Publications by authors named "Raquel Seruca"

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Hereditary diffuse gastric cancer in progress: Comparative lessons from Lynch syndrome.
Joana Pereira, Luísa Carvalho, Soraia Melo, Patrícia Carneiro, Maria Sofia Fernandes, Raquel Seruca

Eur J Hum Genet· December 2025

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A novel computational approach to dissect the cytoskeletal architecture of cancer cells with invasive potential.
Diogo Fróis Vieira, Maria Sofia Fernandes, Joana Figueiredo, Soraia Melo, Ana Margarida Moreira, Raquel Seruca

Sci Rep· February 2025

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E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner.
Joana Pereira, Soraia Melo, Rui M Ferreira, Patrícia Carneiro, Vítor Yang, Raquel Seruca

Cell Commun Signal· February 2024

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The ECM and tissue architecture are major determinants of early invasion mediated by E-cadherin dysfunction.
Soraia Melo, Pilar Guerrero, Maurício Moreira Soares, José Rafael Bordin, Fátima Carneiro, Raquel Seruca

Commun Biol· November 2023

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Activation of Laminin γ2 by Helicobacter pylori Promotes Invasion and Survival of Gastric Cancer Cells With E-Cadherin Defects.
Rui M Ferreira, Joana Figueiredo, Ines Pinto-Ribeiro, Irene Gullo, Dionyssios N Sgouras, Raquel Seruca

J Infect Dis· December 2022

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Differential Impacts on Tensional Homeostasis of Gastric Cancer Cells Due to Distinct Domain Variants of E-Cadherin.
Han Xu, Katie A Bunde, Joana Figueiredo, Raquel Seruca, Michael L Smith

Cancers (Basel)· May 2022

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Author Correction: Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities.
Ana Teresa Pinto, Marta Laranjeiro Pinto, Ana Patrícia Cardoso, Cátia Monteiro, Marta Teixeira Pinto, Raquel Seruca

Sci Rep· March 2022

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Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression.
Ana M Moreira, Rui M Ferreira, Patrícia Carneiro, Joana Figueiredo, Hugo Osório, Raquel Seruca

Front Mol Biosci· March 2022

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Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells.
Joana Figueiredo, Rui M Ferreira, Han Xu, Margarida Gonçalves, André Barros-Carvalho, Raquel Seruca

Gastric Cancer· January 2022

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The Porto European Cancer Research Summit 2021.
Ulrik Ringborg, Anton Berns, Julio E Celis, Manuel Heitor, Josep Tabernero, Raquel Seruca

Mol Oncol· October 2021

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A machine learning approach for single cell interphase cell cycle staging.
Hemaxi Narotamo, Maria Sofia Fernandes, Ana Margarida Moreira, Soraia Melo, Raquel Seruca

Sci Rep· September 2021

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Germline G212E Missense Variant: Combining Clinical, In Vitro and In Vivo Strategies to Unravel Disease Burden.
Joana Figueiredo, Fátima Mercadillo, Soraia Melo, Alicia Barroso, Margarida Gonçalves, Raquel Seruca

Cancers (Basel)· August 2021

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Hereditary diffuse gastric cancer: updated clinical practice guidelines.
Vanessa R Blair, Maybelle McLeod, Fátima Carneiro, Daniel G Coit, Johanna L D'Addario, Raquel Seruca

Lancet Oncol· August 2020

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E-cadherin deregulation in breast cancer.
Giovanni Corso, Joana Figueiredo, Simone Pietro De Angelis, Federica Corso, Antonia Girardi, Raquel Seruca

J Cell Mol Med· June 2020

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Hereditary Gastric and Breast Cancer Syndromes Related to CDH1 Germline Mutation: A Multidisciplinary Clinical Review.
Giovanni Corso, Giacomo Montagna, Joana Figueiredo, Carlo La Vecchia, Uberto Fumagalli Romario, Raquel Seruca

Cancers (Basel)· June 2020

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The Extracellular Matrix: An Accomplice in Gastric Cancer Development and Progression.
Ana Margarida Moreira, Joana Pereira, Soraia Melo, Maria Sofia Fernandes, Patrícia Carneiro, Raquel Seruca

Cells· February 2020

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Targets the EPHA2 Receptor Tyrosine Kinase in Gastric Cells Modulating Key Cellular Functions.
Marina Leite, Miguel S Marques, Joana Melo, Marta T Pinto, Bruno Cavadas, Raquel Seruca

Cells· February 2020

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Targeting the Tumor Microenvironment: An Unexplored Strategy for Mutant KRAS Tumors.
Patrícia Dias Carvalho, Ana Luísa Machado, Flávia Martins, Raquel Seruca, Sérgia Velho

Cancers (Basel)· December 2019

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S100P is a molecular determinant of E-cadherin function in gastric cancer.
Patrícia Carneiro, Ana Margarida Moreira, Joana Figueiredo, Rita Barros, Patrícia Oliveira, Raquel Seruca

Cell Commun Signal· November 2019

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Targeting the PI3K Signalling as a Therapeutic Strategy in Colorectal Cancer.
Maria Sofia Fernandes, João Miguel Sanches, Raquel Seruca

Adv Exp Med Biol· July 2019

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Clinical spectrum and pleiotropic nature of germline mutations.
Joana Figueiredo, Soraia Melo, Patrícia Carneiro, Ana Margarida Moreira, Maria Sofia Fernandes, Raquel Seruca

J Med Genet· April 2019

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SRC inhibition prevents P-cadherin mediated signaling and function in basal-like breast cancer cells.
Ana Sofia Ribeiro, Ana Rita Nobre, Nuno Mendes, João Almeida, André Filipe Vieira, Raquel Seruca

Cell Commun Signal· November 2018

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E-cadherin signal sequence disruption: a novel mechanism underlying hereditary cancer.
Joana Figueiredo, Soraia Melo, Kimberley Gamet, Tanis Godwin, Susana Seixas, Raquel Seruca

Mol Cancer· August 2018

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Hereditary lobular breast cancer with an emphasis on E-cadherin genetic defect.
Giovanni Corso, Joana Figueiredo, Carlo La Vecchia, Paolo Veronesi, Gabriella Pravettoni, Raquel Seruca

J Med Genet· July 2018

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Geometric compensation applied to image analysis of cell populations with morphological variability: a new role for a classical concept.
Joana Figueiredo, Isabel Rodrigues, João Ribeiro, Maria Sofia Fernandes, Soraia Melo, Raquel Seruca

Sci Rep· July 2018

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