Publications by authors named "Ramdas Baskar"

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Targeting IL-1/IRAK1/4 signaling in acute myeloid leukemia stem cells following treatment and relapse.
Tzu-Chieh Ho, Mark W LaMere, Hiroki Kawano, Daniel K Byun, Elizabeth A LaMere, Baskar Ramdas

Leukemia· December 2025

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Suppression of Rho-associated kinase 1 (ROCK1) promotes human hematopoietic stem cell expansion by attenuating mitochondrial fission.
Xuepeng Wang, Baskar Ramdas, Ramesh Kumar, Ji Zhang, Reuben Kapur

Leukemia· November 2025

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Publisher Correction: Suppression of Rho-associated kinase 1 (ROCK1) promotes human hematopoietic stem cell expansion by attenuating mitochondrial fission.
Xuepeng Wang, Baskar Ramdas, Ramesh Kumar, Ji Zhang, Reuben Kapur

Leukemia· November 2025

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Granulopoietic Dysregulation in a Patient-Tailored Mouse Model of Barth Syndrome.
Elizabeth A Sierra Potchanant, Maegan L Capitano, Donna M Edwards, Baskar Ramdas, Scott Cooper

Stem Cell Rev Rep· October 2025

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Correction to: Granulopoietic Dysregulation in a Patient-Tailored Mouse Model of Barth Syndrome.
Elizabeth A Sierra Potchanant, Maegan L Capitano, Donna M Edwards, Baskar Ramdas, Scott Cooper

Stem Cell Rev Rep· September 2025

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Dual targeting of tumoral cells and immune microenvironment by blocking the IL-33/IL1RL1 pathway.
Denggang Fu, Hua Jiang, Alan Long, Ella Harris, Hongfen Guo, Baskar Ramdas

Nat Commun· July 2025

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ST2/IL-33 axis blockade inhibits regulatory T cell cytotoxicity towards CD8 T cells in the leukemic niche.
Hua Jiang, Denggang Fu, Santhosh Kumar Pasupuleti, Baskar Ramdas, Alan Long

Nat Commun· July 2025

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Multiplex imaging of murine bone marrow using Phenocycler 2.0™.
Sonali J Karnik, Connor Gulbronson, Paige C Jordan, Rahul Kanumuri, Baskar Ramdas

Leukemia· June 2025

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Alkynyl nicotinamides show antileukemic activity in drug-resistant acute myeloid leukemia.
Baskar Ramdas, Neetu Dayal, Ruchi Pandey, Elizabeth Larocque, Rahul Kanumuri

J Clin Invest· June 2024

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Obesity-induced inflammation exacerbates clonal hematopoiesis.
Santhosh Kumar Pasupuleti, Baskar Ramdas, Sarah S Burns, Lakshmi Reddy Palam, Rahul Kanumuri

J Clin Invest· June 2023

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Loss of Dnmt3a impairs hematopoietic homeostasis and myeloid cell skewing via the PI3Kinase pathway.
Lakshmi Reddy Palam, Baskar Ramdas, Katelyn Pickerell, Santhosh Kumar Pasupuleti, Rahul Kanumuri

JCI Insight· May 2023

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Potential clinical use of azacitidine and MEK inhibitor combination therapy in PTPN11-mutated juvenile myelomonocytic leukemia.
Santhosh Kumar Pasupuleti, Karen Chao, Baskar Ramdas, Rahul Kanumuri, Lakshmi Reddy Palam

Mol Ther· April 2023

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Physioxia-induced downregulation of Tet2 in hematopoietic stem cells contributes to enhanced self-renewal.
Arafat Aljoufi, Chi Zhang, James Ropa, Wennan Chang, Lakshmi Reddy Palam, Baskar Ramdas

Blood· September 2022

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Combined heterozygosity of FLT3 ITD, TET2, and DNMT3A results in aggressive leukemia.
Baskar Ramdas, Palam Lakshmi Reddy, Raghuveer Singh Mali, Santhosh Kumar Pasupuleti, Ji Zhang

JCI Insight· September 2022

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Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells.
Baskar Ramdas, Lisa Deng Yuen, Lakshmi Reddy Palam, Roshini Patel, Santhosh Kumar Pasupuleti

Mol Ther· July 2022

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Targeting SHP2 phosphatase in hematological malignancies.
Rahul Kanumuri, Santhosh Kumar Pasupuleti, Sarah S Burns, Baskar Ramdas, Reuben Kapur

Expert Opin Ther Targets· April 2022

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An IL-9-pulmonary macrophage axis defines the allergic lung inflammatory environment.
Yongyao Fu, Jocelyn Wang, Baohua Zhou, Abigail Pajulas, Hongyu Gao, Baskar Ramdas

Sci Immunol· February 2022

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SSMD: a semi-supervised approach for a robust cell type identification and deconvolution of mouse transcriptomics data.
Xiaoyu Lu, Szu-Wei Tu, Wennan Chang, Changlin Wan, Jiashi Wang, Baskar Ramdas

Brief Bioinform· July 2021

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Hyperglycemia cooperates with Tet2 heterozygosity to induce leukemia driven by proinflammatory cytokine-induced lncRNA Morrbid.
Zhigang Cai, Xiaoyu Lu, Chi Zhang, Sai Nelanuthala, Fabiola Aguilera, Baskar Ramdas

J Clin Invest· January 2021

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Driver Mutations in Leukemia Promote Disease Pathogenesis through a Combination of Cell-Autonomous and Niche Modulation.
Baskar Ramdas, Raghuveer Singh Mali, Lakshmi Reddy Palam, Ruchi Pandey, Zhigang Cai

Stem Cell Reports· July 2020

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Author Correction: Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.
Sisi Chen, Qiang Wang, Hao Yu, Maegan L Capitano, Sasidhar Vemula, Baskar Ramdas

Nat Commun· July 2020

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Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells.
Zhigang Cai, Fabiola Aguilera, Baskar Ramdas, Swapna Vidhur Daulatabad, Rajneesh Srivastava

Cell Rep· June 2020

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SHP2 inhibition reduces leukemogenesis in models of combined genetic and epigenetic mutations.
Ruchi Pandey, Baskar Ramdas, Changlin Wan, George Sandusky, Morvarid Mohseni

J Clin Invest· December 2019

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Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.
Sisi Chen, Qiang Wang, Hao Yu, Maegan L Capitano, Sasidhar Vemula, Baskar Ramdas

Nat Commun· December 2019

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Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis.
Zhigang Cai, Jonathan J Kotzin, Baskar Ramdas, Sisi Chen, Sai Nelanuthala

Cell Stem Cell· December 2018

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