukuri

J Cereb Blood Flow Metab· August 2017

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Angiopoietin-2-induced blood-brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling.
Stefanie Gurnik, Kavi Devraj, Jadranka Macas, Maiko Yamaji, Julia Starke, Rajkumar Vutukuri

Acta Neuropathol· May 2016

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Fingolimod for the treatment of neurological diseases-state of play and future perspectives.
Robert Brunkhorst, Rajkumar Vutukuri, Waltraud Pfeilschifter

Front Cell Neurosci· October 2014

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