Publications by authors named "Raphael A Aponte"

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A Novel Single-Site Mutation in the Catalytic Domain of Protoporphyrinogen Oxidase IX (PPO) Confers Resistance to PPO-Inhibiting Herbicides.
Gulab Rangani, Reiofeli A Salas-Perez, Raphael A Aponte, Michael Knapp, Ian R Craig

Front Plant Sci· May 2019

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Potent Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT) Featuring a Spirocyclic Scaffold.
Geoffrey Schwertz, Matthias C Witschel, Matthias Rottmann, Ubolsree Leartsakulpanich, Penchit Chitnumsub, Raphael A Aponte

ChemMedChem· May 2018

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Conformational Aspects in the Design of Inhibitors for Serine Hydroxymethyltransferase (SHMT): Biphenyl, Aryl Sulfonamide, and Aryl Sulfone Motifs.
Geoffrey Schwertz, Michelle S Frei, Matthias C Witschel, Matthias Rottmann, Ubolsree Leartsakulpanich, Raphael A Aponte

Chemistry· October 2017

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Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal Structures.
Geoffrey Schwertz, Matthias C Witschel, Matthias Rottmann, Roger Bonnert, Ubolsree Leartsakulpanich, Raphael A Aponte

J Med Chem· June 2017

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A new amino acid substitution (Ala-205-Phe) in acetolactate synthase (ALS) confers broad spectrum resistance to ALS-inhibiting herbicides.
James T Brosnan, Jose J Vargas, Gregory K Breeden, Logan Grier, Raphael A Aponte

Planta· January 2016

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Fine tuning of a biological machine: DnaK gains improved chaperone activity by altered allosteric communication and substrate binding.
Regina S Schweizer, Raphael A Aponte, Sabine Zimmermann, Annika Weber, Jochen Reinstein

Chembiochem· July 2011

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Directed evolution of the DnaK chaperone: mutations in the lid domain result in enhanced chaperone activity.
Raphael A Aponte, Sabine Zimmermann, Jochen Reinstein

J Mol Biol· May 2010

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Biochemical characterization of prephenate dehydrogenase from the hyperthermophilic bacterium Aquifex aeolicus.
Julie Bonvin, Raphael A Aponte, Maria Marcantonio, Sasha Singh, Dinesh Christendat

Protein Sci· June 2006

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