Publications by authors named "Raok Jeon"

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The new Bruton's tyrosine kinase inhibitors SPA8007 and SPA8009 reduce stemness and invasiveness of patient-derived glioblastoma tumorspheres.
Euna Jo, Eun Lee, Yoojung Oh, Dongkyu Lee, Byungho Lee, Yuesong Jeon, Raok Jeon

Transl Oncol· January 2026

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Design and Synthesis of Potent and Selective Urea-linked Benzenesulfonamide Analogs as Carbonic Anhydrase II Inhibitors.
Jisoo Kim, Eun Lee, Daniela Vullo, Chandra Bhushan Mishra, Claudiu T Supuran, Raok Jeon

Eur J Pharm Sci· October 2025

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Discovery of organosulfur-based selective HDAC8 inhibitors with anti-neuroblastoma activity.
Hyewon Cho, Eun Lee, Jisoo Kim, Soojeong Shin, Yoon-Jung Kim, Yong Hyun Jeon, Raok Jeon

Eur J Pharm Sci· December 2024

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Exploring structural and biological insights of TEAD through rational design and synthesis of niflumic acid derivatives.
Yong-Sung Choi, Yoon-Jung Kim, Yeram Jeon, Jong Soon Kang, Juhee Lee, Raok Jeon

J Enzyme Inhib Med Chem· December 2024

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Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation.
Chandra Bhushan Mishra, Shruti Shalini, Siddharth Gusain, Pawan Kumar, Shikha Kumari, Raok Jeon

Biomed Pharmacother· May 2024

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Targeting p21-activated kinase 4 (PAK4) with pyrazolo[3,4-]pyrimidine derivative SPA7012 attenuates hepatic ischaemia-reperfusion injury in mice.
Yuancheng Mao, Eun Lee, Xiaohui Yang, Eun Ju Bae, Raok Jeon

J Enzyme Inhib Med Chem· December 2022

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Therapeutic Efficacy of Novel HDAC Inhibitors SPA3052 and SPA3074 against Intestinal Inflammation in a Murine Model of Colitis.
Ji-In Yoon, Hyewon Cho, Raok Jeon, Mi-Kyung Sung

Pharmaceuticals (Basel)· December 2022

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The potential anti-amyloidogenic candidate, SPA1413, for Alzheimer's disease.
Seong Soo A An, Kyu Hwan Shim, Shinwoo Kang, Young Kyo Kim, Lalita Subedi, Raok Jeon

Br J Pharmacol· March 2022

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Anti-breast cancer action of carbonic anhydrase IX inhibitor 4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzylidene-hydrazinocarbonyl]-benzenesulfonamide (BSM-0004): and studies.
Chandra Bhushan Mishra, Raj Kumar Mongre, Amresh Prakash, Raok Jeon, Claudiu T Supuran

J Enzyme Inhib Med Chem· December 2021

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Structure-Activity Relationship of Phytoestrogen Analogs as ERα/β Agonists with Neuroprotective Activities.
Hye Won Cho, Hyo Jin Gim, Hua Li, Lalita Subedi, Sun Yeou Kim, Raok Jeon

Chem Pharm Bull (Tokyo)· June 2021

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Anti-inflammatory Effects of Seed Extract on Gelatinase-B (MMP-9) Regulation against Hyperglycemic Cardiomyocyte Stress.
Neha Atale, Chandra Bhushan Mishra, Shrey Kohli, Raj Kumar Mongre, Amresh Prakash, Raok Jeon

Oxid Med Cell Longev· May 2021

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Identifying the natural polyphenol catechin as a multi-targeted agent against SARS-CoV-2 for the plausible therapy of COVID-19: an integrated computational approach.
Chandra Bhushan Mishra, Preeti Pandey, Ravi Datta Sharma, Md Zubbair Malik, Raj Kumar Mongre, Raok Jeon

Brief Bioinform· March 2021

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Histone deacetylase 8 inhibition alleviates cholestatic liver injury and fibrosis.
Chang Hun Lee, Yunjung Choi, Hyewon Cho, In Hyuk Bang, Lihua Hao, Raok Jeon

Biochem Pharmacol· January 2021

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Discovery of Tricyclic Pyranochromenone as Novel Bruton's Tyrosine Kinase Inhibitors with in Vivo Antirheumatic Activity.
Hyewon Cho, Eun Lee, Hye Ah Kwon, Lee Seul, Hui-Jeon Jeon, Raok Jeon

Int J Mol Sci· October 2020

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Discovery of 5-Phenoxy-2-aminopyridine Derivatives as Potent and Selective Irreversible Inhibitors of Bruton's Tyrosine Kinase.
Eun Lee, Hyewon Cho, Da Kyung Lee, JuHyun Ha, Byeong Jo Choi, Ji Hye Jeong, Raok Jeon

Int J Mol Sci· October 2020

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SPA0355 prevents ovariectomy-induced bone loss in mice.
Sang Hoon Kim, Zhongkai Zhang, Young Jae Moon, Il Woon Park, Yong Gon Cho, Raok Jeon

Korean J Physiol Pharmacol· January 2019

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Identification of a Novel PPAR-γ Agonist through a Scaffold Tuning Approach.
Hyo Jin Gim, Yong-Sung Choi, Hua Li, Yoon-Jung Kim, Jae-Ha Ryu, Raok Jeon

Int J Mol Sci· October 2018

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Optimization and biological evaluation of 2-aminobenzothiazole derivatives as Aurora B kinase inhibitors.
Eun Lee, Ying An, Junhee Kwon, Keun Il Kim, Raok Jeon

Bioorg Med Chem· July 2017

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Selective Targeting of Cancer Stem Cells by 2-Aminodihydroquinoline Analogs.
Heejoo Park, Yeongji Yu, Hyejin Kim, Eun Lee, Hani Lee, Raok Jeon

Chem Pharm Bull (Tokyo)· April 2017

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Diarylheptanoids suppress proliferation of pancreatic cancer PANC-1 cells through modulating shh-Gli-FoxM1 pathway.
Guang-Zhi Dong, Ji Hye Jeong, Yu-Ih Lee, So Yoon Lee, Hui-Yuan Zhao, Raok Jeon

Arch Pharm Res· April 2017

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A lignan induces lysosomal dependent degradation of FoxM1 protein to suppress β-catenin nuclear translocation.
Guang-Zhi Dong, Ji Hye Jeong, Yu-Ih Lee, Yeong Eun Han, Jung Sook Shin, Raok Jeon

Sci Rep· April 2017

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Skin-Specific Deletion of Mis18α Impedes Proliferation and Stratification of Epidermal Keratinocytes.
Koog Chan Park, Minkyoung Lee, Yoon Jeon, Raok Jeon, Sung Hee Baek

J Invest Dermatol· February 2017

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Ajoene restored behavioral patterns and liver glutathione level in morphine treated C57BL6 mice.
Jaesuk Yun, Sergiy Oliynyk, Yeonju Lee, Jieun Kim, Kyunghwa Yun, Raok Jeon

Arch Pharm Res· January 2017

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Negative regulation of NOD1 mediated angiogenesis by PPARγ-regulated miR-125a.
Hyesoo Kang, Youngsook Park, Aram Lee, Hyemin Seo, Min Jung Kim, Ha-Neul Jeong, Raok Jeon

Biochem Biophys Res Commun· January 2017

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The synthetic ajoene analog SPA3015 induces apoptotic cell death through crosstalk between NF-κB and PPARγ in multidrug-resistant cancer cells.
Jee Won Hwang, Hyewon Cho, Jae Yeon Lee, Youngsic Jeon, Su-Nam Kim, Raok Jeon

Food Chem Toxicol· October 2016

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