Publications by authors named "Ralph Patrick"

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Regenerative medicine approaches for the treatment of spinal cord injuries: Progress and challenges.
Patrick C Ralph, Sung-Woo Choi, Min Jung Baek, Sang Jin Lee

Acta Biomater· November 2024

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The generation of stable microvessels in ischemia is mediated by endothelial cell derived TRAIL.
Siân P Cartland, Manisha S Patil, Elaina Kelland, Natalie Le, Lauren Boccanfuso, Ralph Patrick

Sci Adv· October 2024

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The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening.
Ralph Patrick, Marina Naval-Sanchez, Nikita Deshpande, Yifei Huang, Jingyu Zhang

Cell Metab· August 2024

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Novel Mouse Model for Selective Tagging, Purification, and Manipulation of Cardiac Myofibroblasts.
Vaibhao Janbandhu, Vikram Tallapragada, Jinyuan Vero Li, Bharti Shewale, Shila Ghazanfar, Ralph Patrick

Circulation· June 2024

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Integration mapping of cardiac fibroblast single-cell transcriptomes elucidates cellular principles of fibrosis in diverse pathologies.
Ralph Patrick, Vaibhao Janbandhu, Vikram Tallapragada, Shannon S M Tan, Emily E McKinna

Sci Adv· June 2024

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Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction.
Sean A Hardy, Laura Liesinger, Ralph Patrick, Maria Poettler, Lavinia Rech

JACC Basic Transl Sci· December 2023

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Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction.
Lucy A Murtha, Sean A Hardy, Nishani S Mabotuwana, Mark J Bigland, Taleah Bailey, Ralph Patrick

Sci Rep· September 2023

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Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line.
Mahdi Moradi Marjaneh, Edwin P Kirk, Ralph Patrick, Dimuthu Alankarage, David T Humphreys

Elife· June 2023

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Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release.
Larisa I Labzin, Keng Yih Chew, Kathrin Eschke, Xiaohui Wang, Tyron Esposito, Ralph Patrick

Sci Signal· April 2023

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Cardiac fibroblast heterogeneity and dynamics through the lens of single-cell dual 'omics.
Richard P Harvey, Ralph Patrick, Vaibhao Janbandhu, Osvaldo Contreras

Cardiovasc Res· May 2022

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Effect of Alginate Microbead Encapsulation of Placental Mesenchymal Stem Cells on Their Immunomodulatory Function.
Fatma Khalil, Abdelrahman Alwan, Patrick Ralph, Soha Soliman, Eman A Abdelrahim

Ann Biomed Eng· March 2022

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Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction.
Vaibhao Janbandhu, Vikram Tallapragada, Ralph Patrick, Yanzhen Li, Dhanushi Abeygunawardena

Cell Stem Cell· February 2022

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Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction.
Lukas S Tombor, David John, Simone F Glaser, Guillermo Luxán, Elvira Forte, Ralph Patrick

Nat Commun· January 2021

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Sierra: discovery of differential transcript usage from polyA-captured single-cell RNA-seq data.
Ralph Patrick, David T Humphreys, Vaibhao Janbandhu, Alicia Oshlack, Joshua W K Ho

Genome Biol· July 2020

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Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch.
Santosh K Mishra, Joshua J Wheeler, Saumitra Pitake, Huiping Ding, Changyu Jiang, Patrick Ralph

Cell Rep· April 2020

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Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart.
Ramon Vidal, Julian Uwe Gabriel Wagner, Caroline Braeuning, Cornelius Fischer, Ralph Patrick

JCI Insight· November 2019

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Correction: Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk (doi:10.1242/dev.178673).
Alexander N Combes, Belinda Phipson, Kynan T Lawlor, Aude Dorison, Ralph Patrick

Development· July 2019

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Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk.
Alexander N Combes, Belinda Phipson, Kynan T Lawlor, Aude Dorison, Ralph Patrick

Development· June 2019

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Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury.
Nona Farbehi, Ralph Patrick, Aude Dorison, Munira Xaymardan, Vaibhao Janbandhu

Elife· March 2019

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Identification of active signaling pathways by integrating gene expression and protein interaction data.
Md Humayun Kabir, Ralph Patrick, Joshua W K Ho, Michael D O'Connor

BMC Syst Biol· December 2018

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Atopic Dermatitis Linked Cytokine Interleukin-31 Induced Itch Mediated via a Neuropeptide Natriuretic Polypeptide B.
Saumitra Pitake, Patrick C Ralph, Jennifer DeBrecht, Santosh K Mishra

Acta Derm Venereol· August 2018

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PhosphoPICK-SNP: quantifying the effect of amino acid variants on protein phosphorylation.
Ralph Patrick, Bostjan Kobe, Kim-Anh Lê Cao, Mikael Bodén

Bioinformatics· June 2017

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Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta.
Lyad Zamir, Reena Singh, Elisha Nathan, Ralph Patrick, Oren Yifa, Patrick Pl Tam

Elife· March 2017

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Prediction of kinase-specific phosphorylation sites through an integrative model of protein context and sequence.
Ralph Patrick, Coralie Horin, Bostjan Kobe, Kim-Anh Lê Cao, Mikael Bodén

Biochim Biophys Acta· November 2016

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PhosphoPICK: modelling cellular context to map kinase-substrate phosphorylation events.
Ralph Patrick, Kim-Anh Lê Cao, Bostjan Kobe, Mikael Bodén

Bioinformatics· February 2015

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