Publications by authors named "Raphael Geney"

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Design of a potent and selective dual JAK1/TYK2 inhibitor.
Oscar Mammoliti, Christel Menet, Céline Cottereaux, Javier Blanc, Ann De Blieck, Raphaël Geney

Bioorg Med Chem· November 2024

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Triazolopyridines as selective JAK1 inhibitors: from hit identification to GLPG0634.
Christel J Menet, Stephen R Fletcher, Guy Van Lommen, Raphael Geney, Javier Blanc

J Med Chem· November 2014

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Type II kinase inhibitors: an opportunity in cancer for rational design.
Javier Blanc, Raphaël Geney, Christel Menet

Anticancer Agents Med Chem· June 2013

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Advances in the discovery of selective JAK inhibitors.
Christel J Menet, Luc Van Rompaey, Raphaël Geney

Prog Med Chem· June 2013

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Design, synthesis, and biological evaluation of novel C14-C3'BzN-linked macrocyclic taxoids.
Liang Sun, Xudong Geng, Raphaël Geney, Yuan Li, Carlos Simmerling

J Org Chem· December 2008

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Improved Efficiency of Replica Exchange Simulations through Use of a Hybrid Explicit/Implicit Solvation Model.
Asim Okur, Lauren Wickstrom, Melinda Layten, Raphäel Geney, Kun Song

J Chem Theory Comput· March 2006

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Investigation of Salt Bridge Stability in a Generalized Born Solvent Model.
Raphaël Geney, Melinda Layten, Roberto Gomperts, Viktor Hornak, Carlos Simmerling

J Chem Theory Comput· January 2006

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Use of the tubulin bound paclitaxel conformation for structure-based rational drug design.
Raphaël Geney, Liang Sun, Paula Pera, Ralph J Bernacki, Shujun Xia

Chem Biol· March 2005

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Design and synthesis of de novo cytotoxic alkaloids through mimicking taxoid skeleton.
Xudong Geng, Raphaël Geney, Paula Pera, Ralph J Bernacki, Iwao Ojima

Bioorg Med Chem Lett· July 2004

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BMS-184476 Bristol-Myers Squibb.
Iwao Ojima, Raphaël Geney

Curr Opin Investig Drugs· June 2003

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109881 Aventis.
Iwao Ojima, Raphaël Geney

Curr Opin Investig Drugs· June 2003

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Medicinal chemistry and chemical biology of new generation taxane antitumor agents.
Iwao Ojima, Raphael Geney, Ioana Maria Ungureanu, Dansu Li

IUBMB Life· January 2003

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Overcoming multidrug resistance in taxane chemotherapy.
Raphaël Geney, loana Maria Ungureanu, Dansu Li, Iwao Ojima

Clin Chem Lab Med· September 2002

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Electronic effects on the regio- and enantioselectivity of the asymmetric aminohydroxylation of O-substituted 4-hydroxy-2-butenoates.
Chih-Yuan Chuang, Victor C Vassar, Zuping Ma, Raphaël Geney, Iwao Ojima

Chirality· April 2002

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