Publications by authors named "Randall Mrsny"

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Human Fc C2 domain modifies cholix transcytosis pathway to facilitate efficient oral therapeutic protein delivery.
Alistair Taverner, Tom Hunter, Julia Mackay, Valentyna Varenko, Kate Gridley, Randall J Mrsny

J Control Release· September 2025

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Discovery of mono-ADP ribosylating toxins with high structural homology to Pseudomonas exotoxin A.
Geoffrey Masuyer, Alistair Taverner, Julia MacKay, Ana Rita Lima Marques, Yuye Wang, Randall J Mrsny

Commun Biol· March 2025

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modelling of intramuscular injection site events.
Adam J S McCartan, Randall J Mrsny

Expert Opin Drug Deliv· August 2024

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Hydrogel formats to model potential drug interactions occurring at the subcutaneous injection site.
Conor Gomes, Kate Gridley, Imogen Anastasiou, Bálint Sinkó, Randall J Mrsny

Eur J Pharm Biopharm· June 2024

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Structure-function analysis of tight junction-directed permeation enhancer PIP250.
Alistair Taverner, Khaled Almansour, Kate Gridley, Ana Rita Lima Marques, Julia MacKay, Randall J Mrsny

J Control Release· October 2023

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GRP75 as a functional element of cholix transcytosis.
Keyi Liu, Tom Hunter, Alistair Taverner, Kevin Yin, Julia MacKay, Randall J Mrsny

Tissue Barriers· January 2023

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Modelling intramuscular drug fate with tissue-relevant biomimetic hydrogels.
Adam McCartan, Julia Mackay, David Curran, Randall J Mrsny

Int J Pharm X· December 2022

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Does an Intradermal Vaccination for Monkeypox Make Sense?
Randall J Mrsny

AAPS J· October 2022

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Gut microbiota regulation of P-glycoprotein in the intestinal epithelium in maintenance of homeostasis.
Sage E Foley, Christine Tuohy, Merran Dunford, Michael J Grey, Heidi De Luca, Randall J Mrsny

Microbiome· September 2021

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Evaluating parameters affecting drug fate at the intramuscular injection site.
Adam J S McCartan, David W Curran, Randall J Mrsny

J Control Release· August 2021

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Re-Assessing PK/PD Issues for Oral Protein and Peptide Delivery.
Randall J Mrsny, Tahir A Mahmood

Pharmaceutics· July 2021

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Intestinal Transcytosis of a Protein Cargo and Nanoparticles Mediated by a Non-Toxic Form of Exotoxin A.
Ruiying Li, Floriane Laurent, Alistair Taverner, Julia Mackay, Paul A De Bank, Randall J Mrsny

Pharmaceutics· July 2021

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Are controlled release scientists doing enough for our environment?
Kinam Park, Randall Mrsny

J Control Release· April 2021

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Perspectives - Something new for JCR.
Randall J Mrsny

J Control Release· February 2021

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Cholix protein domain I functions as a carrier element for efficient apical to basal epithelial transcytosis.
Alistair Taverner, Julia MacKay, Floriane Laurent, Tom Hunter, Keyi Liu, Randall J Mrsny

Tissue Barriers· December 2020

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A Novel Fusion of IL-10 Engineered to Traffic across Intestinal Epithelium to Treat Colitis.
Nicole C Fay, Baby-Periyanayaki Muthusamy, Linh P Nyugen, Radhika C Desai, Alistair Taverner, Randall J Mrsny

J Immunol· December 2020

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Pseudopterosin and -Methyltylophorinidine Suppress Cell Growth in a 3D Spheroid Co-Culture Model of Pancreatic Ductal Adenocarcinoma.
Bailu Xie, Jan Hänsel, Vanessa Mundorf, Janina Betz, Irene Reimche, Randall J Mrsny

Bioengineering (Basel)· June 2020

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Accelerating the development of novel technologies and tools for the subcutaneous delivery of biotherapeutics.
David S Collins, Manuel Sánchez-Félix, Advait V Badkar, Randall Mrsny

J Control Release· May 2020

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Nanomedicines for the Delivery of Biologics.
John Wahlich, Arpan Desai, Francesca Greco, Kathryn Hill, Arwyn T Jones, Randall J Mrsny

Pharmaceutics· May 2019

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An intestinal paracellular pathway biased toward positively-charged macromolecules.
Khaled Almansour, Alistair Taverner, Jerrold R Turner, Ian M Eggleston, Randall J Mrsny

J Control Release· October 2018

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Intestinal P-glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis.
Rose L Szabady, Christopher Louissaint, Anneke Lubben, Bailu Xie, Shaun Reeksting, Randall J Mrsny

J Clin Invest· August 2018

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Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection.
Andrew Zukauskas, Randall J Mrsny, Paula Cortés Barrantes, Jerrold R Turner, John M Leong

mSphere· July 2018

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Mechanistic studies of a cell-permeant peptide designed to enhance myosin light chain phosphorylation in polarized intestinal epithelia.
Khaled Almansour, Alistair Taverner, Ian M Eggleston, Randall J Mrsny

J Control Release· June 2018

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Mucosal absorption of therapeutic peptides by harnessing the endogenous sorting of glycosphingolipids.
Maria Daniela Garcia-Castillo, Daniel J-F Chinnapen, Yvonne M Te Welscher, Rodrigo J Gonzalez, Samir Softic, Randall J Mrsny

Elife· May 2018

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In vitro model for predicting bioavailability of subcutaneously injected monoclonal antibodies.
Hanne Kinnunen Bown, Catherine Bonn, Stefan Yohe, Daniela Bumbaca Yadav, Thomas W Patapoff, Randall J Mrsny

J Control Release· March 2018

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