Publications by authors named "Ralph Gradisch"

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Free energy profile of the substrate-induced occlusion of the human serotonin transporter.
Leticia Alves da Silva, Erika Lazzarin, Ralph Gradisch, Amy Clarke, Thomas Stockner

J Neurochem· September 2024

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De novo variants in GABRA4 are associated with a neurological phenotype including developmental delay, behavioral abnormalities and epilepsy.
Samin A Sajan, Ralph Gradisch, Florian D Vogel, Alison J Coffey, Daria Salyakina

Eur J Hum Genet· August 2024

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Unveiling the crucial role of betaine: modulation of GABA homeostasis via SLC6A1 transporter (GAT1).
Manan Bhatt, Erika Lazzarin, Ana Sofia Alberto-Silva, Guido Domingo, Rocco Zerlotti, Ralph Gradisch

Cell Mol Life Sci· June 2024

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Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors.
Ralph Gradisch, Katharina Schlögl, Erika Lazzarin, Marco Niello, Julian Maier

Nat Commun· January 2024

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Persistent binding at dopamine transporters determines sustained psychostimulant effects.
Marco Niello, Spyridon Sideromenos, Ralph Gradisch, Ronan O Shea, Jakob Schwazer

Proc Natl Acad Sci U S A· February 2023

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Structural basis of organic cation transporter-3 inhibition.
Basavraj Khanppnavar, Julian Maier, Freja Herborg, Ralph Gradisch, Erika Lazzarin

Nat Commun· November 2022

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Occlusion of the human serotonin transporter is mediated by serotonin-induced conformational changes in the bundle domain.
Ralph Gradisch, Dániel Szöllősi, Marco Niello, Erika Lazzarin, Harald H Sitte

J Biol Chem· March 2022

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The role of the degenerate nucleotide binding site in type I ABC exporters.
Thomas Stockner, Ralph Gradisch, Lutz Schmitt

FEBS Lett· December 2020

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Allosteric Modulation of Neurotransmitter Transporters as a Therapeutic Strategy.
Marco Niello, Ralph Gradisch, Claus Juul Loland, Thomas Stockner, Harald H Sitte

Trends Pharmacol Sci· July 2020

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