Publications by authors named "Rebecka Hellsten"

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pSTAT3 Expression is Increased in Advanced Prostate Cancer in Post-Initiation of Androgen Deprivation Therapy.
Piotr Bialas, Tamae Kobayashi, Rebecka Hellsten, Agnieszka Krzyzanowska, Margareta Persson

Prostate· February 2025

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Editor's Note: Therapeutic Targeting of Nuclear γ-Tubulin in RB1-Negative Tumors.
Lisa Lindström, Bruno O Villoutreix, Sophie Lehn, Rebecka Hellsten, Elise Nilsson

Mol Cancer Res· November 2024

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The STAT3 inhibitor GPB730 enhances the sensitivity to enzalutamide in prostate cancer cells.
Rebecka Hellsten, Anna Stiehm, Macarena Palominos, Margareta Persson, Anders Bjartell

Transl Oncol· October 2022

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Nuclear expression of pSTAT3 and pSTAT3 in the stromal compartment of localized hormone-naïve prostate cancer.
Felicia Elena Marginean, Rebecka Hellsten, Agnieszka Krzyzanowska, Anders Bjartell

Pathol Res Pract· April 2022

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Inhibition of STAT3 augments antitumor efficacy of anti-CTLA-4 treatment against prostate cancer.
Kristina Witt, Susan Evans-Axelsson, Andreas Lundqvist, Martin Johansson, Anders Bjartell, Rebecka Hellsten

Cancer Immunol Immunother· November 2021

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STAT3 inhibition with galiellalactone effectively targets the prostate cancer stem-like cell population.
Giacomo Canesin, Valentina Maggio, Macarena Palominos, Anna Stiehm, Hector R Contreras, Rebecka Hellsten

Sci Rep· August 2020

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The STAT3 inhibitor galiellalactone inhibits the generation of MDSC-like monocytes by prostate cancer cells and decreases immunosuppressive and tumorigenic factors.
Rebecka Hellsten, Lisa Lilljebjörn, Martin Johansson, Karin Leandersson, Anders Bjartell

Prostate· October 2019

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Expression of tSTAT3, pSTAT3 , and pSTAT3 in the epithelial cells of hormone-naïve prostate cancer.
Agnieszka Krzyzanowska, Nicholas Don-Doncow, Felicia Elena Marginean, Alexander Gaber, R William Watson, Rebecka Hellsten

Prostate· May 2019

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Treatment with the WNT5A-mimicking peptide Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model.
Giacomo Canesin, Susan Evans-Axelsson, Rebecka Hellsten, Agnieszka Krzyzanowska, Chandra P Prasad

PLoS One· October 2017

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Expression of STAT3 in Prostate Cancer Metastases.
Nicholas Don-Doncow, Felicia Marginean, Ilsa Coleman, Peter S Nelson, Roy Ehrnström, Rebecka Hellsten

Eur Urol· March 2017

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Preclinical Characterization of 3β-(N-Acetyl l-cysteine methyl ester)-2aβ,3-dihydrogaliellalactone (GPA512), a Prodrug of a Direct STAT3 Inhibitor for the Treatment of Prostate Cancer.
Zilma Escobar, Anders Bjartell, Giacomo Canesin, Susan Evans-Axelsson, Olov Sterner, Rebecka Hellsten

J Med Chem· May 2016

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The STAT3 Inhibitor Galiellalactone Effectively Reduces Tumor Growth and Metastatic Spread in an Orthotopic Xenograft Mouse Model of Prostate Cancer.
Giacomo Canesin, Susan Evans-Axelsson, Rebecka Hellsten, Olov Sterner, Agnieszka Krzyzanowska

Eur Urol· March 2016

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Therapeutic Targeting of Nuclear γ-Tubulin in RB1-Negative Tumors.
Lisa Lindström, Bruno O Villoutreix, Sophie Lehn, Rebecka Hellsten, Elise Nilsson

Mol Cancer Res· July 2015

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Galiellalactone is a direct inhibitor of the transcription factor STAT3 in prostate cancer cells.
Nicholas Don-Doncow, Zilma Escobar, Martin Johansson, Sven Kjellström, Victor Garcia, Rebecka Hellsten

J Biol Chem· June 2014

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The fungal metabolite galiellalactone interferes with the nuclear import of NF-κB and inhibits HIV-1 replication.
Moisés Pérez, Rafael Soler-Torronteras, Juan A Collado, Carmen G Limones, Rebecka Hellsten

Chem Biol Interact· May 2014

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Galiellalactone inhibits stem cell-like ALDH-positive prostate cancer cells.
Rebecka Hellsten, Martin Johansson, Anna Dahlman, Olov Sterner, Anders Bjartell

PLoS One· November 2011

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Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3.
Rebecka Hellsten, Martin Johansson, Anna Dahlman, Nishtman Dizeyi, Olov Sterner

Prostate· February 2008

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A highly conserved protein secreted by the prostate cancer cell line PC-3 is expressed in benign and malignant prostate tissue.
Camilla Valtonen-André, Anders Bjartell, Rebecka Hellsten, Hans Lilja, Pirkko Härkönen

Biol Chem· March 2007

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