Publications by authors named "Raymond Pickles"

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SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation.
Diana M Battaglia, Claire E Post, Wenbo Yao, Angela Wahl, Lisa E Gralinski, Raymond J Pickles

Nat Microbiol· October 2025

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Airway epithelial SARS-CoV-2 infectious and repair responses: relationships to age, sex, and post-COVID pulmonary syndromes.
Hong Dang, Caitlin E Edwards, Takafumi Kato, Boris Reidel, Rita M Meganck, Raymond J Pickles

bioRxiv· September 2025

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Prolonged airway explant culture enables study of health, disease, and viral pathogenesis.
Rhianna E Lee-Ferris, Kenichi Okuda, Jacob R Galiger, Stephen A Schworer, Troy D Rogers, Raymond J Pickles

Sci Adv· April 2025

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Enhanced susceptibility of pediatric airway epithelium to respiratory syncytial virus infection.
Raymond J Pickles, Gang Chen, Scott H Randell

J Clin Invest· November 2024

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Impact of mAb-FcRn affinity on IgG transcytosis across human well-differentiated airway epithelium.
Kohei Togami, Whitney Wolf, Lucas C Olson, Madison Card, Limei Shen, Raymond J Pickles

Front Immunol· October 2024

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RSV infection of humanized lung-only mice induces pathological changes resembling severe bronchiolitis and bronchopneumonia.
Chandrav De, Raymond J Pickles, Wenbo Yao, Baolin Liao, Allison Boone

Front Virol· May 2024

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Viral airway injury promotes cell engraftment in an in vitro model of cystic fibrosis cell therapy.
Rhianna E Lee, Teresa M Mascenik, Sidra C Major, Jacob R Galiger, Emily Bulik-Sullivan, Raymond J Pickles

Am J Physiol Lung Cell Mol Physiol· March 2024

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Inhaled "Muco-Trapping" Monoclonal Antibody Effectively Treats Established Respiratory Syncytial Virus (RSV) Infections.
Morgan D McSweeney, Sarhad Alnajjar, Alison M Schaefer, Zach Richardson, Whitney Wolf, Raymond J Pickles

Adv Sci (Weinh)· March 2024

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Prolonged airway explant culture enables study of health, disease, and viral pathogenesis.
Rhianna E Lee-Ferris, Kenichi Okuda, Jacob R Galiger, Stephen A Schworer, Troy D Rogers, Raymond J Pickles

bioRxiv· February 2024

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Human T cells efficiently control RSV infection.
Chandrav De, Raymond J Pickles, Wenbo Yao, Baolin Liao, Allison Boone

JCI Insight· June 2023

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Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 h post infection.
Jason Pearson, Timothy Wessler, Alex Chen, Richard C Boucher, Ronit Freeman, Raymond Pickles

J Theor Biol· May 2023

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Pharmacokinetic-based failure of a detergent virucidal for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) nasal infections: A preclinical study and randomized controlled trial.
Charles R Esther, Kyle S Kimura, Yu Mikami, Caitlin E Edwards, Suman R Das, Raymond J Pickles

Int Forum Allergy Rhinol· September 2022

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Modeling insights into SARS-CoV-2 respiratory tract infections prior to immune protection.
Alexander Chen, Timothy Wessler, Katherine Daftari, Kameryn Hinton, Richard C Boucher, Raymond Pickles

Biophys J· May 2022

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Thiol-based chemical probes exhibit antiviral activity against SARS-CoV-2 via allosteric disulfide disruption in the spike glycoprotein.
Yunlong Shi, Ari Zeida, Caitlin E Edwards, Michael L Mallory, Santiago Sastre, Raymond J Pickles

Proc Natl Acad Sci U S A· February 2022

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Pharmacokinetic-based failure of a detergent virucidal for SARS-COV-2 nasal infections.
Charles R Esther, Kyle S Kimura, Yu Mikami, Caitlin E Edwards, Suman R Das, Raymond J Pickles

Res Sq· May 2021

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SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801.
Angela Wahl, Lisa E Gralinski, Claire E Johnson, Wenbo Yao, Martina Kovarova, Raymond J Pickles

Nature· March 2021

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Challenges and opportunities for antiviral monoclonal antibodies as COVID-19 therapy.
Carlos Cruz-Teran, Karthik Tiruthani, Morgan McSweeney, Alice Ma, Raymond Pickles

Adv Drug Deliv Rev· February 2021

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Learning from past failures: Challenges with monoclonal antibody therapies for COVID-19.
Samuel K Lai, Morgan D McSweeney, Raymond J Pickles

J Control Release· January 2021

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Acute SARS-CoV-2 Infection is Highly Cytopathic, Elicits a Robust Innate Immune Response and is Efficiently Prevented by EIDD-2801.
Angela Wahl, Lisa Gralinski, Claire Johnson, Wenbo Yao, Martina Kovarova, Raymond Pickles

Res Sq· September 2020

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Precision mouse models with expanded tropism for human pathogens.
Angela Wahl, Chandrav De, Maria Abad Fernandez, Erik M Lenarcic, Yinyan Xu, Raymond J Pickles

Nat Biotechnol· October 2019

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A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation.
Christopher C Stobart, Christina A Rostad, Zunlong Ke, Rebecca S Dillard, Cheri M Hampton, Raymond J Pickles

Nat Commun· December 2016

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SARS-like WIV1-CoV poised for human emergence.
Vineet D Menachery, Boyd L Yount, Amy C Sims, Kari Debbink, Sudhakar S Agnihothram, Raymond J Pickles

Proc Natl Acad Sci U S A· March 2016

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Effects of vitamin D on airway epithelial cell morphology and rhinovirus replication.
Rebecca A Brockman-Schneider, Raymond J Pickles, James E Gern

PLoS One· February 2015

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Respiratory syncytial virus (RSV) and its propensity for causing bronchiolitis.
Raymond J Pickles, John P DeVincenzo

J Pathol· January 2015

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RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction.
Rachael M Liesman, Ursula J Buchholz, Cindy L Luongo, Lijuan Yang, Alan D Proia, Raymond J Pickles

J Clin Invest· May 2014

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