Publications by authors named "Ralph Dileone"

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The GLP-1R Agonist Semaglutide Reduces Motivated Running and Alters Dopamine Dynamics in the Nucleus Accumbens.
Ethan P Foscue, Joseph R Trinko, Jaysen Lara Jiménez, Edward Kong, Summer L Thompson, Ralph J DiLeone

bioRxiv· October 2025

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In Vivo Positron Emission Tomography Imaging of Presynaptic Density Reveals Stress-Associated Synaptic Deficits Related to Behavioral and Molecular Alterations in Rats.
Ruth H Asch, Nira Hernandez Martin, Rolando Garcia-Milian, Krista Fowles, Ralph J DiLeone

Biol Psychiatry Cogn Neurosci Neuroimaging· September 2025

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The NMDAR positive allosteric modulator NYX-783 selectively blocks opioid withdrawal conditioned place aversion in mice.
Joseph R Trinko, Ethan Foscue, Deven M Diaz, Summer L Thompson, Robert T Malison, Ralph J DiLeone

bioRxiv· September 2025

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Disruptions in Reward-Guided Decision-Making Functions Are Predictive of Greater Oral Oxycodone Self-Administration in Male and Female Rats.
Kaitlyn LaRocco, Peroushini Villiamma, Justin Hill, Mara A Russell, Ralph J DiLeone

Biol Psychiatry Glob Open Sci· May 2025

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Vitamin D's Capacity to Increase Amphetamine-Induced Dopamine Release in Healthy Humans: A Clinical Translational [C]-PHNO Positron Emission Tomography Study.
Patrick D Worhunsky, Marcella M Mignosa, Jean-Dominique Gallezot, Brian Pittman, Nabeel B Nabulsi, Ralph J DiLeone

Biol Psychiatry· March 2025

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Xylazine induces dopamine release and augments the effects of fentanyl.
Joseph R Trinko, Ethan Foscue, Edward M Kong, Aakash Basu, Anouk M Corstens, Ralph J DiLeone

J Clin Invest· November 2024

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Sex differences in oxycodone-taking behaviors are linked to disruptions in reward-guided, decision-making functions.
Kaitlyn LaRocco, Peroushini Villiamma, Justin Hill, Mara A Russell, Ralph J DiLeone

bioRxiv· April 2024

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The endogenous opioid system in the medial prefrontal cortex mediates ketamine's antidepressant-like actions.
Cheng Jiang, Ralph J DiLeone, Christopher Pittenger, Ronald S Duman

Transl Psychiatry· February 2024

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The endogenous opioid system in the medial prefrontal cortex mediates ketamine's antidepressant-like actions.
Christopher Pittenger, Cheng Jiang, Ralph DiLeone, Ronald Duman

Res Sq· October 2023

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Brain responses to nutrients are severely impaired and not reversed by weight loss in humans with obesity: a randomized crossover study.
Katy A van Galen, Anouk Schrantee, Kasper W Ter Horst, Susanne E la Fleur, Jan Booij, Ralph J DiLeone

Nat Metab· June 2023

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Examining sex differences in responses to footshock stress and the role of the metabotropic glutamate receptor 5: an [F]FPEB and positron emission tomography study in rats.
Ruth H Asch, Santosh Pothula, Takuya Toyonaga, Krista Fowles, Stephanie M Groman, Ralph J DiLeone

Neuropsychopharmacology· February 2023

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Orexin 1 Receptor Antagonism in the Basolateral Amygdala Shifts the Balance From Pro- to Antistress Signaling and Behavior.
Jazmine D W Yaeger, Kevin T Krupp, Benjamin M Jacobs, Benard O Onserio, Brandon L Meyerink, Ralph J DiLeone

Biol Psychiatry· May 2022

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Positive modulation of N-methyl-D-aspartate receptors in the mPFC reduces the spontaneous recovery of fear.
Boyoung Lee, Santosh Pothula, Min Wu, Hyeyeon Kang, Matthew J Girgenti, Ralph J DiLeone

Mol Psychiatry· May 2022

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Cerebellar neurons that curb food consumption.
Richard Simerly, Ralph DiLeone

Nature· December 2021

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The response to prolonged fasting in hypothalamic serotonin transporter availability is blunted in obesity.
Katy A van Galen, Jan Booij, Anouk Schrantee, Sofie M Adriaanse, Unga A Unmehopa, Ralph J DiLeone

Metabolism· October 2021

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Bringing in the ACE(i): Angiotensin-Converting Enzyme Inhibitors as Antidepressants.
Brendan D Hare, Ralph J DiLeone

Biol Psychiatry· September 2020

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Medial Nucleus Accumbens Projections to the Ventral Tegmental Area Control Food Consumption.
Colin W Bond, Richard Trinko, Ethan Foscue, Kara Furman, Stephanie M Groman, Ralph J DiLeone

J Neurosci· June 2020

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Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice.
Meghan E Flanigan, Hossein Aleyasin, Long Li, C Joseph Burnett, Kenny L Chan, Ralph J DiLeone

Nat Neurosci· May 2020

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Ketamine increases vmPFC activity: Effects of (R)- and (S)-stereoisomers and (2R,6R)-hydroxynorketamine metabolite.
Brendan D Hare, Santosh Pothula, Ralph J DiLeone, Ronald S Duman

Neuropharmacology· April 2020

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Orbitofrontal Circuits Control Multiple Reinforcement-Learning Processes.
Stephanie M Groman, Colby Keistler, Alex J Keip, Emma Hammarlund, Ralph J DiLeone

Neuron· August 2019

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Optogenetic stimulation of medial prefrontal cortex Drd1 neurons produces rapid and long-lasting antidepressant effects.
Brendan D Hare, Ryota Shinohara, Rong Jian Liu, Santosh Pothula, Ralph J DiLeone

Nat Commun· January 2019

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Striatal dopamine regulates systemic glucose metabolism in humans and mice.
Kasper W Ter Horst, Nicolette M Lammers, Richard Trinko, Darren M Opland, Martijn Figee, Ralph J DiLeone

Sci Transl Med· May 2018

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Down-regulation of miRNAs in the brain and development of diet-induced obesity.
Jaime G Maldonado-Avilés, Douglas J Guarnieri, Xianglong Zhu, Ralph J DiLeone

Int J Dev Neurosci· February 2018

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Regulation of Alcohol Extinction and Cue-Induced Reinstatement by Specific Projections among Medial Prefrontal Cortex, Nucleus Accumbens, and Basolateral Amygdala.
Colby R Keistler, Emma Hammarlund, Jacqueline M Barker, Colin W Bond, Ralph J DiLeone

J Neurosci· April 2017

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Characterization of GABAergic marker expression in the chronic unpredictable stress model of depression.
Mounira Banasr, Ashley Lepack, Corey Fee, Vanja Duric, Jaime Maldonado-Aviles, Ralph DiLeone

Chronic Stress (Thousand Oaks)· February 2017

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