Publications by authors named "Reina Mebius"

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Integration of lymphatic vasculature to a human lymph node-on-chip enhances physiological immune properties.
Andrew I Morrison, Jonas Jäger, Charlotte M de Winde, Tanja Konijn, Henk P Roest, Reina E Mebius

Mater Today Bio· December 2025

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Toward immunoprofiling in MDS: A computational study of the bone marrow immune microenvironment.
Margot F van Spronsen, Luca L G Janssen, Tessa Poolman, Theresia M Westers, Yvan Saeys, Reina E Mebius

Cytometry B Clin Cytom· November 2025

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Enhanced MHC Class-II Expression in Fibroblastic Reticular Cells Associates with Maturation.
Janna E G Roet, Catarina Gago da Graça, Michael de Kok, Daphne Panocha, Tanja Konijn, Reina E Mebius

Eur J Immunol· November 2025

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TLR ligand sensing by lymph node FRCs directs intranodal lymphocyte accumulation to promote immune responses.
Antonio P Baptista, Eelco Keuning, Reina E Mebius

iScience· November 2025

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Identification and Mapping of Human Lymph Node Stromal Cell Subsets by Combining Single-Cell RNA Sequencing with Spatial Transcriptomics.
Cristoforo Grasso, Janna E G Roet, Catarina Gago de Graça, Johanna F Semmelink, Michael de Kok, Reina E Mebius

Eur J Immunol· June 2025

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HLA-DR expressing lymph node fibroblasts maintain FoxP3+ regulatory T cells and are reduced in rheumatoid arthritis.
Aoife M O'Byrne, Cristoforo Grasso, Charlotte M de Winde, Aleksandra M Mikula, Catarina Gago da Graça, Reina E Mebius

Clin Exp Immunol· June 2025

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Lymphoma-on-chip model reveals that lymph node stromal cells promote diffuse large B-cell lymphoma survival and migration.
Mohammad Jouybar, Aleksandra M Mikula, Nanouk Zuidmeer, Tanja Konijn, A Vera de Jonge, Reina E Mebius

Mater Today Bio· April 2025

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Functional organotypic human lymph node model with native immune cells benefits from fibroblastic reticular cell enrichment.
Andrew I Morrison, Jesse E Kuipers, Henk P Roest, Luc J W van der Laan, Charlotte M de Winde, Reina E Mebius

Sci Rep· April 2025

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Lymph node fibroblast-produced extracellular matrix shapes immune function.
Daphne Panocha, Janna E G Roet, Jesse E Kuipers, Charlotte M de Winde, Reina E Mebius

Trends Immunol· March 2025

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Integration of Stromal Cells and Hydrogel Below Epithelium Results in Optimal Barrier Properties of Small Intestine Organoid Models.
Melis Asal, Maria Thon, Taco Waaijman, Hetty J Bontkes, Sandra J van Vliet, Reina E Mebius

Biomedicines· December 2024

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Unbiased method for spectral analysis of cells with great diversity of autofluorescence spectra.
Janna E G Roet, Aleksandra M Mikula, Michael de Kok, Cora H Chadick, Juan J Garcia Vallejo, Reina E Mebius

Cytometry A· August 2024

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In-depth immune profiling of peripheral blood mononuclear cells in patients with pancreatic ductal adenocarcinoma reveals discriminative immune subpopulations.
Ernesto Rodriguez, Eline S Zwart, Alsya A Affandi, Jan Verhoeff, Mike de Kok, Reina E Mebius

Cancer Sci· July 2024

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Human lymph node fibroblastic reticular cells maintain heterogeneous characteristics in culture.
Janna E G Roet, Andrew I Morrison, Aleksandra M Mikula, Michael de Kok, Daphne Panocha, Reina E Mebius

iScience· July 2024

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Cancer-on-chip models for metastasis: importance of the tumor microenvironment.
Mohammad Jouybar, Charlotte M de Winde, Katarina Wolf, Peter Friedl, Reina E Mebius

Trends Biotechnol· April 2024

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Towards Full Thickness Small Intestinal Models: Incorporation of Stromal Cells.
Melis Asal, Mila Rep, Hetty J Bontkes, Sandra J van Vliet, Reina E Mebius

Tissue Eng Regen Med· April 2024

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An Organotypic Human Lymph Node Model Reveals the Importance of Fibroblastic Reticular Cells for Dendritic Cell Function.
Andrew I Morrison, Aleksandra M Mikula, Sander W Spiekstra, Michael de Kok, Alsya J Affandi, Reina E Mebius

Tissue Eng Regen Med· April 2024

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Pancreatic cancer-associated fibroblasts modulate macrophage differentiation via sialic acid-Siglec interactions.
Kelly Boelaars, Ernesto Rodriguez, Zowi R Huinen, Chang Liu, Di Wang, Reina E Mebius

Commun Biol· April 2024

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The role of CD56 NK cells in neurodegenerative disorders.
Carla Rodriguez-Mogeda, Chaja M J van Ansenwoude, Lennart van der Molen, Eva M M Strijbis, Reina E Mebius

J Neuroinflammation· February 2024

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Spatial immune composition of tumor microenvironment in patients with pancreatic cancer.
Eline S Zwart, Thomas van Ee, Alsya J Affandi, Lenka N C Boyd, Ernesto Rodriguez, Reina E Mebius

Cancer Immunol Immunother· December 2023

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The immune microenvironment after neoadjuvant therapy compared to upfront surgery in patients with pancreatic cancer.
Eline S Zwart, Thomas van Ee, Deesje Doppenberg, Arantza Farina, Johanna W Wilmink, Reina E Mebius

J Cancer Res Clin Oncol· November 2023

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Unraveling the impact of sialic acids on the immune landscape and immunotherapy efficacy in pancreatic cancer.
Kelly Boelaars, Laura Goossens-Kruijssen, Di Wang, Charlotte M de Winde, Ernesto Rodriguez, Reina E Mebius

J Immunother Cancer· November 2023

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A synthetic human 3D lymphoid model enhancing B-cell survival and functional differentiation.
Maaike V J Braham, Rob S van Binnendijk, Anne-Marie M Buisman, Reina E Mebius, Jelle de Wit

iScience· January 2023

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Factors that influence the pancreatic and duodenal microbiome in patients undergoing pancreatic surgery.
Eline S Zwart, Suzanne Jeleniewski, Lenka N C Boyd, Laura L Meijer, Jisce R Puik, Reina E Mebius

PLoS One· December 2022

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Fcα Receptor-1-Activated Monocytes Promote B Lymphocyte Migration and IgA Isotype Switching.
Amélie V Bos, Melissa M J van Gool, Annelot C Breedveld, Richard van der Mast, Casper Marsman, Reina E Mebius

Int J Mol Sci· September 2022

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The role of retinoic acid in the production of immunoglobulin A.
Amelie Bos, Marjolein van Egmond, Reina Mebius

Mucosal Immunol· April 2022

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