Publications by authors named "Rania El-Botty"

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ESR1 Activating Mutations Confer Metabolic Vulnerabilities in ER+ Breast Cancer.
Francesca Bonechi, Marina Bacci, Nicla Lorito, Alfredo Smiriglia, Angela Subbiani

Cancer Res· November 2025

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Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers.
Maria M Haykal, Sylvie Rodrigues-Ferreira, Rania El Botty, Laura Sourd, Elisabetta Marangoni

Cancer Lett· June 2025

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Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors.
Daniele Musiani, Hatice Yücel, Marie Vallette, Annapaola Angrisani, Rania El Botty

Mol Cell· March 2025

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Acetalax and Bisacodyl for the Treatment of Triple-Negative Breast Cancer: A Combined Molecular and Preclinical Study.
William C Reinhold, Elisabetta Marangoni, Fathi Elloumi, Remi Montagne, Sudhir Varma

Cancer Res Commun· February 2025

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Evaluation of Combined Chemotherapy and Genomic-Driven Targeted Therapy in Patient-Derived Xenografts Identifies New Therapeutic Approaches in Squamous Non-Small-Cell Lung Cancer Patients.
Didier Decaudin, Fariba Némati, Julien Masliah Planchon, Agathe Seguin-Givelet, Marine Lefevre, Rania El-Botty

Cancers (Basel)· August 2024

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Acetyl-CoA carboxylase 1 controls a lipid droplet-peroxisome axis and is a vulnerability of endocrine-resistant ER breast cancer.
Marina Bacci, Nicla Lorito, Alfredo Smiriglia, Angela Subbiani, Francesca Bonechi

Sci Transl Med· February 2024

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Targeting Transcriptional Regulation with a CDK9 Inhibitor Suppresses Growth of Endocrine- and Palbociclib-Resistant ER+ Breast Cancers.
Arany Soosainathan, Marjan Iravani, Rania El-Botty, John Alexander, Laura Sourd

Cancer Res· January 2024

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HORMAD1 overexpression predicts response to anthracycline-cyclophosphamide and survival in triple-negative breast cancers.
Rania El-Botty, Sophie Vacher, Juliette Mainguené, Adrien Briaux, Sabrina Ibadioune

Mol Oncol· October 2023

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Oxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers.
Rania El-Botty, Ludivine Morriset, Elodie Montaudon, Zakia Tariq, Anne Schnitzler

Nat Commun· July 2023

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Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers.
Petra Ter Brugge, Sarah C Moser, Ivan Bièche, Petra Kristel, Sabrina Ibadioune, Rania El-Botty

Nat Commun· April 2023

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efficacy assessment of the CDK4/6 inhibitor palbociclib and the PLK1 inhibitor volasertib in human chordoma xenografts.
Thibault Passeri, Ahmed Dahmani, Julien Masliah-Planchon, Rania El Botty, Laura Courtois

Front Oncol· November 2022

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Dramatic In Vivo Efficacy of the EZH2-Inhibitor Tazemetostat in -Mutated Human Chordoma Xenograft.
Thibault Passeri, Ahmed Dahmani, Julien Masliah-Planchon, Adnan Naguez, Marine Michou

Cancers (Basel)· March 2022

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HRAS is a therapeutic target in malignant chemo-resistant adenomyoepithelioma of the breast.
Ivan Bièche, Florence Coussy, Rania El-Botty, Sophie Vacher, Sophie Château-Joubert

J Hematol Oncol· September 2021

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Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
Xing Yi Woo, Jessica Giordano, Anuj Srivastava, Zi-Ming Zhao, Michael W Lloyd

Nat Genet· May 2021

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Analysis of genomic and non-genomic signaling of estrogen receptor in PDX models of breast cancer treated with a combination of the PI3K inhibitor alpelisib (BYL719) and fulvestrant.
Julien Jacquemetton, Loay Kassem, Coralie Poulard, Ahmed Dahmani, Ludmilla De Plater

Breast Cancer Res· May 2021

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Response to mTOR and PI3K inhibitors in enzalutamide-resistant luminal androgen receptor triple-negative breast cancer patient-derived xenografts.
Florence Coussy, Marion Lavigne, Leanne de Koning, Rania El Botty, Fariba Nemati

Theranostics· April 2021

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High and synergistic activity between mTORC1 and PLK1 inhibition in adenocarcinoma NSCLC.
Elodie Montaudon, Rania El Botty, Sophie Vacher, Olivier Déas, Adnan Naguez

Oncotarget· April 2021

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In vitro bone metastasis dwelling in a 3D bioengineered niche.
Weijing Han, Rania El Botty, Elodie Montaudon, Laurent Malaquin, Frederic Deschaseaux

Biomaterials· February 2021

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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
Xing Yi Woo, Jessica Giordano, Anuj Srivastava, Zi-Ming Zhao, Michael W Lloyd

Nat Genet· January 2021

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PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance.
Elodie Montaudon, Joanna Nikitorowicz-Buniak, Laura Sourd, Ludivine Morisset, Rania El Botty

Nat Commun· August 2020

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BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers.
Florence Coussy, Rania El-Botty, Sophie Château-Joubert, Ahmed Dahmani, Elodie Montaudon

Sci Transl Med· February 2020

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Improvement of the anti-proliferative activity of the peptide ERα17p in MCF-7 breast cancer cells using nanodiamonds.
François Yip, Fariba Nemati, Rania El Botty, Mathilde Belnou, Didier Decaudin

Ann Pharm Fr· November 2019

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Interaction between IGF2-PI3K axis and cancer-associated-fibroblasts promotes anal squamous carcinogenesis.
Wulfran Cacheux, Astrid Lièvre, Sophie Richon, Sophie Vacher, Elsy El Alam

Int J Cancer· October 2019

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A large collection of integrated genomically characterized patient-derived xenografts highlighting the heterogeneity of triple-negative breast cancer.
Florence Coussy, Leanne de Koning, Marion Lavigne, Virginie Bernard, Berengere Ouine

Int J Cancer· October 2019

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PARP Inhibition Increases the Response to Chemotherapy in Uveal Melanoma.
Leanne de Koning, Didier Decaudin, Rania El Botty, André Nicolas, Guillaume Carita

Cancers (Basel)· May 2019

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