Publications by authors named "Ramiro Jover"

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Ontogeny of drug-induced fatty liver disease (DIFLD): from key initiating events to disease phenotypes.
Ernesto López-Pascual, Marta Moreno-Torres, Erika Moro, Anna Rapisarda, Rita Ortega-Vallbona, Ramiro Jover

Arch Toxicol· December 2025

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Unravelling drug-induced hepatic steatosis: Clinical sub-phenotypes, outcome prediction, and identification of high-concern drugs and hazardous chemical attributes.
Marta Moreno-Torres, Ernesto López-Pascual, Erika Moro, Anna Rapisarda, Birgitte Lindeman, Ramiro Jover

Biomed Pharmacother· October 2025

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Modulatory effects of CNNM4 on protein- l -isoaspartyl- O -methyltransferase repair function during alcohol-induced hepatic damage.
Irene González-Recio, Naroa Goikoetxea-Usandizaga, Claudia M Rejano-Gordillo, Carolina Conter, Rubén Rodríguez Agudo, Ramiro Jover

Hepatology· August 2025

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Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding.
Luiz Ladeira, Anouk Verhoeven, Jonas van Ertvelde, Jian Jiang, Alessio Gamba, Ramiro Jover

Front Toxicol· July 2025

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Mapping physiology: A systems biology approach for the development of alternative methods in toxicology.
Bernard Staumont, Luiz Ladeira, Alessio Gamba, Harm J Heusinkveld, Aldert Piersma, Ramiro Jover

ALTEX· April 2025

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A microRNA signature for valproate-induced steatosis in human hepatocytes and its application to predict fatty liver in paediatric epileptic patients on valproate therapy.
Polina Soluyanova, Marta Del Pozo, Erika Moro-Castaño, Ana V Marco-Hernández, José V Castell, Ramiro Jover

Toxicology· December 2024

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The Development of a Non-Invasive Screening Method Based on Serum microRNAs to Quantify the Percentage of Liver Steatosis.
Polina Soluyanova, Guillermo Quintás, Álvaro Pérez-Rubio, Iván Rienda, Erika Moro, Ramiro Jover

Biomolecules· November 2024

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A quantitative weight-of-evidence method for confidence assessment of adverse outcome pathway networks: A case study on chemical-induced liver steatosis.
Anouk Verhoeven, Jonas van Ertvelde, Joost Boeckmans, Alexandra Gatzios, Ramiro Jover

Toxicology· June 2024

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Corrigendum to "Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support" [Biomed. Pharmacother. 174 (2024) 116530].
Marta Moreno-Torres, Ernesto López-Pascual, Anna Rapisarda, Guillermo Quintás, Annika Drees, Ramiro Jover

Biomed Pharmacother· June 2024

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Idiosyncratic Drug-Induced Liver Injury and Amoxicillin-Clavulanate: Spotlight on Gut Microbiota, Fecal Metabolome and Bile Acid Profile in Patients.
Sara Román-Sagüillo, Raisa Quiñones Castro, María Juárez-Fernández, Polina Soluyanova, Camilla Stephens, Ramiro Jover

Int J Mol Sci· June 2024

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Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support.
Marta Moreno-Torres, Ernesto López-Pascual, Anna Rapisarda, Guillermo Quintás, Annika Drees, Ramiro Jover

Biomed Pharmacother· May 2024

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Drug-Induced Fatty Liver Disease (DIFLD): A Comprehensive Analysis of Clinical, Biochemical, and Histopathological Data for Mechanisms Identification and Consistency with Current Adverse Outcome Pathways.
Ernesto López-Pascual, Ivan Rienda, Judith Perez-Rojas, Anna Rapisarda, Guillem Garcia-Llorens, Ramiro Jover

Int J Mol Sci· May 2024

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Exploring Individual Variability in Drug-Induced Liver Injury (DILI) Responses through Metabolomic Analysis.
Marta Moreno-Torres, Guillermo Quintás, Teresa Martínez-Sena, Ramiro Jover, José V Castell

Int J Mol Sci· March 2024

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Cluster-Partial Least Squares (c-PLS) regression analysis: Application to miRNA and metabolomic data.
Julia Kuligowski, Álvaro Pérez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Pérez-Rojas, Ramiro Jover

Anal Chim Acta· January 2024

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Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1.
Rubén Rodríguez-Agudo, Irene González-Recio, Marina Serrano-Maciá, Miren Bravo, Petar Petrov, Ramiro Jover

JHEP Rep· January 2024

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Optimization of an adverse outcome pathway network on chemical-induced cholestasis using an artificial intelligence-assisted data collection and confidence level quantification approach.
Jonas van Ertvelde, Anouk Verhoeven, Amy Maerten, Axelle Cooreman, Bruna Dos Santos Rodrigues, Ramiro Jover

J Biomed Inform· September 2023

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Gut Microbiota and Plasma Bile Acids Associated with Non-Alcoholic Fatty Liver Disease Resolution in Bariatric Surgery Patients.
Álvaro Pérez-Rubio, Polina Soluyanova, Erika Moro, Guillermo Quintás, Iván Rienda, Ramiro Jover

Nutrients· July 2023

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Enhancing the accuracy of mid-infrared spectroscopy-based liver steatosis quantification using digital image analysis as a reference.
Iván Rienda, Isabel Ten-Doménech, Erika Moro, Marta Moreno-Torres, Judith Pérez-Rojas, Ramiro Jover

Analyst· June 2023

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Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage.
Irene González-Recio, Jorge Simón, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, Maria Mercado-Gómez, Ramiro Jover

Nat Commun· November 2022

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The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes.
Maria Mercado-Gómez, Endika Prieto-Fernández, Naroa Goikoetxea-Usandizaga, Laura Vila-Vecilla, Mikel Azkargorta, Ramiro Jover

Commun Biol· August 2022

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Quantitative Prediction of Steatosis in Patients with Non-Alcoholic Fatty Liver by Means of Hepatic MicroRNAs Present in Serum and Correlating with Hepatic Fat.
Guillermo Quintás, Florian Caiment, Iván Rienda, Judith Pérez-Rojas, Eugenia Pareja, Ramiro Jover

Int J Mol Sci· August 2022

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Valproate and Short-Chain Fatty Acids Activate Transcription of the Human Vitamin D Receptor Gene through a Proximal GC-Rich DNA Region Containing Two Putative Sp1 Binding Sites.
Marta Moreno-Torres, Carla Guzmán, Petar D Petrov, Ramiro Jover

Nutrients· June 2022

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PTEN Deletion in Adult Mice Induces Hypoinsulinemia With Concomitant Low Glucose Levels.
Maria Crespo-Masip, Aurora Pérez-Gómez, Carla Guzmán, Sandra Rayego, Nuria Doladé, Ramiro Jover

Front Endocrinol (Lausanne)· April 2022

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Elimination of Vitamin D Signaling Causes Increased Mortality in a Model of Overactivation of the Insulin Receptor: Role of Lipid Metabolism.
Maria Crespo-Masip, Aurora Perez-Gomez, Alicia Garcia-Carrasco, Ramiro Jover, Carla Guzmán

Nutrients· April 2022

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Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen.
Rubén Rodríguez-Agudo, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, Pablo Fernández-Tussy, David Fernández-Ramos, Ramiro Jover

Antioxidants (Basel)· April 2022

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