Publications by authors named "Randall Stoltz"

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Safety, Pharmacokinetics, and Pharmacodynamics of Trazpiroben (TAK-906), a Novel Selective D /D Receptor Antagonist: A Phase 1 Randomized, Placebo-Controlled Single- and Multiple-Dose Escalation Study in Healthy Participants.
Roger L Whiting, Borje Darpo, Chunlin Chen, Margaret Fletcher, Dan Combs, Randall R Stoltz

Clin Pharmacol Drug Dev· August 2021

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Safety, pharmacokinetics, and immunogenicity of a co-formulated cocktail of three human monoclonal antibodies targeting Ebola virus glycoprotein in healthy adults: a randomised, first-in-human phase 1 study.
Sumathi Sivapalasingam, Mohamed Kamal, Rabih Slim, Romana Hosain, Weiping Shao, Randall Stoltz

Lancet Infect Dis· August 2018

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CK-2127107 amplifies skeletal muscle response to nerve activation in humans.
Jinsy A Andrews, Timothy M Miller, Vipin Vijayakumar, Randall Stoltz, Joyce K James

Muscle Nerve· May 2018

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A Randomized Phase 1 Dose Escalation Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Trabodenoson in Healthy Adult Volunteers.
Alan Laties, Cadmus C Rich, Randall Stoltz, Vernon Humbert, Chaim Brickman

J Ocul Pharmacol Ther· October 2016

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The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women.
Stefan Zajic, Stefaan Rossenu, David Hreniuk, Filippos Kesisoglou, Jacqueline McCrea, Randall Stoltz

Drug Metab Dispos· September 2016

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A thorough QT study in the context of an uptitration regimen with selexipag, a selective oral prostacyclin receptor agonist.
Matthias Hoch, Borje Darpo, Tatiana Remenova, Randall Stoltz, Meijian Zhou

Drug Des Devel Ther· March 2016

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Inhaled loxapine and intramuscular lorazepam in healthy volunteers: a randomized placebo-controlled drug-drug interaction study.
Daniel A Spyker, James V Cassella, Randall R Stoltz, Paul P Yeung

Pharmacol Res Perspect· December 2015

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Effect of ceralifimod (ONO-4641) on lymphocytes and cardiac function: Randomized, double-blind, placebo-controlled trial with an open-label fingolimod arm.
Sonja Krösser, Peter Wolna, Tanya Z Fischer, Ursula Boschert, Randall Stoltz

J Clin Pharmacol· September 2015

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Effect of ponesimod, a selective S1P1 receptor modulator, on the QT interval in healthy individuals.
Matthias Hoch, Borje Darpo, Patrick Brossard, Meijian Zhou, Randall Stoltz

Basic Clin Pharmacol Toxicol· May 2015

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Tirasemtiv amplifies skeletal muscle response to nerve activation in humans.
Richard Hansen, Khalil G Saikali, Willis Chou, Alan J Russell, Michael M Chen, Randall R Stoltz

Muscle Nerve· December 2014

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Determining pharmacological selectivity of the kappa opioid receptor antagonist LY2456302 using pupillometry as a translational biomarker in rat and human.
Linda M Rorick-Kehn, Jennifer W Witcher, Stephen L Lowe, Celedon R Gonzales, Mary Ann Weller, Randall R Stoltz

Int J Neuropsychopharmacol· October 2014

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Safety, tolerability, and pharmacokinetic evaluation of single- and multiple-ascending doses of a novel kappa opioid receptor antagonist LY2456302 and drug interaction with ethanol in healthy subjects.
Stephen L Lowe, Conrad J Wong, Jennifer Witcher, Celedon R Gonzales, Gemma L Dickinson, Randall R Stoltz

J Clin Pharmacol· September 2014

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Multiple-dose pharmacokinetics and pharmacodynamics of sergliflozin etabonate, a novel inhibitor of glucose reabsorption, in healthy overweight and obese subjects: a randomized double-blind study.
Elizabeth K Hussey, Robert L Dobbins, Randall R Stoltz, Nancy L Stockman, Robin L O'Connor-Semmes

J Clin Pharmacol· June 2010

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Effect of casopitant, a novel NK-1 antagonist, on the pharmacokinetics of dolasetron and granisetron.
Laurel M Adams, Brendan Johnson, Ke Zhang, Lin Yue, Lyndon C Kirby, Randall Stoltz

Support Care Cancer· September 2009

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A thorough QTc study to assess the effect of sitagliptin, a DPP4 inhibitor, on ventricular repolarization in healthy subjects.
Daniel M Bloomfield, Rajesh Krishna, David Hreniuk, Lisa Hickey, Kalyan Ghosh, Randall Stoltz

J Clin Pharmacol· August 2009

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Metabolic disposition of [14C]bazedoxifene in healthy postmenopausal women.
Appavu Chandrasekaran, William E McKeand, Pamela Sullivan, William DeMaio, Randall Stoltz

Drug Metab Dispos· June 2009

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Minimal pharmacokinetic interaction between the human immunodeficiency virus nonnucleoside reverse transcriptase inhibitor etravirine and the integrase inhibitor raltegravir in healthy subjects.
Matt S Anderson, Thomas N Kakuda, William Hanley, Jutta Miller, James T Kost, Randall Stoltz

Antimicrob Agents Chemother· December 2008

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Effects of age, gender, and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers.
Angela Sansone-Parsons, Gopal Krishna, Jason Simon, Peter Soni, B Kantesaria, Randall Stoltz

Antimicrob Agents Chemother· February 2007

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Pharmacokinetics, metabolism and excretion of intravenous [l4C]-palonosetron in healthy human volunteers.
Randall Stoltz, Simona Parisi, Ajit Shah, Alberto Macciocchi

Biopharm Drug Dispos· November 2004

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Parecoxib sodium demonstrates gastrointestinal safety comparable to placebo in healthy subjects.
Stuart I Harris, Randall R Stoltz, Dianne LeComte, Richard C Hubbard

J Clin Gastroenterol· August 2004

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Pharmacokinetic and safety evaluation of palonosetron, a 5-hydroxytryptamine-3 receptor antagonist, in U.S. and Japanese healthy subjects.
Randall Stoltz, Jong-Chol Cyong, Ajit Shah, Simona Parisi

J Clin Pharmacol· May 2004

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Patient satisfaction with alosetron for the treatment of women with diarrhea-predominant irritable bowel syndrome.
Kevin Olden, Ronald G DeGarmo, Priti Jhingran, Barbara Bagby, Chris Decker, Randall R Stoltz

Am J Gastroenterol· December 2002

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Upper GI mucosal effects of parecoxib sodium in healthy elderly subjects.
Randall R Stoltz, Stuart I Harris, Michael E Kuss, Diane LeComte, Sheela Talwalker

Am J Gastroenterol· January 2002

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